Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

Name: Human ERR alpha 1/NR3B1 Antibody (Clone H5844)
Brand: R&D Systems
SKU: PP-H5844-00
Rating: 5 (1 reviews)

Catalog #: PP-H5844-00
1 Citation 1 Review Datasheet / COA / SDS

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PP-H5844-00

All ERR alpha/NR3B1 Antibodies

Product Details

Citations (1)

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Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ERR alpha 1/NR3B1 Antibody (Clone H5844) Summary

Species Reactivity

Human

Source

Monoclonal Mouse IgG2a Clone # H5844

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

Please refer to the PDF datasheet for specifications.

Immunohistochemistry

5-15 µg/mL

Immersion fixed paraffin-embedded sections of human myocardium

Immunoprecipitation

Please refer to the PDF datasheet for specifications.

Direct ELISA

Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR alpha/NR3B1

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Ushers syndrome.

Long Name

Estrogen-related Receptor alpha

Entrez Gene IDs

2101 (Human)

Alternate Names

ERR alpha; ERR1; ERR1Estrogen receptor-like 1; ERRa; ESRL1; ESRL1ERR-alpha; ESRRA; estrogen-related receptor alphaERRalpha; NR3B1; NR3B1Nuclear receptor subfamily 3 group B member 1; steroid hormone receptor ERR1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.
Authors: Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS
Proc. Natl. Acad. Sci. U.S.A., 2007-06-07;104(25):10607-12.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot