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Human IFN-kappa (AAF67468.1) VersaClone cDNA

Catalog #: RDC3654 Datasheet / COA / SDS
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RDC3654
Human IFN-kappa (AAF67468.1) VersaClone cDNA
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Human IFN-kappa (AAF67468.1) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: IFN-kappa

Interferon kappa (IFN-κ) is a 24 kDa secreted, nonglycosylated polypeptide that belongs to the IFN-κ subclass of the type I interferon family of cytokines. It is expressed by macrophages in mice, and monocytes, dendritic cells and keratinocytes in human. IFN-κ induces TNF-α, IL-10 and MCP-1 production by monocytes. Mouse IFN-κ precursor is 199 amino acids (aa) in length. It contains a 21 aa signal sequence, plus a 178 aa mature region. There are two intrachain disulfide bonds plus a fifth unpaired cysteine. Mature mouse IFN-κ (aa 22 - 199) shares 68% and 30% aa identity with rat and human IFN-κ, respectively.

Long Name
Interferon kappa
Entrez Gene IDs
56832 (Human); 387510 (Mouse)
Alternate Names
IFNK; IFNkappa; IFN-kappa

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