Home / L-Selectin/CD62L / Human L-Selectin/CD62L Fluorescein-conjugated Antibody

Human L-Selectin/CD62L Fluorescein-conjugated Antibody

Catalog #: BBA33
6 Citations Datasheet / COA / SDS

Discontinued Product

BBA33 has been discontinued.
View all L-Selectin/CD62L products.
R&D Systems Antibodies
1 Image
Product Details
Citations (6)
FAQs
Reviews
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human L-Selectin/CD62L Fluorescein-conjugated Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG1 Clone # 4G8
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: L-Selectin/CD62L

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

Entrez Gene IDs
6402 (Human); 20343 (Mouse); 29259 (Rat); 102142895 (Cynomolgus Monkey)
Alternate Names
CD62L antigen; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LAM1LECAM1; LECAM1; LEU8; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LNHRTQ1; LSEL; L-Selectin; LYAM1; Lyam-1; LYAM1CD62 antigen-like family member L; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L; SELL; TQ1

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for Human L-Selectin/CD62L Fluorescein-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

6 Citations: Showing 1 - 6
Filter your results:

Filter by:

  1. Inhibition of pre-B cell colony-enhancing factor (PBEF/NAMPT/visfatin) decreases the ability of human neutrophils to generate reactive oxidants but does not impair bacterial killing.
    Authors: Roberts, Kate J, Cross, Andrew, Vasieva, Olga, Moots, Robert J, Edwards, Steven W
    J Leukoc Biol, 2013-06-26;94(3):481-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. RNA-seq reveals activation of both common and cytokine-specific pathways following neutrophil priming.
    Authors: Wright H, Thomas H, Moots R, Edwards S
    PLoS ONE, 2013-03-06;8(3):e58598.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Anti-inflammatory and anti-allergic activities of Pentaherb formula, Moutan Cortex (Danpi) and gallic acid.
    Authors: Liu K, Hu S, Chan B, Wat E, Lau C, Hon K, Fung K, Leung P, Hui P, Lam C, Wong C
    Molecules, 2013-02-25;18(3):2483-500.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation.
    Authors: Wong CK, Hu S, Cheung PF
    Am. J. Respir. Cell Mol. Biol., 2009-10-20;43(3):305-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche.
    Authors: Raffaghello L, Bianchi G, Bertolotto M, Montecucco F, Busca A, Dallegri F, Ottonello L, Pistoia V
    Stem Cells, 2007-10-11;26(1):151-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct.
    Authors: Dreier T, Baeuerle PA, Fichtner I, Grun M, Schlereth B, Lorenczewski G, Kufer P, Lutterbuse R, Riethmuller G, Gjorstrup P, Bargou RC
    J. Immunol., 2003-04-15;170(8):4397-402.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human L-Selectin/CD62L Fluorescein-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human L-Selectin/CD62L Fluorescein-conjugated Antibody and earn rewards!

Have you used Human L-Selectin/CD62L Fluorescein-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review