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Human HAPLN4 Antibody

Catalog #: MAB4085
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB4085
MAB4085-SP
Product Details
Citations (1)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human HAPLN4 Antibody Summary

Species Reactivity
Human
Specificity
Detects human HAPLN4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human HAPLN1 is observed.
Source
Monoclonal Mouse IgG2B Clone # 387915
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human HAPLN4
Gln30-Val402 (predicted)
Accession # Q86UW8
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human HAPLN4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: HAPLN4

Hyaluronan and Proteoglycan Link Protein 4, (HAPLN4), also known as brain link protein 2, is one of four secreted HAPLN family proteoglycans that bind hyaluronan. HAPLN4 contains one Ig-type C2-set domain and two link domains. It is predominantly expressed in brain and participates in the development of the perineuronal matrix. Human and mouse HAPLN4 share 91% aa sequence identity.

Long Name
Hyaluronan and Proteoglycan Link Protein 4
Entrez Gene IDs
404037 (Human); 330790 (Mouse)
Alternate Names
BRAL2; BRAL2KIAA1926Brain link protein 2; HAPLN4; hyaluronan and proteoglycan link protein 4; Lpr4

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Citation for Human HAPLN4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas.
    Authors: Sim H, Hu B, Viapiano MS
    J. Biol. Chem., 2009-07-24;284(39):26547-56.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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