Human Hemoglobin Antibody

Catalog # Availability Size / Price Qty
G-134-C
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews

Human Hemoglobin Antibody Summary

Species Reactivity
Human
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Human Hemoglobin
Formulation
Lyophilized from a 0.2 μm filtered solution in NaH2PO4, NaCl and Sodium Azide with Trehalose.
Label
Unconjugated
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Preparation and Storage

Reconstitution
Reconstitute with sterile PBS. If 0.5 mL of PBS is used, the antibody concentration will be 0.2 mg/mL.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Hemoglobin

Hemoglobin is a tetrameric heme-containing protein that is responsible for the transport of oxygen by red blood cells in the circulation. For most of fetal development and adulthood, hemoglobin consists of two alpha chains and two beta chains. Hemoglobin zeta (HBZ) is an approximately 15 kDa alpha chain-like protein that is produced during the first few weeks of embryogenesis until the onset of alpha chain expression. Its expression is prolonged in a0-thalassemia which is characterized by deficient alpha chain production. The Gower-1, Portland-1, and Portland-2 forms of hemoglobin consist of two zeta chains in association with either two epsilon, gamma, or beta chains, respectively. Human Hemoglobin zeta shares 79% amino acid sequence identity with mouse and rat Hemoglobin zeta.

Alternate Names
alpha one globin;alpha-1 globin;alpha-1-globin;alpha-2 globin chain;Alpha-globin;ALPHA-GLOBIN GENE;delta globin;Haemoglobin;Hb;HbA1c;hemoglobin alpha 1 globin chain;Hemoglobin alpha chain;Hemoglobin subunit alpha;hemoglobin, alpha 1; Hemoglobin

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Citations for Human Hemoglobin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS
    Authors: S Waters, MEV Swanson, BV Dieriks, YB Zhang, NL Grimsey, HC Murray, C Turner, HJ Waldvogel, RLM Faull, J An, R Bowser, MA Curtis, M Dragunow, E Scotter
    Acta neuropathologica communications, 2021-08-26;9(1):144.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  2. Reductions in brain pericytes are associated with arteriovenous malformation vascular instability
    Authors: EA Winkler, H Birk, JK Burkhardt, X Chen, JK Yue, D Guo, WC Rutledge, GF Lasker, C Partow, T Tihan, EF Chang, H Su, H Kim, BP Walcott, MT Lawton
    J. Neurosurg., 2018-12-01;0(0):1-11.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P

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