Human Apolipoprotein B/ApoB Biotinylated Antibody Summary
Met1206-Asp1413
Accession # NP_000375
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Apolipoprotein B/ApoB
ApoB is a component of LDL and VLDL particles and chylomicans. ApoB100, the full-length ApoB synthesized in the liver, is a 512 kDa secreted palmetoylated glycoprotein that contains 4536 amino acid residues. A truncated ApoB designated ApoB48, containing the N-terminal 48% of ApoB100, is also produced by the intestine as a result of post-transcriptional modification of the ApoB mRNA. Additionally, C-terminal truncated ApoB, varying in length from ApoB25 to ApoB89, exists as a result of mutations in the ApoB gene. Within the region used as the immunogen, the amino acid sequence of the human peptide is 80% and 82% identical to the mouse and canine sequence, respectively.
Product Datasheets
Citations for Human Apolipoprotein B/ApoB Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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Elevated apolipoprotein C3 augments diabetic kidney disease and associated atherosclerosis in type 2 diabetes
Authors: Cervantes, J;Koska, J;Kramer, F;Akilesh, S;Alpers, CE;Mullick, AE;Reaven, P;Kanter, JE;
JCI insight
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes
Authors: JE Kanter, B Shao, F Kramer, S Barnhart, M Shimizu-Al, T Vaisar, MJ Graham, RM Crooke, CR Manuel, RA Haeusler, D Mar, K Bomsztyk, JE Hokanson, GL Kinney, JK Snell-Berg, JW Heinecke, KE Bornfeldt
J. Clin. Invest., 2019-07-11;130(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis
Authors: S Kijani, AM Vázquez, M Levin, J Borén, P Fogelstran
Physiol Rep, 2017-07-01;5(14):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes
Authors: Jenny E. Kanter, Karin E. Bornfeldt
Journal of Lipid Research
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