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Human FPR1 APC-conjugated Antibody

Catalog #: FAB3744A
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB3744A
Detection of FPR1 in Human Blood Monocytes by Flow Cytometry.
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Citations (1)
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Human FPR1 APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2A Clone # 350418
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
HEK293 human embryonic kidney cell line transfected with human FPR1
Met1-Lys350
Accession # NP_002020
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of FPR1 antibody in Human Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of FPR1 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human FPR1 APC-conjugated Monoclonal Antibody (Catalog # FAB3744A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPR1

FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. Human and mouse FPR1 share 73% amino acid sequence identity.

Long Name
Formyl Peptide Receptor 1
Entrez Gene IDs
2357 (Human); 14293 (Mouse); 292409 (Rat)
Alternate Names
fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPR1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor

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Citation for Human FPR1 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors
    Authors: N Novizio, R Belvedere, E Pessolano, A Tosco, A Porta, M Perretti, P Campiglia, A Filippelli, A Petrella
    Cells, 2020-12-18;9(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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