Human HepaCAM (NP_689935) VersaClone cDNA Summary
Specifications
Product Datasheets
Background: HepaCAM
HepaCAM (hepatocyte cell adhesion molecule) is a 75 kDa, type I transmembrane glycoprotein that belongs to the Ig-superfamily. It forms homodimers on the cell surface and promotes cell spreading and motility. Human HepaCAM is 382 aa in length. It contains a 206 aa extracellular domain (ECD) (aa 35-240) and a 152 aa cytoplasmic region. The ECD has two C2 Ig-like domains. There is one potential truncated isoform that shows an alternate start site at Met200. Over aa 34-242, human HepaCAM shares 99% and 98% aa sequence identity with mouse and dog HepaCAM, respectively.
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