Human BMP-2/BMP-4 Antibody

Name: Human BMP-2/BMP-4 Antibody
Brand: R&D Systems
SKU: MAB355
Rating: 5 (2 reviews)

Catalog #: MAB355
2 Citations 2 Reviews Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB355-SP
MAB355-100
MAB355-500

All BMP-2/BMP-4 Antibodies

Product Details

Citations (2)

FAQs

Supplemental Products

Reviews (2)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human BMP-2/BMP-4 Antibody Summary

Species Reactivity

Human

Specificity

Detects human BMP-2 and human BMP-4 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows no cross‑reactivity with recombinant human (rh) BMP-5 or rhBMP-6.

Source

Monoclonal Mouse IgG_2B Clone # 65529

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant human BMP-2
Ala284-Arg396
Accession # P12643

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human BMP‑2 (Catalog # 355-BM)
Recombinant Human BMP‑4 (Catalog # 314-BP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: BMP-2/BMP-4

BMP-2 and BMP-4 belong to a family of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily, BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs.

Long Name

Bone Morphogenetic Protein 2/4

Entrez Gene IDs

650 (Human); 12156 (Mouse); 29373 (Rat)

Alternate Names

BDA2; BMP-2; BMP-2/BMP-4; BMP2A; BMP-2A; BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human BMP-2/BMP-4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach.
Authors: Bleuming SA, Kodach LL, Garcia Leon MJ, Richel DJ, Peppelenbosch MP, Reitsma PH, Hardwick JC, van den Brink GR
J. Pathol., 2006-06-01;209(2):190-7.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P
Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.
Authors: van den Brink GR, Hardwick JC, Tytgat GN, Brink MA, Ten Kate FJ, Van Deventer SJ, Peppelenbosch MP
Gastroenterology, 2001-08-01;121(2):317-28.
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: IHC-P