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Human IFN-beta Antibody

Catalog #: 31410-1
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
31410-1
Product Details
Citations (2)
FAQs
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human IFN-beta Antibody Summary

Species Reactivity
Human
Specificity
Detects Human IFN‑ beta
Source
Polyclonal Rabbit Serum
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human IFN-beta
Formulation
Serum.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Neutralization

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, this product should be kept at -70 ˚C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed – the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-beta

Interferon-beta (IFN-beta), along with IFN-alpha and IFN-omega, is a member of the type I interferon family. All three type I interferons share a common cell surface receptor that is composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Type I interferons were originally described as potent anti-viral molecules produced by virally infected cells.

Long Name
Interferon beta
Entrez Gene IDs
3456 (Human); 15977 (Mouse); 24481 (Rat)
Alternate Names
Fibroblast interferon; IFB; IFBIFNB; IFF; IFNB; IFNB1; IFNbeta; IFN-beta; interferon beta; interferon, beta 1, fibroblast; MGC96956

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Citations for Human IFN-beta Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol.
    Authors: Patel MV, Ghosh M, Fahey JV, Wira CR
    PLoS ONE, 2012-04-25;7(4):e35654.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  2. The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3.
    Authors: Lee SH, Kim JS, Jun HK
    J. Immunol., 2009-05-01;182(9):5823-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization

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