Home / FPRL1/FPR2 / Human FPRL1/FPR2 PE-conjugated Antibody

Human FPRL1/FPR2 PE-conjugated Antibody

Catalog #: FAB3479P
10 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB3479P
Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry.
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Citations (10)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human FPRL1/FPR2 PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Stains FPRL1/FPR2 transfectants but not irrelevant transfectants. It also stains monocytes and granulocytes.
Source
Monoclonal Mouse IgG2B Clone # 304405
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human FPRL1/FPR2
Met1-Met351
Accession # P25090
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of FPRL1/FPR2 antibody in Human Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human FPRL1/FPR2 PE-conjugated Monoclonal Antibody (Catalog # FAB3479P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPRL1/FPR2

FPRL1, also known as FPR2, is a 7TM protein expressed on mononuclear phagocytes and microglial cells. It interacts with formyl peptides to attract phagocytes to sites of infection and promote inflammatory reactions. FPRL1 also interacts with amyloid beta peptides and has been implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer’s disease.

Long Name
Formyl Peptide Receptor-like 1
Entrez Gene IDs
2358 (Human); 14289 (Mouse)
Alternate Names
ALXR; FMLP-R-I; FMLP-R-II; FMLPX; formyl peptide receptor 2; Formyl peptide receptor-like 1RFP; FPR2; FPR2A; FPRH1FMLP-related receptor I; FPRL1; FPRL1LXA4 receptor; HM63; HM63FPRH2; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin A4 receptor; LXA4 Receptor; LXA4RFMLP-R-I; N-formyl peptide receptor 2; RFP

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Citations for Human FPRL1/FPR2 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

10 Citations: Showing 1 - 10
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  1. Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?
    Authors: Klatte-Schulz, F;Bormann, N;Bonell, A;Al-Michref, J;Nguyen, HL;Klöckner, P;Thiele, K;Moroder, P;Seifert, M;Sawitzki, B;Wildemann, B;Duda, GN;
    Cells
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment
    Authors: L Vecchi, STS Mota, MAP Zóia, IC Martins, JB de Souza, TG Santos, AO Beserra, VP de Andrade, LR Goulart, TG Araújo
    Cells, 2022-05-20;11(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis
    Authors: Jamie D. Kraft, Robert Blomgran, Ida Bergström, Matúš Soták, Madison Clark, Alankrita Rani et al.
    The FASEB Journal
  4. Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity
    Authors: B Jundi, DH Lee, H Jeon, MG Duvall, J Nijmeh, RE Abdulnour, M Pinilla-Ve, RM Baron, J Han, J Voldman, BD Levy
    JCI Insight, 2021-08-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors
    Authors: N Novizio, R Belvedere, E Pessolano, A Tosco, A Porta, M Perretti, P Campiglia, A Filippelli, A Petrella
    Cells, 2020-12-18;9(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Annexin A1 promotes the nuclear localization of the epidermal growth factor receptor in castration-resistant prostate cancer
    Authors: STS Mota, L Vecchi, DA Alves, AO Cordeiro, GS Guimarães, E Campos-Fer, YCP Maia, BC Dornelas, SM Bezerra, VP de Andrade, LR Goulart, TG Araújo
    Int. J. Biochem. Cell Biol., 2020-08-25;127(0):105838.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease
    Authors: YC Chen, MC Lin, CH Lee, SF Liu, CC Wang, WF Fang, TY Chao, CC Wu, YF Wei, HC Chang, CC Tsen, HC Chen
    J Transl Med, 2018-03-15;16(1):69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis.
    Authors: Ho KJ, Spite M, Owens CD, Lancero H, Kroemer AH, Pande R, Creager MA, Serhan CN, Conte MS
    Am. J. Pathol., 2010-08-13;177(4):2116-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  9. Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
    Authors: McDermott DH, De Ravin SS, Jun HS
    Blood, 2010-07-08;116(15):2793-802.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  10. New insights into the phenotype of human dendritic cell populations.
    Authors: Clark GJ et al.
    Clin Transl Immunology

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