Human CD81 PE-conjugated Antibody
Human CD81 PE-conjugated Antibody Summary
Accession # P60033
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CD81 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD81 PE-conjugated Monoclonal Antibody (Catalog # FAB4615P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD81
CD81, also known as TAPA-1 and TM4SF4, is a widely expressed protein in the tetraspanin family. CD81 is a multifunctional protein that interacts with a variety of other molecules, including tetraspanins, and is important for organization of the plasma membrane into microdomains. CD81 facilitates B cell and T cell activation and is an integrin-binding adhesion molecule. CD81 expression on lymphocytes is altered during infection by hepatitis C virus or HIV-1 and contributes to the pathogenicity of those viruses. Human CD81 shares 92%-93% amino acid sequence identity with mouse and rat CD81.
Product Datasheets
Citations for Human CD81 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors: Q Zhang, DK Jeppesen, JN Higginboth, R Graves-Dea, VQ Trinh, MA Ramirez, Y Sohn, AC Neininger, N Taneja, ET McKinley, H Niitsu, Z Cao, R Evans, SE Glass, KC Ray, WH Fissell, S Hill, KL Rose, WJ Huh, MK Washington, GD Ayers, DT Burnette, S Sharma, LH Rome, JL Franklin, YA Lee, Q Liu, RJ Coffey
Nature Cell Biology, 2021-12-09;23(12):1240-1254.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Circulating miRNAs in Small Extracellular Vesicles Secreted by a Human Melanoma Xenograft in Mouse Brains
Authors: L Guglielmi, M Nardella, C Musa, I Cifola, M Porru, B Cardinali, I Iannetti, C Di Pietro, G Bolasco, V Palmieri, L Vilardo, N Panini, F Bonaventur, M Papi, F Scavizzi, M Raspa, C Leonetti, G Falcone, A Felsani, I D'Agnano
Cancers (Basel), 2020-06-19;12(6):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Transfer of Functional Cargo in Exomeres
Authors: Q Zhang, JN Higginboth, DK Jeppesen, YP Yang, W Li, ET McKinley, R Graves-Dea, J Ping, CM Britain, KA Dorsett, CL Hartman, DA Ford, RM Allen, KC Vickers, Q Liu, JL Franklin, SL Bellis, RJ Coffey
Cell Rep, 2019-04-04;0(0):.
Species: Human
Sample Types: Exosomes
Applications: Flow Cytometry
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