Human BAI3 (NP_001695) VersaClone cDNA

Catalog #: RDC0755 Datasheet / COA / SDS

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RDC0755

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Human BAI3 (NP_001695) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: BAI3

BAI3 (Brain angiogenesis inhibitor 3) is an adhesion GPCR that plays a role in neuronal synapse formation and maintenance. It is primarily expressed post-synaptically in the cerebral cortex and on cerebellar Purkinje cells, and it binds to the TNF-like proteins C1qL1, 2, 3, and 4. BAI3 interaction with C1qL1 is required for the formation and maintenance of excitatory synapses between climbing fibers and parallel fibers with Purkinje cells. BAI3 ligation can also reduce excitatory synaptic density in hippocampal neurons, decrease dendrite arborization, and promote axon pruning in climbing fibers. It is additionally expressed in developing muscle where it is required for myoblast fusion.

Long Name

Brain-specific Angiogenesis Inhibitor 3

Entrez Gene IDs

577 (Human); 210933 (Mouse); 301309 (Rat)

Alternate Names

BAI3; brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain-specific angiogenesis inhibitor 3); KIAA0550MGC133100