Human Contactin-6 (NP_055276) VersaClone cDNA

Catalog #: RDC1837 Datasheet / COA / SDS

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RDC1837

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Human Contactin-6 (NP_055276) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Contactin-6

Contactin-6, also known as NB-3, is a GPI-linked protein that is differentially expressed within various structures of the brain. In the cerebellum, it is presynaptically localized at synapses between excitatory glutamatergic parallel fibers and Purkinje cells. Contactin-6 knockout mice exhibit poor motor coordination. Contactin-6 associates in cis with CHL-1 and in trans with Notch-1 on oligodendrocytes. Its binding to Notch-1 triggers translocation of the Notch intracellular domain to the nucleus and promotes oligodendrogenesis.

Entrez Gene IDs

27255 (Human); 53870 (Mouse); 27256 (Rat)

Alternate Names

CNTN6; contactin 6; Contactin6; Contactin-6; MGC133256; NB3