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Human BMP-7 Biotinylated Antibody

Catalog #: BAM354
1 Citation Datasheet / COA / SDS
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BAM354
Product Details
Citations (1)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human BMP-7 Biotinylated Antibody Summary

Species Reactivity
Human
Specificity
Detects human BMP-7 in ELISAs. In ELISAs, this antibody shows less than 0.125% cross-reactivity with recombinant human (rh) BMP‑2, rhBMP‑3, rhBMP‑4, rhBMP‑5, rhBMP‑6, rhBMP‑8, rhTGF‑ beta 1, rhTGF‑ beta 2, or rhTGF‑ beta 3.
Source
Monoclonal Mouse IgG1 Clone # 164324
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human BMP‑7
Arg292-His431
Accession # P18075
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample

Human BMP-7 Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Detection (Matched Antibody Pair)
0.5-2.0 µg/mL 

Use in combination with:

Capture Reagent: Human BMP‑7 Antibody (Catalog # MAB3542)

Standard: Recombinant Human BMP-7 Protein (Catalog # 354-BP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: BMP-7

BMP-7, also known as Osteogenic Protein 1 (OP-1), is one of at least 15 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs regulate cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs, and growth, differentiation, chemotaxis, and apoptosis of various cell types. Biologically active BMP-7 is a disulfide-linked homodimer. Cellular responses to BMP-7 have been shown to be mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.

Long Name
Bone Morphogenetic Protein 7
Entrez Gene IDs
655 (Human); 12162 (Mouse); 85272 (Rat)
Alternate Names
BMP7; BMP-7; bone morphogenetic protein 7; Eptotermin alfa; OP-1; OP-1OP1; Osteogenic protein 1

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Citation for Human BMP-7 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds
    Authors: R Oude Egber, HM Zegelaar, N El Boujnou, EMM Versteeg, WF Daamen, R Brock
    Pharmaceutics, 2022-08-02;14(8):.
    Species: Mouse
    Sample Types: Complex Sample Type
    Applications: ELISA Detection

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