Human CD39L2/ENTPD6 Antibody

Catalog #: MAB4399 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB4399
MAB4399-SP

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CD39L2/ENTPD6 Antibody Summary

Species Reactivity

Human

Specificity

Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD39, rhCD39L3, or recombinant mouse CD39 is observed.

Source

Monoclonal Mouse IgG_2B Clone # 494402

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human CD39L2/ENTPD6
Lys61-Ser484
Accession # O75354

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN)

Immunoprecipitation

25 µg/mL

Conditioned cell culture medium spiked with Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN), see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD39L2/ENTPD6

ENTPD6 (ectonucleoside triphosphate diphosphohydrolase-6), also known as CD39L2, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside 5'-triphosphates (1). Human ENTPD6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). It has a broad tissue distribution, with major expression in the heart. The amino acid sequence of human CD39L2 shares 99%, 88% and 87% identity with that of chimpanzee, mouse and dog, respectively.

References

Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.

Long Name

Ecto-Nucleoside Triphosphate Diphosphohydrolase 6

Entrez Gene IDs

955 (Human); 12497 (Mouse); 85260 (Rat)

Alternate Names

CD39 antigen-like 2; CD39L2; CD39L2NTPDase-6; CD39-like 2; dJ738P15.3; DKFZp781G2277; DKFZp781K21102; EC 3.6.1.6; ectonucleoside triphosphate diphosphohydrolase 6 (putative function); ectonucleoside triphosphate diphosphohydrolase 6 (putative); ectonucleoside triphosphate diphosphohydrolase 6; ENTPD6; FLJ36711; IL-6SAG; IL6ST2; interleukin 6 signal transducer-2; NTPD3; NTPDase 6