Human MMP-25/MT6-MMP Antibody

Catalog # Availability Size / Price Qty
MAB1142
MAB1142-SP
Product Details
Citations (1)
FAQs
Supplemental Products
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Human MMP-25/MT6-MMP Antibody Summary

Species Reactivity
Human
Specificity
Detects human MMP‑25/MT6-MMP in Western blots.
Source
Monoclonal Mouse IgG1 Clone # 141808
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human MMP‑25/MT6-MMP
Pro314-Cys508
Accession # Q9NPA2
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Human MMP‑25/MT6-MMP
Flow Cytometry
2.5 µg/106 cells
Human whole blood granulocytes
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MMP-25/MT6-MMP

MMP-25, also known as MT6-MMP or Leukolysin, is a GPI-linked protease expressed by neutrophils. MMP-25 cleaves collagen type 4, gelatin, fibronectin and fibrin.

Long Name
Matrix Metalloproteinase 25/Membrane Type 6 MMP
Entrez Gene IDs
64386 (Human)
Alternate Names
Leukolysin; matrix metallopeptidase 25; matrix metallopeptidase-like 1; matrix metalloproteinase 20; matrix metalloproteinase 25; matrix metalloproteinase-25; matrix metalloproteinase-like 1; membrane-type 6 matrix metalloproteinase; membrane-type matrix metalloproteinase 6; membrane-type-6 matrix metalloproteinase; MMP20; MMP20A; MMP25; MMP-25; MMPL1; MT6MMP; MT6-MMP; MT-MMP 6; MTMMP6; MT-MMP6

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Citation for Human MMP-25/MT6-MMP Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25).
    Authors: Zhao H, Sohail A, Sun Q, Shi Q, Kim S, Mobashery S, Fridman R
    J. Biol. Chem., 2008-10-20;283(50):35023-32.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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