Human GPR39 APC-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: GPR39

G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane G-protein coupled glycoprotein that is a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39.

Product Datasheets

Related Research Areas

• G Protein-Coupled Receptors in Nutrition and Appetite
• G Protein-Coupled Receptors in Obesity and Related Metabolic Disorders
• Growth Hormone/IGF-I Axis
• Metabolic Peptide Hormones and Regulators
• Metabolism
• Nutrition and Appetite
• Obesity
• Peptide Hormone G Protein-Coupled Receptors