Human Legumain (NP_005597.3) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC3313
Human Legumain (NP_005597.3) VersaClone cDNA
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Human Legumain (NP_005597.3) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: Legumain/Asparaginyl Endopeptidase

Legumain is a lysosomal cysteine protease that plays a pivotal role in the endosomal/lysosomal degradation system. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Also known as Asparaginyl Endopeptidase, it specifically cleaves peptide bonds with Asn or Asp at the P1 position.

Entrez Gene IDs
5641 (Human); 19141 (Mouse)
Alternate Names
AEP; Asparaginyl Endopeptidase; cysteine protease 1; Legumain; LGMN; LGMN1; Protease, cysteine 1; protease, cysteine, 1 (legumain); PRSC1EC 3.4.22.34

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