Human beta-Defensin 2 Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF2758
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Human beta-Defensin 2 Biotinylated Antibody Summary

Species Reactivity
Human
Specificity
Detects human beta ‑Defensin 4/2 in Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human beta ‑Defensin 4/2
Gly24-Pro64
Accession # O15263
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human beta -Defensin 4/2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: beta-Defensin 2

Human BD-2, also known as defensin beta 2 (DEFB-2), is a secreted, 41 amino acid residue anti-microbial protein belonging to the defensin family. Mature defensins are cationic proteins with three intramolecular disulfides and a characteristic triple-stranded beta -sheet. Human BD-2 expression is induced by inflammatory signals in multiple tissues, including airway epithelial cells and keratinocytes. At the amino acid sequence level, human BD-2 shares 98% and 51% homology with the proteins from rhesus monkey and rat, respectively.

Long Name
Defensin 2 beta
Entrez Gene IDs
1673 (Human)
Alternate Names
BD-2; betaDefensin 2; beta-Defensin 2; DEFB2; DEFB-2; DEFB2DEFB102; DEFB4A; DEFB4B; DEFB4beta-defensin 4A; Defensin, beta 2Skin-antimicrobial peptide 1; defensin, beta 4; defensin, beta 4A; HBD-2; SAP-1; SAP1BD-2

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