Human DSPG3 Antibody

Catalog #: AF3110 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3110
AF3110-SP

All DSPG3 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human DSPG3 Antibody Summary

Species Reactivity

Human

Specificity

Detects human DSPG3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant mouse DSPG3 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human DSPG3
Met1-Val322
Accession # Q99645

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human DSPG3

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: DSPG3

DSPG3, also known as proteoglycan-Lb and Epiphycan, is a 95 - 100 kDa member of the class III subfamily within the SLRP (small leucine-rich proteoglycan) family. The secreted 303 aa mature segment contains multiple sites for O-linked glycanation, and seven leucine-rich repeats, flanked by N- and C-terminal cysteine-rich regions. Human DSPG3 shares 96%, 95%, 85% and 84% aa sequence identity with canine, bovine, rat and mouse DSPG3, respectively. DSPG3 is principally a component of cartilage.

Long Name

Dermatan Sulfate Proteoglycan 3

Entrez Gene IDs

1833 (Human); 13516 (Mouse)

Alternate Names

Dermatan sulfate proteoglycan 3dermatan sulphate proteoglycan 3; DSPG3; DSPG3proteoglycan-lb; Epiphycan; EPYC; PGLB; PG-Lb; Proteoglycan-Lb; SLRR3B; SLRR3Bepiphycan proteoglycan; Small chondroitin/dermatan sulfate proteoglycan