Human Integrin beta 8 (NP_002205) VersaClone cDNA

Catalog #: RDC0970 Datasheet / COA / SDS

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RDC0970

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Human Integrin beta 8 (NP_002205) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Rat

Product Datasheets

Product Datasheet

COA

SDS

Background: Integrin beta 8

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

Entrez Gene IDs

3696 (Human); 320910 (Mouse); 362800 (Rat)

Alternate Names

Integrin beta 8; integrin beta-8; integrin, beta 8; ITGB8