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Human IL-10 Quantikine HS ELISA Kit

Catalog #: PHS100B
54 Citations Datasheet / COA / SDS

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PHS100B has been discontinued.
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Human IL-10 ELISA Standard Curve
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Human IL-10 Quantikine HS ELISA Kit Summary

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Scientific Data

N/A Human IL-10 ELISA Standard Curve View Larger

Human IL-10 ELISA Standard Curve

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Product Datasheet
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Preparation and Storage

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The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: IL-10

Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

Long Name:
Interleukin 10
Entrez Gene IDs:
3586 (Human); 16153 (Mouse); 25325 (Rat); 397106 (Porcine); 403628 (Canine); 102133450 (Cynomolgus Monkey); 493683 (Feline); 100715618 (Guinea Pig); 2949786 (Viral)
Alternate Names:
CSIF; CSIFMGC126450; Cytokine synthesis inhibitory factor; GVHDS; IL10; IL-10; IL10A; IL-10MGC126451; interleukin 10; interleukin-10; TGIF

Citations for Human IL-10 Quantikine HS ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

54 Citations: Showing 1 - 10
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  1. Peripheral blood CD4posCD25posFoxP3pos cells and inflammatory cytokines as biomarkers of response in rheumatoid arthritis patients treated with CTLA4-Ig
    Authors: G Elisa, B Tolusso, L Petricca, C Di Mario, MR Gigante, G Ferracciol, S Alivernini
    Arthritis Research & Therapy, 2022-06-15;24(1):143.
    Species: Human
    Sample Types: Serum
  2. Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease
    Authors: E Martín-Núñ, A Pérez-Cast, VG Tagua, C Hernández-, C Ferri, N Pérez-Delg, S Rodríguez-, P Cerro-Lópe, Á López-Cast, A Delgado-Mo, VC López-Tarr, MA Arévalo-Gó, A González-L, A Martín-Oli, CC Morales-Es, C Mora-Ferná, J Donate-Cor, JF Navarro-Go
    Scientific Reports, 2022-05-19;12(1):8422.
    Species: Human
    Sample Types: Serum
  3. Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: A randomised, double-blind, placebo-controlled trial
    Authors: C Griffen, M Duncan, J Hattersley, MO Weickert, A Dallaway, D Renshaw
    Experimental gerontology, 2021-12-09;0(0):111651.
    Species: Human
    Sample Types: Plasma
  4. Impaired Innate Immunity in Pediatric Patients Type 1 Diabetes-Focus on Toll-like Receptors Expression
    Authors: K Kurianowic, M Klatka, A Polak, A Hymos, D B?bnowska, M Podgajna, R Hrynkiewic, O Sierawska, P Nied?wiedz
    International Journal of Molecular Sciences, 2021-11-09;22(22):.
    Species: Human
    Sample Types: Plasma
  5. Association between Biomarkers of Oxidative Stress and Inflammation with Cardiac Necrosis and Heart Failure in Non-ST Segment Elevation Myocardial Infarction Patients and Various Degrees of Kidney Function
    Authors: S Roumelioti, A Veljkovic, PI Georgianos, G Lazarevic, Z Perisic, J Hadzi-Djok, V Liakopoulo, G Kocic
    Oxidative Medicine and Cellular Longevity, 2021-11-01;2021(0):3090120.
    Species: Human
    Sample Types: Serum
  6. Chemotherapy-Related Differences in Cognitive Functioning and Their Biological Predictors in Patients with Multiple Myeloma
    Authors: M Bury-Kami?, A Szudy-Szcz, A Nowaczy?sk, O Jankowska-, M Hus, K Kot
    Brain sciences, 2021-09-01;11(9):.
    Species: Human
    Sample Types: Serum
  7. Whole-Body Cryotherapy Increases the Activity of Nitric Oxide Synthase in Older Men
    Authors: M Wiecek, Z Szygula, J Gradek, J Kusmierczy, J Szymura
    Biomolecules, 2021-07-16;11(7):.
    Species: Human
    Sample Types: Plasma
  8. Comparative evaluation of inflammatory parameters and substitute insulin resistance indices in elderly women with and without type 2 diabetes mellitus
    Authors: MM Leite, MT Dutra, MVG da Costa, SS Funghetto, AO Silva, LR de Lima, ICR da Silva, MR Mota, MM Stival
    Experimental gerontology, 2021-05-03;150(0):111389.
    Species: Human
    Sample Types: Plasma
  9. Reliability and suitability of physiological exercise response and recovery markers
    Authors: T Reichel, TK Bo beta lau, J Palmowski, K Eder, R Ringseis, FC Mooren, R Walscheid, E Bothur, S Samel, T Frech, M Philippe, K Krüger
    Sci Rep, 2020-07-17;10(1):11924.
    Species: Human
    Sample Types: Plasma
  10. Effects of Pre-Sleep Whey vs. Plant-Based Protein Consumption on Muscle Recovery Following Damaging Morning Exercise
    Authors: PG Saracino, HE Saylor, BR Hanna, RC Hickner, JS Kim, MJ Ormsbee
    Nutrients, 2020-07-10;12(7):.
    Species: Human
    Sample Types: Plasma
  11. Overexpression of PD-1 on Peripheral Blood Lymphocytes in Patients with Idiopathic Pulmonary Arterial Hypertension and Its Association with High Viral Loads of Epstein-Barr Virus and Poor Clinical Parameters
    Authors: M Tomaszewsk, E Grywalska, A Tomaszewsk, P B?aszczak, M Kurzyna, J Roli?ski, G Kope?
    J Clin Med, 2020-06-24;9(6):.
    Species: Human
    Sample Types: Plasma
  12. Interferon and anti-TNF therapies differentially modulate amygdala reactivity which predicts associated bidirectional changes in depressive symptoms
    Authors: KA Davies, E Cooper, V Voon, J Tibble, M Cercignani, NA Harrison
    Mol. Psychiatry, 2020-05-26;0(0):.
    Species: Human
    Sample Types: Plasma
  13. Association between serum levels of Klotho and inflammatory cytokines in cardiovascular disease: a case-control study
    Authors: E Martín-Núñ, J Donate-Cor, C Ferri, Á López-Cast, A Delgado-Mo, C Hernández-, N Pérez-Delg, S Rodríguez-, P Cerro-Lópe, VG Tagua, C Mora-Ferná, JF Navarro-Go
    Aging (Albany NY), 2020-01-27;12(2):1952-1964.
    Species: Human
    Sample Types: Serum
  14. Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation
    Authors: AL Slusher, TM Zúñiga, EO Acevedo
    Mediators Inflamm., 2019-09-12;2019(0):2324193.
    Species: Human
    Sample Types: Plasma
  15. LIPUS vs. reaming in non-union treatment: Cytokine expression course as a tool for evaluation and differentiation of non-union therapy
    Authors: J Doll, A Moghaddam, V Daniel, B Biglari, R Heller, G Schmidmaie, TF Raven
    J Orthop, 2019-08-13;17(0):208-214.
    Species: Human
    Sample Types: Serum
  16. Vascular Adhesion Protein-1 (VAP-1) as Predictor of Radiographic Severity in Symptomatic Knee Osteoarthritis in the New York University Cohort
    Authors: E Bournazou, J Samuels, H Zhou, S Krasnokuts, J Patel, T Han, J Bencardino, L Rybak, SB Abramson, U Junker, KS Brown, M Attur
    Int J Mol Sci, 2019-05-29;20(11):.
    Species: Human
    Sample Types: Synovial Fluid
  17. Interleukin-10 as a predictor of major adverse cardiovascular events in a racially and ethnically diverse population: Multi-Ethnic Study of Atherosclerosis
    Authors: D Goldwater, A Karlamangl, SS Merkin, K Watson, T Seeman
    Ann Epidemiol, 2018-09-05;0(0):.
    Species: Human
    Sample Types: Serum
  18. Pilot study of placental tissue collection, processing, and measurement procedures for large scale assessment of placental inflammation
    Authors: LA Sjaarda, KA Ahrens, DL Kuhr, TL Holland, UR Omosigho, BT Steffen, NL Weir, HK Tollman, RM Silver, MY Tsai, EF Schisterma
    PLoS ONE, 2018-05-11;13(5):e0197039.
    Species: Human
    Sample Types: Tissue Homogenates
  19. The ties that bind: Ingroup ties are linked with diminished inflammatory immune responses and fewer mental health symptoms through less rumination
    Authors: R Ysseldyk, RJ McQuaid, OA McInnis, H Anisman, K Matheson
    PLoS ONE, 2018-04-23;13(4):e0195237.
    Species: Human
    Sample Types: Plasma
  20. Heat and Hypoxic Acclimation Increase Monocyte Heat Shock Protein 72 but Do Not Attenuate Inflammation following Hypoxic Exercise
    Authors: BJ Lee, CD Thake
    Front Physiol, 2017-10-16;8(0):811.
    Species: Human
    Sample Types: Plasma
  21. Serum and peritoneal fluid concentrations of soluble human leukocyte antigen, tumor necrosis factor alpha and interleukin 10 in patients with selected ovarian pathologies
    Authors: O Sipak-Szmi, P W?odarski, E Ronin-Walk, A Niedzielsk, B Karakiewic, S S?uczanows, M Laszczy?sk, W Malinowski
    J Ovarian Res, 2017-04-04;10(1):25.
    Species: Human
    Sample Types: Serum
  22. Annexin A1 in blood mononuclear cells from patients with coronary artery disease: Its association with inflammatory status and glucocorticoid sensitivity
    Authors: I Bergström, AK Lundberg, S Jönsson, E Särndahl, J Ernerudh, L Jonasson
    PLoS ONE, 2017-03-22;12(3):e0174177.
    Species: Human
    Sample Types: Plasma
  23. Aberrant expression of interleukin-10 in rheumatoid arthritis: Relationship with IL10 haplotypes and autoantibodies
    Authors: J Hernández-, E Oregón-Rom, M Vázquez-Vi, S García-Are, Y Valle, JR Padilla-Gu, IV Román-Fern, CA Palafox-Sá, GE Martínez-B, JF Muñoz-Vall
    Cytokine, 2017-02-27;95(0):88-96.
    Species: Human
    Sample Types: Serum
  24. Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
    Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
    ESC Heart Fail, 2016-08-31;4(1):56-65.
    Species: Human
    Sample Types: Serum
  25. Genome-Wide Association Study Identifies That the ABO Blood Group System Influences Interleukin-10 Levels and the Risk of Clinical Events in Patients with Acute Coronary Syndrome.
    Authors: Johansson A, Alfredsson J, Eriksson N, Wallentin L, Siegbahn A
    PLoS ONE, 2015-11-24;10(11):e0142518.
    Species: Human
    Sample Types: Plasma
  26. Acute phase IL-10 plasma concentration associates with the high risk sources of cardiogenic stroke.
    Authors: Arponen O, Muuronen A, Taina M, Sipola P, Hedman M, Jakala P, Vanninen R, Pulkki K, Mustonen P
    PLoS ONE, 2015-04-29;10(4):e0120910.
    Species: Human
    Sample Types: Plasma
  27. Mucosal effects of tenofovir 1% gel.
    Authors: Hladik F, Burgener A, Ballweber L, Gottardo R, Vojtech L, Fourati S, Dai J, Cameron M, Strobl J, Hughes S, Hoesley C, Andrew P, Johnson S, Piper J, Friend D, Ball T, Cranston R, Mayer K, McElrath M, McGowan I
    Elife, 2015-02-03;4(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Psychological stress exerts effects on pathogenesis of hepatitis B via type-1/type-2 cytokines shift toward type-2 cytokine response.
    Authors: He Y, Gao H, Li X, Zhao Y
    PLoS ONE, 2014-08-21;9(8):e105530.
    Species: Human
    Sample Types: Plasma
  29. The impact of two different transfusion strategies on patient immune response during major abdominal surgery: a preliminary report.
    Authors: Theodoraki K, Markatou M, Rizos D, Fassoulaki A
    J Immunol Res, 2014-04-03;2014(0):945829.
    Species: Human
    Sample Types: Plasma
  30. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
    Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
    Obesity (Silver Spring), 2011-09-08;19(11):2130-6.
    Species: Human
    Sample Types: Plasma
  31. Whole-Body UVB Irradiation during Allogeneic Hematopoietic Cell Transplantation Is Safe and Decreases Acute Graft-versus-Host Disease.
    Authors: Kreutz M, Karrer S, Hoffmann P
    J. Invest. Dermatol., 2011-08-18;132(1):179-87.
    Species: Human
    Sample Types: Serum
  32. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise.
    Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
    PLoS ONE, 2011-07-28;6(7):e22748.
    Species: Human
    Sample Types: Plasma
  33. SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
    Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
    Diabetes, 2010-01-27;59(4):829-35.
    Species: Human
    Sample Types: Plasma
  34. Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects.
    Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
    Atherosclerosis, 2009-12-02;210(2):536-41.
    Species: Human
    Sample Types: Plasma
  35. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria.
    Authors: Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, Opelz G
    Transplantation, 2009-11-15;88(9):1109-16.
    Species: Human
    Sample Types: Urine
  36. Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
    Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
    Cytokine, 2009-07-24;47(3):206-13.
    Species: Human
    Sample Types: Plasma
  37. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
    Diabetes Care, 2008-12-17;32(3):486-92.
    Species: Human
    Sample Types: Serum
  38. Two large preoperative doses of erythropoietin do not reduce the systemic inflammatory response to cardiac surgery.
    Authors: Poulsen TD, Andersen LW, Steinbruchel D, Gotze JP, Jorgensen OS, Olsen NV
    J. Cardiothorac. Vasc. Anesth., 2008-10-22;23(3):316-23.
    Species: Human
    Sample Types: Plasma
  39. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
    Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
    Clin. Exp. Immunol., 2008-05-05;153(2):196-204.
    Species: Human
    Sample Types: Serum
  40. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?
    Authors: Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF
    Ann. Surg., 2008-02-01;247(2):320-6.
    Species: Human
    Sample Types: Plasma
  41. Duffy antigen modifies the chemokine response in human endotoxemia.
    Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B
    Crit. Care Med., 2008-01-01;36(1):159-65.
    Species: Human
    Sample Types: Plasma
  42. Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
    Authors: Koivisto H, Hietala J, Anttila P, Niemela O
    Dig. Dis. Sci., 2007-06-28;53(2):500-5.
    Species: Human
    Sample Types: Serum
  43. Anti-inflammatory cytokines in gingival crevicular fluid in patients with periodontitis and rheumatoid arthritis: a preliminary report.
    Authors: Bozkurt FY, Yetkin Ay Z, Berker E, Tepe E, Akkus S
    Cytokine, 2006-09-18;35(3):180-5.
    Species: Human
    Sample Types:
  44. The activity of N-acetyl-beta-D-glucosaminidase and tumor necrosis factor-alpha at early stage of diabetic retinopathy development in type 1 diabetes mellitus children.
    Authors: Mysliwiec M, Zorena K, Balcerska A, Mysliwska J, Lipowski P, Raczynska K
    Clin. Biochem., 2006-04-05;39(8):851-6.
    Species: Human
    Sample Types: Serum
  45. Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic disease.
    Authors: Theurl I, Mattle V, Seifert M, Mariani M, Marth C, Weiss G
    Blood, 2006-01-24;107(10):4142-8.
    Species: Human
    Sample Types: Serum
  46. Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia.
    Authors: Leitner JM, Firbas C, Mayr FB, Reiter RA, Steinlechner B, Jilma B
    Clin. Pharmacol. Ther., 2006-01-01;79(1):23-34.
    Species: Human
    Sample Types: Plasma
  47. Interleukin-8, monocyte chemoattractant protein-1 and IL-10 in the vitreous fluid of patients with proliferative diabetic retinopathy.
    Authors: Hernandez C, Segura RM, Fonollosa A, Carrasco E, Francisco G, Simo R
    Diabet. Med., 2005-06-01;22(6):719-22.
    Species: Human
    Sample Types: Vitreous Humor
  48. Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
    Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
    Microbes Infect., 2005-02-24;7(3):427-36.
    Species: Human
    Sample Types: Serum
  49. Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection.
    Authors: Sadeghi M, Daniel V, Naujokat C, Wiesel M, Hergesell O, Opelz G
    Transpl. Int., 2005-02-01;18(2):177-85.
    Species: Human
    Sample Types: Plasma
  50. Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.
    Authors: Jensen J, Krakauer M, Sellebjerg F
    Cytokine, 2005-01-07;29(1):24-30.
    Species: Human
    Sample Types: Plasma
  51. Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease.
    Authors: Schieffer B, Bunte C, Witte J, Hoeper K, Boger RH, Schwedhelm E, Drexler H
    J. Am. Coll. Cardiol., 2004-07-21;44(2):362-8.
    Species: Human
    Sample Types: Serum
  52. Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors.
    Authors: Alter P, Maisch B
    Z Kardiol, 2004-07-01;93(7):524-32.
    Species: Human
    Sample Types: Serum
  53. Immunodetection of a hepatitis C virus (HCV) antigen and Thl/Th2 cytokines in cerebrospinal fluid of meningitis patients.
    Authors: Attallah AM, Ibrahim GG
    J Immunoassay Immunochem, 2004-01-01;25(4):313-20.
    Species: Human
    Sample Types: Serum
  54. Low levels of interferon-gamma in nasal fluid accompany raised levels of T-helper 2 cytokines in children with ongoing allergic rhinitis.
    Authors: Benson M, Strannegard IL, Wennergren G, Strannegard O
    Pediatr Allergy Immunol, 2000-02-01;11(1):20-8.
    Species: Human
    Sample Types: Nasal Lavage Fluid

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