Human MMP-28 (NP_077278) VersaClone cDNA

Catalog #: RDC2001 Datasheet / COA / SDS

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RDC2001

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Human MMP-28 (NP_077278) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: MMP-28

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

Long Name

Matrix Metalloproteinase 28

Entrez Gene IDs

79148 (Human); 118453 (Mouse); 303384 (Rat)

Alternate Names

EC 3.4.24; EC 3.4.24.-; Epilysin; matrix metallopeptidase 28; matrix metalloproteinase 28; MM28; MMP25; MMP28; MMP-28; MMP-28MMP-25; putative MMP28 gene product

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