Human CD14 Quantikine ELISA Kit Summary
Sample Values
Serum/Plasma - Samples from apparently healthy volunteers were evaluated for the presence of human CD14 in this assay. No medical histories were available for the donors used in this study.Sample Type | Mean (ng/mL) | Range (ng/mL) |
Serum (n=66) | 1900 | 800-3200 |
EDTA plasma (n=34) | 1800 | 1200-2600 |
Heparin plasma (n=34) | 1900 | 1200-3100 |
Citrate plasma (n=34) | 2000 | 1500-3000 |
Cell Culture Supernates - - Human peripheral blood mononuclear cells (5 x 106 cells/mL) were cultured in RPMI supplemented with 5% fetal bovine serum, 50 μM beta -mercaptoethanol, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cells were cultured unstimulated or stimulated with 10 μg/mL PHA. Aliquots of the cell culture supernates were removed on days 1, 3, and 5 and assayed for levels of human CD14.
Sample Type | Day 1 (pg/mL) | Day 3 (pg/mL) | Day 5 (pg/mL) |
Unstimulated | 5070 | 9457 | 7762 |
Stimulated | 12,287 | 22,343 | 24,720 |
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean (pg/mL) | 1111 | 2158 | 4187 | 1159 | 2298 | 4346 |
Standard Deviation | 71 | 104 | 216 | 86 | 153 | 209 |
CV% | 6.4 | 4.8 | 5.2 | 7.4 | 6.7 | 4.8 |
Recovery
The recovery of sCD14 spiked to three different levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=5) | 91 | 85-105 |
Citrate Plasma (n=5) | 102 | 88-110 |
EDTA Plasma (n=5) | 98 | 90-107 |
Heparin Plasma (n=5) | 96 | 91-104 |
Serum (n=5) | 98 | 84-107 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: CD14
CD14 is a glycoprotein that mediates the interaction of lipopolysaccharide (LPS, endotoxin)with cells, thereby signaling the presence of gram-negative bacteria (1-3). CD14 is eithersoluble (CD14) (4, 5) or membrane-bound (mCD14) by a glycosylphosphatidylinositol (GPI)anchor (6, 7). mCD14 is a 55 kDa glycoprotein (1), while CD14 varies from about 43 to 53 kDa,depending on the degree of glycosylation and whether it was synthesized without the anchoror was shed by phospholipase cleavage of the anchor or by proteolysis (12-14). There is noevidence for different mRNAs for m- and CD14. There is no apparent sequence homology withother proteins. The sequence of human CD14 is 63-73% identical to that of mouse, rat, or rabbitCD14 (15).
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 100 µL of Assay Diluent to each well.
- Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 3 hours.
- Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
- Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
- Aspirate and wash 4 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Human CD14 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
140
Citations: Showing 1 - 10
Filter your results:
Filter by:
-
Elevated intestinal fatty acid-binding protein levels as a marker of portal hypertension and gastroesophageal varices in cirrhosis
Authors: Miuma, S;Miyaaki, H;Taura, N;Kanda, Y;Matsuo, S;Tajima, K;Takahashi, K;Nakao, Y;Fukushima, M;Haraguchi, M;Sasaki, R;Ozawa, E;Ichikawa, T;Nakao, K;
Scientific reports
Species: Human
Sample Types: Serum
-
Inflammatory Biomarker Reduction With Fostemsavir Over 96 Weeks in Heavily Treatment-Experienced Adults With Multidrug-Resistant HIV-1 in the BRIGHTE Study
Authors: Clark, A;Prakash, M;Chabria, S;Pierce, A;Castillo-Mancilla, JR;Wang, M;Du, F;Tenorio, AR;
Open forum infectious diseases
Species: Human
Sample Types: Serum, Plasma
-
Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants
Authors: Evans, C;Mutasa, K;Rukobo, S;Govha, M;Mushayanembwa, P;Chasekwa, B;Majo, FD;Tavengwa, NV;Broad, J;Noble, C;Gough, EK;Kelly, P;Bourke, CD;Humphrey, JH;Ntozini, R;Prendergast, AJ;
Nature communications
Species: Human
Sample Types: Plasma
-
HIV-associated gut microbial alterations are dependent on host and geographic context
Authors: Rocafort, M;Gootenberg, DB;Luévano, JM;Paer, JM;Hayward, MR;Bramante, JT;Ghebremichael, MS;Xu, J;Rogers, ZH;Munoz, AR;Okello, S;Kim, JH;Sentongo, R;Wagubi, R;Lankowski, A;Maruapula, S;Zhao, G;Handley, SA;Mosepele, M;Siedner, MJ;Kwon, DS;
Nature communications
Species: Human
Sample Types: Plasma
-
Disrupted balance between pro-inflammatory lipid mediators and anti-inflammatory specialized pro-resolving mediators is linked to hyperinflammation in patients with alcoholic hepatitis
Authors: Li, W;Xia, Y;Yang, J;Sanyal, AJ;Shah, VH;Chalasani, NP;Yu, Q;
medRxiv : the preprint server for health sciences
Species: Human
Sample Types: Plasma
-
Design and Fabrication of a 3D-Printed Microfluidic Immunoarray for Ultrasensitive Multiplexed Protein Detection
Authors: Hiniduma, K;Bhalerao, KS;De Silva, PIT;Chen, T;Rusling, JF;
Micromachines
Species: Human
Sample Types: Protein, Serum
-
HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria
Authors: Planchais, C;Molinos-Albert, LM;Rosenbaum, P;Hieu, T;Kanyavuz, A;Clermont, D;Prazuck, T;Lefrou, L;Dimitrov, JD;Hüe, S;Hocqueloux, L;Mouquet, H;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
-
Proton pump inhibitor treatment aggravates bacterial translocation in patients with advanced cirrhosis and portal hypertension
Authors: Sturm, L;Hirose, M;Stolz, L;Schultheiss, M;Zoldan, K;Reincke, M;Huber, JP;Kaeser, R;Boettler, T;Thimme, R;Albert, E;Busch, H;Künstner, A;Bettinger, D;
mBio
Species: Human
Sample Types: Plasma
-
Milk-Fat-Globule-Membrane-Enriched Dairy Milk Compared with a Soy-Lecithin-Enriched Beverage Did Not Adversely Affect Endotoxemia or Biomarkers of Gut Barrier Function and Cardiometabolic Risk in Adults with Metabolic Syndrome: A Randomized Controlled Crossover Trial
Authors: Pokala, A;Quarles, WR;Ortega-Anaya, J;Jimenez-Flores, R;Cao, S;Zeng, M;Hodges, JK;Bruno, RS;
Nutrients
Species: Human
Sample Types: Serum
-
Psychological stress is associated with arterial inflammation in people living with treated HIV infection
Authors: Chow, FC;Mundada, NS;Abohashem, S;La Joie, R;Iaccarino, L;Arechiga, VM;Swaminathan, S;Rabinovici, GD;Epel, ES;Tawakol, A;Hsue, PY;
Brain, behavior, and immunity
Species: Human
Sample Types: Plasma
-
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia
Authors: Mabrey, FL;Nian, H;Yu, C;Barnes, EM;Malhotra, U;Mikacenic, C;Goldstein, J;O'Mahony, DS;Garcia-Diaz, J;Finn, P;Voelker, K;Morrell, ED;Self, WH;Becker, PM;Martin, TR;Wurfel, MM;
EBioMedicine
Species: Human
Sample Types: Serum
-
Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys
Authors: Q Le Hingrat, P Sette, C Xu, AR Rahmberg, L Tarnus, H Annapuredd, A Kleinman, E Brocca-Cof, R Sivanandha, S Sivanandha, T He, DJ Capreri, D Ma, JD Estes, JM Brenchley, C Apetrei, I Pandrea
Nature Communications, 2023-02-22;14(1):979.
Species: Primate - Chlorocebus sabaeus (Green Monkey)
Sample Types: Plasma
-
Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus
Authors: LP Kincer, SB Joseph, MM Gilleece, BM Hauser, S Sizemore, S Zhou, C Di Germani, H Zetterberg, D Fuchs, SG Deeks, S Spudich, M Gisslen, RW Price, R Swanstrom
Nature Microbiology, 2023-01-30;8(2):260-271.
Species: Human
Sample Types: CSF
-
Cerebrovascular pulsatility index is higher in chronic kidney disease
Authors: ES Oh, KA Freeberg, CN Steele, W Wang, H Farmer-Bai, ME Coppock, DR Seals, M Chonchol, MJ Rossman, DH Craighead, KL Nowak
Physiological Reports, 2023-01-01;11(1):e15561.
Species: Human
Sample Types: Serum
-
Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis
Authors: RO Ali, GM Quinn, R Umarova, JA Haddad, GY Zhang, EC Townsend, L Scheuing, KL Hill, M Gewirtz, S Rampertaap, SD Rosenzweig, AT Remaley, JM Han, V Periwal, H Cai, PJ Walter, C Koh, EB Levy, DE Kleiner, O Etzion, T Heller
Nature Microbiology, 2022-12-15;0(0):.
Species: Human
Sample Types: Serum
-
Long-Term Associations between Human Cytomegalovirus Antibody Levels with All-Cause Mortality and Cardiovascular Outcomes in an Australian Community-Based Cohort
Authors: S Lee, N van den Be, A Castley, M Divitini, M Knuiman, P Price, D Nolan, F Sanfilippo, G Dwivedi
Viruses, 2022-11-29;14(12):.
Species: Human
Sample Types: Serum
-
The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis
Authors: J Parantaine, G Barreto, R Koivuniemi, H Kautiainen, D Nordström, E Moilanen, M Hämäläinen, M Leirisalo-, K Nurmi, KK Eklund
Arthritis Research & Therapy, 2022-11-21;24(1):256.
Species: Human
Sample Types: Serum
-
Longitudinal Assessment of Multiple Immunological and Inflammatory Parameters during Successful DAA Therapy in HCV Monoinfected and HIV/HCV Coinfected Subjects
Authors: P Zuccalà, T Latronico, R Marocco, S Savinelli, S Vita, F Mengoni, T Tieghi, C Borgo, B Kertusha, A Carraro, G D'Ettorre, V Vullo, CM Mastroiann, GM Liuzzi, M Lichtner
International Journal of Molecular Sciences, 2022-10-08;23(19):.
Species: Human
Sample Types: Plasma
-
Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV
Authors: TE Peterson, C Landon, SA Haberlen, F Bhondoekha, MW Plankey, FJ Palella, DA Piggott, JB Margolick, TT Brown, WS Post, KC Wu
BMC cardiovascular disorders, 2022-09-03;22(1):393.
Species: Human
Sample Types: Serum
-
The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
Authors: Z Strongin, TN Hoang, GK Tharp, AR Rahmberg, JL Harper, K Nguyen, L Franchitti, B Cervasi, M Lee, Z Zhang, EA Boritz, G Silvestri, VC Marconi, SE Bosinger, JM Brenchley, DA Kulpa, M Paiardini
PloS Pathogens, 2022-07-22;18(7):e1010723.
Species: Human
Sample Types: Plasma
-
Vascular Calcification and the Gut and Blood Microbiome in Chronic Kidney Disease Patients on Peritoneal Dialysis: A Pilot Study
Authors: A Merino-Rib, R Araujo, L Pereira, J Campos, L Barreiros, MA Segundo, N Silva, CFFA Costa, J Quelhas-Sa, F Trindade, I Falcão-Pir, I Alencastre, IB Dumitrescu, B Sampaio-Ma
Biomolecules, 2022-06-21;12(7):.
Species: Human
Sample Types: Plasma
-
Impact of illicit opioid use on markers of monocyte activation and systemic inflammation in people living with HIV
Authors: A Kholodnaia, K So-Armah, D Cheng, N Gnatienko, G Patts, JH Samet, M Freiberg, D Lioznov
PLoS ONE, 2022-05-05;17(5):e0265504.
Species: Human
Sample Types: Serum
-
Inflammatory Markers after Switching to a Dual Drug Regimen in HIV-Infected Subjects: A Two-Year Follow-Up
Authors: M Vassallo, J Durant, R Fabre, L Lotte, A Sindt, A Puchois, A De Monte, R Cezar, P Corbeau, C Pradier
Viruses, 2022-04-28;14(5):.
Species: Human
Sample Types: Plasma
-
Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study
Authors: C Amadieu, L Maccioni, S Leclercq, AM Neyrinck, NM Delzenne, P de Timary, P Stärkel
EBioMedicine, 2022-04-28;80(0):104033.
Species: Human
Sample Types: Plasma
-
Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring
Authors: J Štšepetova, K Simre, A Tagoma, O Uibo, A Peet, H Siljander, V Tillmann, M Knip, R Mändar, R Uibo
Scientific Reports, 2022-04-22;12(1):6607.
Species: Human
Sample Types: Breast Milk
-
Immune Activation in Primary Human Immunodeficiency Virus: Influence of Duration of Infection, Treatment, and Substance Use
Authors: T Gilada, SR Schnittman, E White, J Mercader, Y Wang, S Dasgupta, R Valdez, D Pinto-Sant, S Pasalar, J Sanchez, P Gonzales, JR Lama, R Bender Ign, A Duerr
Open forum infectious diseases, 2022-03-24;9(6):ofac155.
Species: Human
Sample Types: Plasma
-
Blood-brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins
Authors: L Hernandez, LJ Ward, S Arefin, T Ebert, A Laucyte-Ci, GOING-FWD, O Heimbürger, P Barany, L Wennberg, P Stenvinkel, K Kublickien
Scientific Reports, 2022-03-15;12(1):4414.
Species: Human
Sample Types: Serum
-
Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial
Authors: T Sainz, L Diaz, D Rojo, MI Clemente, C Barbas, MJ Gosalbes, N Jimenez-He, L Escosa, S Guillen, JT Ramos, MÁ Muñoz-Fern, ML Navarro, MJ Mellado, S Serrano-Vi
Nutrients, 2022-02-26;14(5):.
Species: Human
Sample Types: Plasma
-
Maternal inflammatory and omega-3 fatty acid pathways mediate the association between socioeconomic disadvantage and childhood cognition
Authors: W Marx, S Thomson, M O'Hely, C Symeonides, F Collier, MLK Tang, A Loughman, D Burgner, R Saffery, C Pham, T Mansell, PD Sly, P Vuillermin, S Ranganatha, AL Ponsonby, Barwon Inf
Brain, Behavior, and Immunity, 2021-12-08;100(0):211-218.
Species: Human
Sample Types: Serum
-
Translocating lipopolysaccharide correlates with the severity of enterovirus A71-induced HFMD by promoting pro-inflammation and viral IRES activity
Authors: Y Wang, K Dan, X Xue, X Yang, X Feng, Q Yang, J Yang, B Chen
Gut pathogens, 2021-11-22;13(1):69.
Species: Human
Sample Types: Serum
-
Biomarkers of disease severity in patients with visceral leishmaniasis co-infected with HIV
Authors: GR Ferreira, JR Santos-Oli, ML Silva-Frei, M Honda, DL Costa, AM Da-Cruz, CHN Costa
Cytokine, 2021-10-27;149(0):155747.
Species: Human
Sample Types: Serum
-
Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response
Authors: N Zhang, Y Gou, S Liang, N Chen, Y Liu, Q He, J Zhang
Journal of Immunology Research, 2021-10-20;2021(0):4973589.
Species: Human
Sample Types: Plasma
-
A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis
Authors: LC Alexander, G McHorse, JL Huebner, AC Bay-Jensen, MA Karsdal, VB Kraus
Arthritis Research & Therapy, 2021-08-31;23(1):226.
Species: Human
Sample Types: Plasma
-
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms
Authors: MJ Peluso, AN Deitchman, L Torres, NS Iyer, SE Munter, CC Nixon, J Donatelli, C Thanh, S Takahashi, J Hakim, K Turcios, O Janson, R Hoh, V Tai, Y Hernandez, EA Fehrman, MA Spinelli, M Gandhi, L Trinh, T Wrin, CJ Petropoulo, FT Aweeka, I Rodriguez-, JD Kelly, JN Martin, SG Deeks, B Greenhouse, RL Rutishause, TJ Henrich
Cell Reports, 2021-08-06;36(6):109518.
Species: Human
Sample Types: Serum
-
Soluble cluster of differentiation 14 levels elevated in bile from gallbladder cancer cases from Shanghai, China
Authors: VL Brun, AF Corbel, AW Hsing, TJ Kemp, AL Van Dyke, A Hildesheim, B Zhu, YT Gao, LA Pinto, J Koshiol
Scientific Reports, 2021-06-28;11(1):13405.
Species: Human
Sample Types: Bile
-
Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques
Authors: MP Wood, CI Jones, A Lippy, BG Oliver, B Walund, KA Fancher, BS Fisher, PJ Wright, JT Fuller, P Murapa, J Habib, M Mavigner, A Chahroudi, DN Sather, DH Fuller, DL Sodora
PloS Pathogens, 2021-05-07;17(5):e1009575.
Species: Human
Sample Types: Plasma
-
Inflammatory Markers During Early Treatment of Seroconverters in a Randomized Placebo-Controlled Trial of PrEP (ANRS-IPERGAY)
Authors: S Chawki, I Charreau, A Gabassi, D Carette, E Cua, L Cotte, G Pialoux, C Pintado, L Meyer, ML Chaix, C Delaugerre, JM Molina
Open forum infectious diseases, 2021-03-20;8(3):ofab085.
Species: Human
Sample Types: Plasma
-
B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy
Authors: S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl
PLoS ONE, 2021-03-19;16(3):e0248056.
Species: Human
Sample Types: Plasma
-
Insomnia symptoms and biomarkers of monocyte activation, systemic inflammation, and coagulation in HIV: Veterans Aging Cohort Study
Authors: BM Polanka, S Kundu, KA So-Armah, MS Freiberg, SK Gupta, TCB Zapolski, AT Hirsh, RJ Bedimo, MJ Budoff, AA Butt, CH Chang, SS Gottlieb, VC Marconi, JA Womack, JC Stewart
PLoS ONE, 2021-02-09;16(2):e0246073.
Species: Human
Sample Types: Serum
-
Identifying a biological signature of prenatal maternal stress
Authors: JM Keane, AS Khashan, FP McCarthy, LC Kenny, JM Collins, SM O'Donovan, JR Brown, JF Cryan, TG Dinan, G Clarke, SM O'Mahony
JCI Insight, 2021-01-25;0(0):.
Species: Human
Sample Types: Serum
-
Identification of distinct immune activation profiles in adult humans
Authors: R Cezar, A Winter, D Desigaud, M Pastore, L Kundura, AM Dupuy, C Cognot, T Vincent, C Reynes, C Dunyach-Re, JP Lavigne, R Sabatier, P Le Merre, E Maggia, P Corbeau
Scientific Reports, 2020-11-30;10(1):20824.
Species: Human
Sample Types: Plasma
-
The Differences between Gluten Sensitivity, Intestinal Biomarkers and Immune Biomarkers in Patients with First-Episode and Chronic Schizophrenia
Authors: M Dzikowski, D Juchnowicz, I Dzikowska, J Rog, M Próchnicki, M Kozio?, H Karakula-J
J Clin Med, 2020-11-18;9(11):.
Species: Human
Sample Types: Serum
-
Endotoxemia coupled with heightened inflammation predicts future depressive symptoms
Authors: AA Madison, R Andridge, AC Padin, S Wilson, MT Bailey, CM Alfano, SP Povoski, AM Lipari, DM Agnese, WE Carson, WB Malarkey, JK Kiecolt-Gl
Psychoneuroendocrinology, 2020-10-08;122(0):104864.
Species: Human
Sample Types: Serum
-
Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
Authors: DR Beers, W Zhao, DW Neal, JR Thonhoff, AD Thome, A Faridar, S Wen, J Wang, SH Appel
Scientific Reports, 2020-09-17;10(1):15295.
Species: Human
Sample Types: Serum
-
Interferon-alpha alters host glycosylation machinery during treated HIV infection
Authors: LB Giron, F Colomb, E Papasavvas, L Azzoni, X Yin, M Fair, A Anzurez, M Damra, K Mounzer, JR Kostman, P Tebas, U O'Doherty, H Tateno, Q Liu, MR Betts, LJ Montaner, M Abdel-Mohs
EBioMedicine, 2020-08-19;59(0):102945.
Species: Human
Sample Types: Plasma
-
Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
Authors: SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, J Carrión-Pe, R Girard, J Koskimäki, D Zhang, A Stadnik, SG Romanos, SB Lyne, R Shenkar, K Yan, C Lee, A Akers, L Morrison, M Robinson, A Zafar, K Bittinger, H Kim, JA Gilbert, ML Kahn, L Shen, IA Awad
Nat Commun, 2020-05-27;11(1):2659.
Species: Human
Sample Types: Plasma
-
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Authors: S Vieira-Sil, G Falony, E Belda, T Nielsen, J Aron-Wisne, R Chakaroun, SK Forslund, K Assmann, M Valles-Col, TTD Nguyen, S Proost, E Prifti, V Tremaroli, N Pons, E Le Chateli, F Andreelli, JP Bastard, LP Coelho, N Galleron, TH Hansen, JS Hulot, C Lewinter, HK Pedersen, B Quinquis, C Rouault, H Roume, JE Salem, NB Søndertoft, S Touch, ME Dumas, SD Ehrlich, P Galan, JP Gøtze, T Hansen, JJ Holst, L Køber, I Letunic, J Nielsen, JM Oppert, M Stumvoll, H Vestergaar, JD Zucker, P Bork, O Pedersen, F Bäckhed, K Clément, J Raes
Nature, 2020-05-06;581(7808):310-315.
Species: Human
Sample Types: Serum
-
Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals
Authors: M Nayrac, M Requena, C Loiseau, M Cazabat, B Suc, N Carrere, K Barange, L Alric, G Martin-Blo, J Izopet, P Delobel
Mucosal Immunol, 2020-04-28;0(0):.
Species: Human
Sample Types: Plasma
-
Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo
Authors: CL Vinton, CE Starke, AM Ortiz, SH Lai, JK Flynn, O Sortino, K Knox, I Sereti, JM Brenchley
Pathog Immun, 2020-04-24;5(1):68-88.
Species: Human, Rhesus Macaca (Macaque)
Sample Types: Plasma
-
Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection
Authors: LB Giron, CE Tanes, MH Schleimann, PA Engen, LM Mattei, A Anzurez, M Damra, H Zhang, K Bittinger, F Bushman, A Kossenkov, PW Denton, H Tateno, A Keshavarzi, AL Landay, M Abdel-Mohs
Mucosal Immunol, 2020-03-09;0(0):.
Species: Human
Sample Types: Plasma
-
African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity
Authors: KD Raehtz, F Barrenäs, C Xu, K Busman-Sah, A Valentine, L Law, D Ma, BB Policicchi, V Wijewardan, E Brocca-Cof, A Trichel, M Gale, BF Keele, JD Estes, C Apetrei, I Pandrea
PLoS Pathog., 2020-03-02;16(3):e1008333.
Species: Primate
Sample Types: Plasma
-
New signatures of poor CD4 cell recovery after suppressive antiretroviral therapy in HIV-1-infected individuals: involvement of miR-192, IL-6, sCD14 and miR-144
Authors: F Hernández-, MJ Ruiz-de-Le, I Rosado-Sán, E Vázquez, M Leal, S Moreno, F Vidal, J Blanco, YM Pacheco, A Vallejo
Sci Rep, 2020-02-19;10(1):2937.
Species: Human
Sample Types: Plasma
-
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
Authors: Y Wang, L Lifshitz, K Gellatly, CL Vinton, K Busman-Sah, S McCauley, P Vangala, K Kim, A Derr, S Jaiswal, A Kucukural, P McDonel, PW Hunt, T Greenough, J Houghton, M Somsouk, JD Estes, JM Brenchley, M Garber, SG Deeks, J Luban
Nat. Immunol., 2020-02-17;21(3):274-286.
-
Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection
Authors: JB Gorin, DFG Malone, B Strunz, T Carlsson, S Aleman, NK Björkström, K Falconer, JK Sandberg
Sci Rep, 2020-02-07;10(1):2081.
Species: Human
Sample Types: Plasma
-
Factor Xa Inhibition Reduces Coagulation Activity but Not Inflammation Among People With HIV: A Randomized Clinical Trial
Authors: JV Baker, J Wolfson, T Peterson, M Mooberry, M Gissel, H Mystakelis, MW Henderson, K Garcia-Mye, FS Rhame, TW Schacker, KE Brummel-Zi, I Sereti, NS Key, RP Tracy
Open Forum Infect Dis, 2020-02-01;7(2):ofaa026.
Species: Human
Sample Types: Serum
-
Impact of Raltegravir or Efavirenz on Cell-Associated Human Immunodeficiency Virus-1 (HIV-1) Deoxyribonucleic Acid and Systemic Inflammation in HIV-1/Tuberculosis Coinfected Adults Initiating Antiretroviral Therapy
Authors: HM Delagrever, C Bauduin, N De Castro, B Grinsztejn, M Chevrier, F Jouenne, S Mourah, I Kalidi, JH Pilotto, C Brites, N Tregnago B, A Amara, L Wittkop, JM Molina, C Delaugerre
Open Forum Infect Dis, 2020-01-11;7(2):ofz549.
Species: Human
Sample Types: Whole Blood
-
Antibiotic-induced microbiome perturbations are associated with significant alterations to colonic mucosal immunity in rhesus macaques
Authors: JA Manuzak, AS Zevin, R Cheu, B Richardson, J Modesitt, T Hensley-Mc, C Miller, AT Gustin, E Coronado, T Gott, M Fang, M Cartwright, S Wangari, B Agricola, D May, E Smith, HB Hampel, M Gale, CM Cameron, MJ Cameron, J Smedley, NR Klatt
Mucosal Immunol, 2019-12-04;0(0):.
Species: Human
Sample Types: Plasma
-
Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study
Authors: JR Chu, SY Kang, SE Kim, SJ Lee, YC Lee, MK Sung
World J. Gastroenterol., 2019-10-28;25(40):6129-6144.
Species: Human
Sample Types: Serum
-
Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests
Authors: N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch
BMC Immunol., 2019-09-14;20(1):33.
Species: Human
Sample Types: Serum
-
Predictors of Obesity among Gut Microbiota Biomarkers in African American Men with and without Diabetes
Authors: E Barengolts, SJ Green, GE Chlipala, BT Layden, Y Eisenberg, M Priyadarsh, LR Dugas
Microorganisms, 2019-09-05;7(9):.
Species: Human
Sample Types: Serum
-
Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis
Authors: DT Claiborne, EP Scully, CD Palmer, JL Prince, GN Macharia, J Kopycinski, CM Michelo, HW Wiener, R Parker, K Nganou-Mak, D Douek, M Altfeld, J Gilmour, MA Price, J Tang, W Kilembe, SA Allen, E Hunter
PLoS Pathog., 2019-08-26;15(8):e1007981.
Species: Human
Sample Types: Plasma
-
Pretransplant Levels of C-Reactive Protein,�Soluble TNF Receptor-1, and�CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients
Authors: JF Camargo, S Pallikkuth, I Moroz, Y Natori, ML Alcaide, A Rodriguez, G Guerra, GW Burke, S Pahwa
Kidney Int Rep, 2019-08-19;4(12):1705-1716.
Species: Human
Sample Types: Plamsa
-
Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1
Authors: C Missailidi, N Sørensen, S Ashenafi, W Amogne, E Kassa, A Bekele, M Getachew, N Gebreselas, A Aseffa, G Aderaye, J Andersson, S Brighenti, P Bergman
Nutrients, 2019-07-21;11(7):.
Species: Human
Sample Types: Plasma
-
Bacterial Translocation and Host Immune Activation in Chronic Hepatitis C Infection
Authors: MS Moon, G Quinn, EC Townsend, RO Ali, GY Zhang, A Bradshaw, K Hill, H Guan, D Hamilton, DE Kleiner, C Koh, T Heller
Open Forum Infect Dis, 2019-07-01;6(7):.
Species: Human
Sample Types: Serum
-
Evolving understanding of cardiovascular, cerebrovascular and peripheral arterial disease in people living with HIV and role of novel biomarkers. A study of the Spanish CoRIS cohort, 2004-2015
Authors: M Masiá, S Padilla, JA García, J García-Abe, M Fernández, I Bernardino, M Montero, J Peraire, B Pernas, F Gutiérrez
PLoS ONE, 2019-04-26;14(4):e0215507.
Species: Human
Sample Types: Plasma
-
TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients
Authors: A Joshi, EB Punke, T Mehmetoglu, DP Peralta, H Garg
BMC Infect. Dis., 2019-01-16;19(1):56.
Species: Human
Sample Types: Plasma
-
Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals
Authors: SC Lee, LL Chua, SH Yap, TF Khang, CY Leng, RI Raja Azwa, SR Lewin, A Kamarulzam, YL Woo, YAL Lim, P Loke, R Rajasuriar
Sci Rep, 2018-09-24;8(1):14277.
Species: Human
Sample Types: Plasma
-
HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers
Authors: R Sharaf, GQ Lee, X Sun, B Etemad, LM Aboukhater, Z Hu, ZL Brumme, E Aga, RJ Bosch, Y Wen, G Namazi, C Gao, EP Acosta, RT Gandhi, JM Jacobson, D Skiest, DM Margolis, R Mitsuyasu, P Volberding, E Connick, DR Kuritzkes, MM Lederman, XG Yu, M Lichterfel, JZ Li
J. Clin. Invest., 2018-08-20;0(0):.
Species: Human
Sample Types: Plasma
-
Marital distress, depression, and a leaky gut: Translocation of bacterial endotoxin as a pathway to inflammation
Authors: JK Kiecolt-Gl, SJ Wilson, ML Bailey, R Andridge, J Peng, LM Jaremka, CP Fagundes, WB Malarkey, B Laskowski, MA Belury
Psychoneuroendocrinology, 2018-08-04;98(0):52-60.
Species: Human
Sample Types: Serum
-
The CD14 (-159 C/T) SNP is associated with sCD14 levels and allergic asthma, but not with CD14 expression on monocytes
Authors: JJ Nieto-Font, FJ Salgado, ME San-José, MJ Cruz, A Casas-Fern, MJ Gómez-Cond, L Valdés-Cua, MÁ García-Gon, P Arias, M Nogueira, FJ González-B
Sci Rep, 2018-03-07;8(1):4147.
Species: Human
Sample Types: Serum
-
The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery
Authors: A Bandera, M Masetti, M Fabbiani, M Biasin, A Muscatello, N Squillace, M Clerici, A Gori, D Trabattoni
Front Immunol, 2018-02-12;9(0):214.
Species: Human
Sample Types: Plasma
-
Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment
Authors: SJ Bissel, K Gurnsey, HP Jedema, NF Smith, G Wang, CW Bradberry, CA Wiley
Retrovirology, 2018-02-01;15(1):17.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Plasma Rich Growth Factors
-
Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable
Authors: AC Brescia, MM Simonds, SM McCahan, KE Sullivan, CD Rose
Pediatr Rheumatol Online J, 2018-01-08;16(1):3.
Species: Human
Sample Types: Synovial Fluid
-
Monocyte activation detected prior to a diagnosis of schizophrenia in the US Military New Onset Psychosis Project (MNOPP)
Authors: NS Weber, KL Gressitt, DN Cowan, DW Niebuhr, RH Yolken, EG Severance
Schizophr. Res., 2018-01-06;0(0):.
Species: Human
Sample Types: Serum
-
A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report
Authors: C Vinnard, I Manley, B Scott, M Bernui, J Adams, S Varghese, I Zentner, MA Kutzler
Tuberc Res Treat, 2017-12-21;2017(0):2140974.
Species: Human
Sample Types: Plasma
-
Elevated Neopterin Levels Predict Early Death in Older Hip-fracture Patients
Authors: M Larsen, C Bayard, H Lepetitcor, J Cohen-Bitt, V Appay, J Boddaert, D Sauce
EBioMedicine, 2017-11-06;0(0):.
Species: Human
Sample Types: Plasma
-
Reevaluation of immune activation in the era of cART and an aging HIV-infected population
Authors: LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa
JCI Insight, 2017-10-19;2(20):.
Species: Human
Sample Types: Plasma
-
Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV
Authors: MA Belury, E Bowman, J Gabriel, B Snyder, M Kulkarni, M Palettas, X Mo, JE Lake, D Zidar, SF Sieg, B Rodriguez, MP Playford, A Andrade, DR Kuritzkes, NN Mehta, MM Lederman, NT Funderburg
Pathog Immun, 2017-10-06;2(3):376-403.
Species: Human
Sample Types: Plasma
-
Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus
Authors: MR Petrara, AM Cattelan, L Sasset, R Freguja, F Carmona, S Sanavia, M Zanchetta, P Del Bianco, A De Rossi
PLoS ONE, 2017-09-19;12(9):e0185128.
Species: Human
Sample Types: Plasma
-
Quantity of alcohol drinking positively correlates with serum levels of endotoxin and markers of monocyte activation
Authors: S Liangpunsa, E Toh, RA Ross, LE Heathers, K Chandler, A Oshodi, B McGee, E Modlik, T Linton, D Mangiacarn, C Jimenez, XC Dong, L Wang, W Tu, DE Nelson
Sci Rep, 2017-06-30;7(1):4462.
Species: Human
Sample Types: Serum
-
Changes in inflammatory biomarkers in HCV-infected patients undergoing direct acting antiviral-containing regimens with or without interferon
Authors: C Mascia, S Vita, P Zuccalà, R Marocco, T Tieghi, S Savinelli, R Rossi, M Iannetta, I Pozzetto, C Furlan, F Mengoni, CM Mastroiann, V Vullo, M Lichtner
PLoS ONE, 2017-06-21;12(6):e0179400.
Species: Human
Sample Types: Plasma
-
Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease
Authors: YK Yong, HY Tan, SH Jen, EM Shankar, SK Natkunam, J Sathar, R Manikam, SD Sekaran
J Transl Med, 2017-05-31;15(1):121.
Species: Human
Sample Types: Plasma
-
Association of Anisocytosis with Markers of Immune Activation and Exhaustion in Treated HIV
Authors: SG Al-Kindi, DA Zidar, GA McComsey, CT Longenecke
Pathog Immun, 2017-05-02;2(1):138-150.
Species: Human
Sample Types: Plasma
-
Plasma IP-10 Concentrations Correlate Positively with Viraemia and Inversely with CD4 Counts in Untreated HIV Infection
Authors: K Mhandire, T Mlambo, LS Zijenah, K Duri, K Mateveke, M Tshabalala, DZ Mhandire, C Musarurwa, PT Wekare, LR Mazengera, HT Matarira, B Stray-Pede
Open AIDS J, 2017-04-26;11(0):24-31.
Species: Human
Sample Types: Plasma
-
Impact of probiotic Saccharomyces boulardii on the gut microbiome composition in HIV-treated patients: A double-blind, randomised, placebo-controlled trial
Authors: J Villar-Gar, R Güerri-Fer, A Moya, A González, JJ Hernández, E Lerma, A Guelar, L Sorli, JP Horcajada, A Artacho, G D Auria, H Knobel
PLoS ONE, 2017-04-07;12(4):e0173802.
Species: Human
Sample Types: Serum
-
Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection
Authors: RM Paris, LG Milagres, E Moysi, JF Okulicz, BK Agan, A Ganesan, C Petrovas, RA Koup
Pathog Immun, 2017-03-14;2(1):66-88.
Species: Human
Sample Types: Plasma
-
Fecal Bacterial Communities in treated HIV infected individuals on two antiretroviral regimens
Authors: S Pinto-Card, C Lozupone, O Briceño, S Alva-Herná, N Téllez, A Adriana, A Murakami-O, G Reyes-Terá
Sci Rep, 2017-03-06;7(0):43741.
Species: Human
Sample Types: Plasma
-
Interleukin-1 receptor antagonist, a biomarker of response to anti-TB treatment in HIV/TB co-infected patients
Authors: J Nouhin, P Pean, Y Madec, MF Chevalier, C Didier, L Borand, FX Blanc, D Scott-Alga, D Laureillar, L Weiss
J. Infect, 2017-02-09;0(0):.
Species: Human
Sample Types: Plasma
-
Lack of effect of Maraviroc intensification on blood and gut reservoir
Authors: Juan Tiraboschi
AIDS Res. Hum. Retroviruses, 2017-02-01;0(0):.
Species: Human
Sample Types: Plasma
-
Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders
Authors: Viktoria Johansson
Eur Arch Psychiatry Clin Neurosci, 2016-12-30;0(0):.
Species: Human
Sample Types: CSF
-
Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption
Authors: Sandra E Dross
J. Immunol, 2016-12-14;0(0):.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Plasma
-
Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication
PLoS Pathog, 2016-12-07;12(12):e1006048.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Plasma
-
Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals
Authors: Josué Pérez-Sant
J. Neurovirol, 2016-12-05;0(0):.
Species: Human
Sample Types: Plasma
-
Immune Activation and Bacterial Translocation: A Link between Impaired Immune Recovery and Frequent Visceral Leishmaniasis Relapses in HIV-Infected Patients
PLoS ONE, 2016-12-01;11(12):e0167512.
Species: Human
Sample Types: Plasma
-
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
Authors: Valentina Cecchinato
J. Immunol, 2016-11-28;0(0):.
Species: Human
Sample Types: Plasma
-
Immune Activation at Sites of HIV/TB Co-Infection Contributes to the Pathogenesis of HIV-1 Disease
PLoS ONE, 2016-11-21;11(11):e0166954.
Species: Human
Sample Types: Complex Sample Type, Plasma
-
Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes
Authors: D Margriet Ouwens
Biochim. Biophys. Acta, 2016-11-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection
Authors: M Kulkarni, E Bowman, J Gabriel, T Amburgy, E Mayne, DA Zidar, C Maierhofer, AN Turner, JA Bazan, SL Koletar, MM Lederman, SF Sieg, NT Funderburg
Open Forum Infect Dis, 2016-10-15;3(4):ofw224.
Species: Human
Sample Types: Plasma
-
Immunity in young adult survivors of childhood leukemia is more similar to elderly rather than age-matched controls: Role of cytomegalovirus (CMV)
Eur J Immunol, 2016-05-19;0(0):.
Species: Human
Sample Types: Plasma
-
HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection
PLoS ONE, 2016-04-28;11(4):e0154433.
Species: Human
Sample Types: Plasma
-
P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART
Authors: I Menkova-Ga, H Hocini, E Foucat, P Tisserand, L Bourdery, C Delaugerre, C Benne, Y Lévy, JD Lelièvre
PLoS Pathog, 2016-04-15;12(4):e1005571.
Species: Human
Sample Types: Plasma
-
Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection
Authors: D Paquin-Pro, C Ching, I Vujkovic-C, D Fadrosh, L Loh, Y Huang, M Somsouk, SV Lynch, PW Hunt, DF Nixon, D SenGupta
Mucosal Immunol, 2016-04-06;0(0):.
Species: Human
Sample Types: Plasma
-
Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange
Authors: K Crothers, I Petrache, C Wongtrakoo, PJ Lee, LM Schnapp, SA Gharib
Physiol Rep, 2016-04-01;4(8):.
Species: Human
Sample Types: Serum
-
Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.
Authors: Pandrea I, Xu C, Stock J, Frank D, Ma D, Policicchio B, He T, Kristoff J, Cornell E, Haret-Richter G, Trichel A, Ribeiro R, Tracy R, Wilson C, Landay A, Apetrei C
PLoS Pathog, 2016-01-14;12(1):e1005384.
Species: Human, Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
Sample Types: Plasma
-
Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins.
Authors: Lakritz J, Robinson J, Polydefkis M, Miller A, Burdo T
J Neuroinflammation, 2015-12-18;12(0):237.
Species: Primate
Sample Types: Plasma
-
Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities.
Authors: Ghislain M, Bastard J, Meyer L, Capeau J, Fellahi S, Gerard L, May T, Simon A, Vigouroux C, Goujard C
PLoS ONE, 2015-12-04;10(12):e0144317.
Species: Human
Sample Types: Serum
-
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption.
Authors: Rothenberger, Meghan K, Keele, Brandon, Wietgrefe, Stephen, Fletcher, Courtney, Beilman, Gregory, Chipman, Jeffrey, Khoruts, Alexande, Estes, Jacob D, Anderson, Jodi, Callisto, Samuel P, Schmidt, Thomas E, Thorkelson, Ann, Reilly, Cavan, Perkey, Katherin, Reimann, Thomas G, Utay, Netanya, Nganou Makamdop, Krystell, Stevenson, Mario, Douek, Daniel C, Haase, Ashley T, Schacker, Timothy
Proc Natl Acad Sci U S A, 2015-02-23;112(10):E1126-34.
Species: Human
Sample Types: Plasma
-
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression.
Authors: Claiborne, Daniel T, Prince, Jessica, Scully, Eileen, Macharia, Gladys, Micci, Luca, Lawson, Benton, Kopycinski, Jakub, Deymier, Martin J, Vanderford, Thomas H, Nganou-Makamdop, Krystell, Ende, Zachary, Brooks, Kelsie, Tang, Jianming, Yu, Tianwei, Lakhi, Shabir, Kilembe, William, Silvestri, Guido, Douek, Daniel, Goepfert, Paul A, Price, Matthew, Allen, Susan A, Paiardini, Mirko, Altfeld, Marcus, Gilmour, Jill, Hunter, Eric
Proc Natl Acad Sci U S A, 2015-02-17;112(12):E1480-9.
Species: Human
Sample Types: Plasma
-
Elevated plasma soluble CD14 and skewed CD16+ monocyte distribution persist despite normalisation of soluble CD163 and CXCL10 by effective HIV therapy: a changing paradigm for routine HIV laboratory monitoring?
Authors: Castley, Alison, Berry, Cassandr, French, Martyn, Fernandez, Sonia, Krueger, Romano, Nolan, David
PLoS ONE, 2014-12-29;9(12):e115226.
Species: Human
Sample Types: Plasma
-
The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.
Authors: Somsouk, Ma, Dunham, Richard, Cohen, Michelle, Albright, Rebecca, Abdel-Mohsen, Mohamed, Liegler, Teri, Lifson, Jeffrey, Piatak, Michael, Gorelick, Robert, Huang, Yong, Wu, Yuaner, Hsue, Priscill, Martin, Jeffrey, Deeks, Steven G, McCune, Joseph M, Hunt, Peter W
PLoS ONE, 2014-12-29;9(12):e116306.
Species: Human
Sample Types: Plasma
-
Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects.
Authors: Patro S, Pal S, Bi Y, Lynn K, Mounzer K, Kostman J, Davuluri R, Montaner L
J Virol, 2014-10-29;89(1):799-810.
Species: Human
Sample Types: Plasma
-
Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.
Authors: Masia M, Robledano C, Ortiz de la Tabla V, Antequera P, Lumbreras B, Hernandez I, Gutierrez F
PLoS ONE, 2014-08-18;9(8):e105442.
Species: Human
Sample Types: Plasma
-
Progressive proximal-to-distal reduction in expression of the tight junction complex in colonic epithelium of virally-suppressed HIV+ individuals.
Authors: Chung, Charlott, Alden, Stephani, Funderburg, Nicholas, Fu, Pingfu, Levine, Alan D
PLoS Pathog, 2014-06-26;10(6):e1004198.
Species: Human
Sample Types: Plasma
-
Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts.
Authors: Mandell D, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, Haret-Richter G, Xu C, Aamer H, Dufour J, Trichel A, Douek D, Keele B, Apetrei C, Pandrea I
J Virol, 2014-04-02;88(12):6778-92.
Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
Sample Types: Plasma
-
Reduced IgM levels and elevated IgG levels against oxidized low-density lipoproteins in HIV-1 infection.
Authors: Yilmaz A, Jennbacken K, Fogelstrand L
BMC Infect Dis, 2014-03-17;14(0):143.
Species: Human
Sample Types: Plasma
-
Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.
Authors: Ma, Dongzhu, Jasinska, Anna J, Feyertag, Felix, Wijewardana, Viskam, Kristoff, Jan, He, Tianyu, Raehtz, Kevin, Schmitt, Christop, Jung, Yoon, Cramer, Jennifer, Dione, Michel, Antonio, Martin, Tracy, Russell, Turner, Trudy, Robertson, David L, Pandrea, Ivona, Freimer, Nelson, Apetrei, Cristian
J Virol, 2014-03-12;88(10):5687-705.
Species: Human
Sample Types: Plasma
-
Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis.
Authors: Quon B, Ngan D, Wilcox P, Man S, Sin D
PLoS ONE, 2014-02-20;9(2):e89341.
Species: Human
Sample Types: Plasma
-
Activation of NK cells is associated with HIV-1 disease progression.
Authors: Kuri-Cervantes L, de Oca G, Avila-Rios S, Hernandez-Juan R, Reyes-Teran G
J Leukoc Biol, 2014-01-07;96(1):7-16.
Species: Human
Sample Types: Plasma
-
Dynamics of immune reconstitution and activation markers in HIV+ treatment-naive patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine.
Authors: Funderburg N, Andrade A, Chan E, Rosenkranz S, Lu D, Clagett B, Pilch-Cooper H, Rodriguez B, Feinberg J, Daar E, Mellors J, Kuritzkes D, Jacobson J, Lederman M
PLoS ONE, 2013-12-18;8(12):e83514.
Species: Human
Sample Types: Plasma
-
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
Authors: Hatano, Hiroyu, Yukl, Steven A, Ferre, April L, Graf, Erin H, Somsouk, Ma, Sinclair, Elizabet, Abdel-Mohsen, Mohamed, Liegler, Teri, Harvill, Kara, Hoh, Rebecca, Palmer, Sarah, Bacchetti, Peter, Hunt, Peter W, Martin, Jeffrey, McCune, Joseph M, Tracy, Russell, Busch, Michael, O'Doherty, Una, Shacklett, Barbara, Wong, Joseph K, Deeks, Steven G
PLoS Pathog, 2013-10-10;9(10):e1003691.
Species: Human
Sample Types: Plasma
-
Predictive value of liver enzymes and inflammatory biomarkers for the severity of liver fibrosis stage in HIV/HCV co-infected patients.
Authors: Charpentier C, Champenois K, Gervais A, Landman R, Joly V, Le Gac S, Larrouy L, Damond F, Brun-Vezinet F, Descamps D, Yazdanpanah Y
PLoS ONE, 2013-03-19;8(3):e59205.
Species: Human
Sample Types: Plasma
-
Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture.
Authors: Milani C, Katayama M, de Lyra E, Welsh J, Campos L, Brentani M, Maciel M, Roela R, del Valle P, Goes J, Nonogaki S, Tamura R, Folgueira M
BMC Cancer, 2013-03-15;13(0):119.
Species: Human
Sample Types: Cell Culture Supernates
-
Decreased IL-7 responsiveness is related to oxidative stress in HIV disease.
Authors: Kalinowska M, Bazdar D, Lederman M, Funderburg N, Sieg S
PLoS ONE, 2013-03-07;8(3):e58764.
Species: Human
Sample Types: Serum
-
SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations.
Authors: Ma, Dongzhu, Jasinska, Anna, Kristoff, Jan, Grobler, J Paul, Turner, Trudy, Jung, Yoon, Schmitt, Christop, Raehtz, Kevin, Feyertag, Felix, Martinez Sosa, Natalie, Wijewardana, Viskam, Burke, Donald S, Robertson, David L, Tracy, Russell, Pandrea, Ivona, Freimer, Nelson, Apetrei, Cristian
PLoS Pathog, 2013-01-17;9(1):e1003011.
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Plasma
-
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.
Authors: Broadhurst, Mara Jan, Ardeshir, Amir, Kanwar, Bittoo, Mirpuri, Julie, Gundra, Uma Mahe, Leung, Jacqueli, Wiens, Kirsten, Vujkovic-Cvijin, Ivan, Kim, Charlie, Yarovinsky, Felix, Lerche, Nicholas, McCune, Joseph M
Oncogene, 2012-11-15;8(11):e1003000.
Species: Human
Sample Types: Plasma
-
Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome.
Authors: Funderburg, Nicholas, Zidar, David A, Shive, Carey, Lioi, Anthony, Mudd, Joseph, Musselwhite, Laura W, Simon, Daniel I, Costa, Marco A, Rodriguez, Benigno, Sieg, Scott F, Lederman, Michael
Blood, 2012-10-11;120(23):4599-608.
Species: Human
Sample Types: Plasma
-
Relationship between microbial translocation and endothelial function in HIV infected patients.
Authors: Blodget E, Shen C, Aldrovandi G, Rollie A, Gupta S, Stein J, Dube M
PLoS ONE, 2012-08-30;7(8):e42624.
Species: Human
Sample Types: Plasma
-
CD4 T follicular helper cell dynamics during SIV infection.
J. Clin. Invest., 2012-08-27;122(9):3281-94.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Plasma
-
Altered monocyte activation markers in Tourette's syndrome: a case-control study.
Authors: Matz J, Krause DL, Dehning S, Riedel M, Gruber R, Schwarz MJ, Muller N
BMC Psychiatry, 2012-05-18;12(0):29.
Species: Human
Sample Types: Serum
-
The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis.
Authors: Ngan D, Wilcox P, Aldaabil M, Li Y, Leipsic J, Sin D, Man S
BMC Pulm Med, 2012-02-14;12(0):3.
Species: Human
Sample Types: Plasma
-
Epithelial adhesion molecules can inhibit HIV-1-specific CD8+ T-cell functions.
Authors: Streeck H, Kwon DS, Pyo A, Flanders M, Chevalier MF, Law K, Julg B, Trocha K, Jolin JS, Anahtar MN, Lian J, Toth I, Brumme Z, Chang JJ, Caron T, Rodig SJ, Milner DA, Piechoka-Trocha A, Kaufmann DE, Walker BD, Altfeld M
Blood, 2011-03-14;117(19):5112-22.
Species: Human
Sample Types: Plasma
-
Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring.
Authors: Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traore B, Doumbo S, Schollin J, Doumbo O, Montgomery SM, Sverremark-Ekstrom E
Clin. Exp. Immunol., 2010-10-05;162(3):500-9.
Species: Human
Sample Types: Milk
-
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.
Authors: Ford ES, Greenwald JH, Richterman AG
AIDS, 2010-06-19;24(10):1509-17.
Species: Human
Sample Types: Plasma
-
Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation.
Authors: Funderburg NT, Mayne E, Sieg SF
Blood, 2009-10-14;115(2):161-7.
Species: Human
Sample Types: Plasma
-
Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion.
Authors: Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, Gautam A, Coleman C, Lackner AA, Ribeiro RM, Douek DC, Apetrei C
J. Immunol., 2008-11-15;181(10):6687-91.
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Plasma
-
Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population.
Authors: Miller MA, McTernan PG, Harte AL, Silva NF, Strazzullo P, Alberti KG, Kumar S, Cappuccio FP
Atherosclerosis, 2008-07-01;203(2):494-502.
Species: Human
Sample Types: Plasma
-
Breast milk fatty acids may link innate and adaptive immune regulation: analysis of soluble CD14, prostaglandin E2, and fatty acids.
Authors: Laitinen K, Hoppu U, Hamalainen M, Linderborg K, Moilanen E, Isolauri E
Pediatr. Res., 2006-05-01;59(5):723-7.
Species: Human
Sample Types: Serum
-
CD14 is an acute-phase protein.
Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
J. Immunol., 2004-04-01;172(7):4470-9.
Species: Human
Sample Types: Serum
-
Reduced interferon gamma production and soluble CD14 levels in early life predict recurrent wheezing by 1 year of age.
Authors: Guerra S, Lohman IC, Halonen M, Martinez FD, Wright AL
Am. J. Respir. Crit. Care Med., 2003-10-02;169(1):70-6.
Species: Human
Sample Types: Serum
-
TGF-beta in human milk is associated with wheeze in infancy.
Authors: Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL
J. Allergy Clin. Immunol., 2003-10-01;112(4):723-8.
Species: Human
Sample Types: Milk
FAQs
No product specific FAQs exist for this product, however you may
View all ELISA FAQsELISA Controls
QuicKit Colorimetric Sandwich ELISAs
Supplemental ELISA Products
Reviews for Human CD14 Quantikine ELISA Kit
Average Rating: 4.6 (Based on 11 Reviews)
Have you used Human CD14 Quantikine ELISA Kit?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
I have used it for serum sample. Background was very low hence the sensitivity of the assay was brilliant. Standard curve was ran in row A and B in the figure. Blank is is A12.
Great kit frequently used. R2 on standard curve >0.999 (attached). Recommended.
Easy to follow protocol.
Plasma was isolated from blood drawn in EDTA tubes from HIV+/ART subjects and from healthy HIV- controls. sCD14 levels were measured in plasma using the Quantikine elisa Human sCD14 kit (cat# DC140). Plasma was diluted 1:200 before use in assay. Assay was carried out according to protocol provided in kit.
Figure legends:
a)Standard curve for sCD14 from which plasma sCD14 values were extrapolated.
b)Quantitated data from HIV+/ART and healthy subjects measured using the kit.
Results are expressed in ng/ml and significance calculated using unpaired Mann Whitney U-test.