Human INSRR Biotinylated Antibody

Catalog #: BAF3055 Datasheet / COA / SDS

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BAF3055

All INSRR Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human INSRR Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human INSRR in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human INSR is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human INSRR

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: INSRR

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family. It is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. A ligand for INSRR has not yet been identified. The extracellular domain of human INSRR shares approximately 90% amino acid sequence homology with the mouse protein.

Long Name

Insulin Receptor-related Receptor

Entrez Gene IDs

3645 (Human); 23920 (Mouse)

Alternate Names

EC 2.7.10; EC 2.7.10.1; INSRR; insulin receptor-related protein; insulin receptor-related receptor; IRR; IRRIR-related receptor