Human Endocan/ESM-1 (NP_008967) VersaClone cDNA Summary
Specifications
Product Datasheets
Background: Endocan/ESM-1
Endocan, also known as Endothelial Cell-specific Molecule-1 (ESM-1) and IGFBP-rp6, is a secreted cysteine-rich dermatan sulfate proteoglycan. It is primarily expressed by endothelial cells within the vascular network of the kidney and in the alveolar walls of the lung. Endocan expression is upregulated by TNF-alpha, IL-1 beta and LPS, and downregulated by IFN-gamma. Endocan binds LFA-1 on human lymphocytes, monocytes and Jurkat cells, inhibiting its binding to ICAM-1 and reducing LFA-1-mediated leukocyte activation. Elevated circulating Endocan levels have been reported in patients with lung cancer and severe sepsis.
FAQs
No product specific FAQs exist for this product, however you may
View all cDNA Clone FAQsReviews for Human Endocan/ESM-1 (NP_008967) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human Endocan/ESM-1 (NP_008967) VersaClone cDNA and earn rewards!
Have you used Human Endocan/ESM-1 (NP_008967) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
