Human CCR10 (NP_057686) VersaClone cDNA

Catalog #: RDC0022 Datasheet / COA / SDS

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RDC0022

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Human CCR10 (NP_057686) VersaClone cDNA Summary

Specifications

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: CCR10

CCR10 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR10 is 362 amino acids (aa) in length with a predicted molecular weight of 38 kDa. Mouse and rat CCR10 share 88% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration.

Entrez Gene IDs

2826 (Human); 12777 (Mouse); 363682 (Rat)

Alternate Names

CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2

Related Research Areas

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