Human/Mouse Brachyury Antibody Summary
Ser2-Glu202
Accession # O15178
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of Recombinant Human Brachyury by Western Blot. Western blot shows 10 ng of Recombinant Human Brachyury (amino acids Ser2-Glu202) and Recombinant Human TBX6. PVDF Membrane was probed with 0.1 µg/mL of Goat Anti-Human/Mouse Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). A specific band was detected for Brachyury at approximately 26 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.
Detection of Human Brachyury by Western Blot. Western blot shows lysates of NCI‑H460 human large cell lung carcinoma cell line and MCF 10A human breast epithelial cell line (negative control). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for Brachyury at approximately 50 kDa (as indicated). GAPDH (AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1.
Brachyury in Differentiated Human Embryonic Stem Cells. Brachyury was detected in immersion fixed differentiated human embryonic stem cells using 10 µg/mL Goat Anti-Human Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) for 3 hours at room temperature. Cells were stained (green) and counter-stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Brachyury in BG01V Human Stem Cells. Brachyury was detected in immersion fixed BG01V human embryonic stem cells differentiated into mesoderm using Goat Anti-Human Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the Northern-Lights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counter-stained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Brachyury in Embryonic Mouse Notochord. Brachyury was detected in immersion fixed frozen sections of embryonic mouse notochord (E9.5) using 10 µg/mL Goat Anti-Human Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) overnight at 4 °C. Tissue was stained with the Northern-Lights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counter-stained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Detection of Brachyury-regulated Genes by Chromatin Immunoprecipitation. Mesoderm-differentiated BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. Brachyury/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (MAG999) and DNA was purified using chelating resin solution. TheVEGFpromoter was detected by standard PCR.
Detection of Brachyury in NCI-H460 cells by Flow Cytometry. NCI-H460 cells were stained with Goat Anti-Human/Mouse Brachyury Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2085, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules.
Detection of Human Brachyury by Immunocytochemistry/Immunofluorescence Generation and characterization of systemic lupus erythematosus (SLE)‐specific human‐induced pluripotent stem cells (hiPSCs). (A) Dermal fibroblasts derived from patient with SLE were reprogrammed into iPSCs using Sendai virus vectors and three clones (#1, #2 and #3) were characterized. RT‐PCR confirms the loss of transgenes in hiPSCs‐SLE (lanes 1, 2 and 3), presence (lane 4) in infected fibroblasts (ipF‐SLE) and absence of Sendai viral transgenes in parental fibroblasts (pF‐SLE) (lane 5). Full‐length gels are presented in File S2. (B) The hiPSCs‐SLE colonies expressed alkaline phosphatase. Scale bar, 500 μm. (C) RT‐qPCR analysis of pluripotency genes OCT4, NANOG, SOX2 and REX1 was performed in fibroblasts and in hiPSCs derived from patient with SLE. All expression values are normalized to GAPDH and relative donor fibroblasts. Data are mean ± SEM and all statistical analysis was made between hiPSCs‐SLE clones and relative fibroblasts by Student's t test showing P‐values ≤ .05 in each comparison. (D) PluriTest assays combines novelty score (blue) on x‐axis and pluripotency score (red) on y‐axis. hiPSCs‐SLE localize in the red cloud suggesting the empirical distribution of pluripotent cells compared to non‐pluripotent blue cloud. (E) Representative images of M‐FISH staining show normal karyotypes of hiPSCs‐SLE clones. (F) Immunofluorescence analysis of pluripotent stem cell markers Nanog (green), Oct4 (red) and co‐staining with DAPI (blue) in hiPSCs‐SLE. Scale bar, 50 μm. (G) Representative images of floating and adherent EBs derived from hiPSCs‐SLE at differentiation day 8 and 18, respectively. Scale bar, 500 μm. (H) RT‐qPCR results confirm the capability of hiPSCs‐SLE to differentiate into all three germ layers. The expression levels of GATA4, HAND1 and PAX6 in EBs are relative to undifferentiated hiPSCs. All expression values are normalized to GAPDH and relative hiPSCs. Data are mean ± SEM and all statistical analysis was made between EBs‐SLE and relative hiPSCs‐SLE clones by Student's t test showing P‐values ≤ .05 in each comparison. (I) Immunostaining of Otx2 (ectoderm marker), Sox17 (endoderm marker), Brachyury (mesoderm marker) and co‐staining with DAPI (blue) in EBs derived from hiPSCs‐SLE. Scale bar, 50 μm Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31536674), licensed under a CC-BY license. Not internally tested by R&D Systems.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Brachyury
Brachyury is the founding member of the T-box family of transcription factors, which is characterized by the N-terminal conserved DNA-binding T-domain. Brachyury is required in the early determination and differentiation of mesoderms. Human brachyury molecule shares 90% homology with mouse brachyury.
Product Datasheets
Product Specific Notices
BG01V cells are licensed from ViaCyte, Inc.Citations for Human/Mouse Brachyury Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency
Authors: Amar M. Singh, Yuhua Sun, Li Li, Wenjuan Zhang, Tianming Wu, Shaying Zhao et al.
Stem Cell Reports
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Distinct Molecular Trajectories Converge to Induce Naive Pluripotency
Authors: Hannah T. Stuart, Giuliano G. Stirparo, Tim Lohoff, Lawrence E. Bates, Masaki Kinoshita, Chee Y. Lim et al.
Cell Stem Cell
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Kinases of the Focal Adhesion Complex Contribute to Cardiomyocyte Specification
Authors: Sacha Robert, Marcus Flowers, Brenda M. Ogle
International Journal of Molecular Sciences
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Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor
Authors: Antigoni Gogolou, Celine Souilhol, Ilaria Granata, Filip J Wymeersch, Ichcha Manipur, Matthew Wind et al.
eLife
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Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution
Authors: Cowan CS, Renner M, De Gennaro M et al.
Cell
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Generation of an induced pluripotent stem cell line (NCHi010-A) from a 6-year-old female with Down syndrome and without congenital heart disease
Authors: Yu Y, Alonzo M, Ye S et al.
Stem Cell Research
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Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells
Authors: Yanxiao Zhang, Ting Li, Sebastian Preissl, Maria Luisa Amaral, Jonathan D. Grinstein, Elie N. Farah et al.
Nature Genetics
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Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions
Authors: Xiaoping Bao, Xiaojun Lian, Tongcheng Qian, Vijesh J. Bhute, Tianxiao Han, Sean P. Palecek
Nature Protocols
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Spatial Stem Cell Fate Engineering via Facile Morphogen Localization
Authors: Jin G, Floy ME, Simmons AD et al.
Advanced healthcare materials
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Rat post-implantation epiblast-derived pluripotent stem cells produce functional germ cells
Authors: Kenyu Iwatsuki, Mami Oikawa, Hisato Kobayashi, Christopher A. Penfold, Makoto Sanbo, Takuya Yamamoto et al.
Cell Reports Methods
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Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells
Authors: Josefina Inés del Mármol, Kouki K Touhara, Gist Croft, Roderick MacKinnon
eLife
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Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
Authors: Zachary T. Olmsted, Cinzia Stigliano, Annalisa Scimemi, Tatiana Wolfe, Jose Cibelli, Philip J. Horner et al.
iScience
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An in vitro stem cell model of human epiblast and yolk sac interaction
Authors: KM Mackinlay, BA Weatherbee, V Souza Rosa, CE Handford, G Hudson, T Coorens, LV Pereira, S Behjati, L Vallier, MN Shahbazi, M Zernicka-G
Elife, 2021-08-17;10(0):.
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Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells
Authors: Marina Gattiglio, Michelle Protzek, Christian Schröter
Biology Open
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Human axial progenitors generate trunk neural crest cells in vitro
Authors: Thomas JR Frith, Ilaria Granata, Matthew Wind, Erin Stout, Oliver Thompson, Katrin Neumann et al.
eLife
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Geminin is required for Hox gene regulation to pattern the developing limb
Authors: Emily M.A. Lewis, Savita Sankar, Caili Tong, Ethan S. Patterson, Laura E. Waller, Paul Gontarz et al.
Developmental Biology
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Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded
Authors: Michael P. Meers, Derek H. Janssens, Steven Henikoff
Molecular Cell
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A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells
Authors: Martin Müller, Jana Schröer, Ninel Azoitei, Tim Eiseler, Wendy Bergmann, Ralf Köhntop et al.
Scientific Reports
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Assessing the bipotency of in vitro-derived neuromesodermal progenitors
Authors: Anestis Tsakiridis, Valerie Wilson
F1000Research
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Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse
Authors: Ioanna Mastromina, Laure Verrier, Joana Clara Silva, Kate G. Storey, J. Kim Dale
Development
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NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis
Authors: Tessier S, Madhu V, Johnson ZI et al.
Dev. Biol.
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Identification of repurposed small molecule drugs for chordoma therapy
Authors: Menghang Xia, Ruili Huang, Srilatha Sakamuru, David Alcorta, Ming-Hsuang Cho, Dae-Hee Lee et al.
Cancer Biology & Therapy
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Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction
Authors: Kylie S. Foo, Miia L. Lehtinen, Chuen Yan Leung, Xiaojun Lian, Jiejia Xu, Wendy Keung et al.
Molecular Therapy
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BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity
Authors: Richard H Row, Amy Pegg, Brian A Kinney, Gist H Farr, Lisa Maves, Sally Lowell et al.
eLife
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A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation
Authors: André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral et al.
eLife
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Prediction and control of symmetry breaking in embryoid bodies by environment and signal integration
Authors: Naor Sagy, Shaked Slovin, Maya Allalouf, Maayan Pour, Gaya Savyon, Jonathan Boxman et al.
Development
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Generation and validation of APOE knockout human iPSC-derived cerebral organoids
Authors: Yuka A. Martens, Siming Xu, Richard Tait, Gary Li, Xinping C. Zhao, Wenyan Lu et al.
STAR Protocols
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Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration
Authors: Francesco Antonica, Lorenzo Carlo Orietti, Richard Lester Mort, Magdalena Zernicka-Goetz
Developmental Biology
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CRISPR-Cas9-mediated loss of function of beta -catenin attenuates intervertebral disc degeneration
Authors: Yunshan Fan, Lan Zhao, Yumei Lai, Ke Lu, Jian Huang
Molecular Therapy - Nucleic Acids
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Genome-wide CRISPR screen identifies ZIC2 as an essential gene that controls the cell fate of early mesodermal precursors to human heart progenitors
Authors: Jiejia Xu, Chikai Zhou, Kylie S. Foo, Ran Yang, Yao Xiao, Kristine Bylund et al.
Stem Cells
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Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak
Authors: Kenzo Ivanovitch, Pablo Soro-Barrio, Probir Chakravarty, Rebecca A. Jones, Donald M. Bell, S. Neda Mousavy Gharavy et al.
PLOS Biology
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Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer
Authors: Filipe Pinto, Nelma Pértega-Gomes, José R. Vizcaíno, Raquel P. Andrade, Flavio M. Cárcano, Rui Manuel Reis
Oncotarget
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A method for human teratogen detection by geometrically confined cell differentiation and migration
Authors: Jiangwa Xing, Yi-Chin Toh, Shuoyu Xu, Hanry Yu
Scientific Reports
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Generation of fourteen isogenic cell lines for Parkinsons disease-associated leucine-rich repeat kinase (LRRK2)
Authors: Beylina A, Langston R, Rosen D et al.
Stem Cell Research
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Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c–SIRT2 axis
Authors: Young Cha, Min-Joon Han, Hyuk-Jin Cha, Janet Zoldan, Alison Burkart, Jin Hyuk Jung et al.
Nature Cell Biology
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Efficient differentiation of human primordial germ cells through geometric control reveals a key role for Nodal signaling
Authors: Kyoung Jo, Seth Teague, Bohan Chen, Hina Aftab Khan, Emily Freeburne, Hunter Li et al.
eLife
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Putative oncogene Brachyury ( T ) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT
Authors: Jianjian Zhu, Kin Ming Kwan, Susan Mackem
Proceedings of the National Academy of Sciences
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The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos
Authors: Sophie M Morgani, Jie Su, Jennifer Nichols, Joan Massagué, Anna-Katerina Hadjantonakis
eLife
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TFAP2C regulates transcription in human naive pluripotency by opening enhancers
Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
Nat. Cell Biol., 2018-04-25;20(5):553-564.
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Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation
Authors: Philipp Andre, Hai Song, Wantae Kim, Andreas Kispert, Yingzi Yang
Development
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Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase.
Authors: Tan, Frederic, Elowitz, Michael
Proc Natl Acad Sci U S A, 2014-04-14;111(17):E1740-8.
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Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs
Authors: Y Lin, H Liu, M Klein, J Ostrominsk, SG Hong, RC Yada, G Chen, K Navarengom, R Schwartzbe, H San, ZX Yu, C Liu, K Linask, J Beers, L Qiu, CE Dunbar, M Boehm, J Zou
Sci Rep, 2018-04-12;8(1):5907.
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Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells
Authors: Garreta E, Prado P, Tarantino C et al.
Nature Materials
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Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells
Authors: Idse Heemskerk, Kari Burt, Matthew Miller, Sapna Chhabra, M Cecilia Guerra, Lizhong Liu et al.
eLife
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Elimination of Mutant mtDNA by an Optimized mpTALEN Restores Differentiation Capacities of Heteroplasmic MELAS-iPSCs
Authors: Yahata N, Boda H, Hata R
Molecular therapy. Methods & clinical development
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Growth and differentiation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels
Authors: Niall J. Treacy, Shane Clerkin, Jessica L. Davis, Ciarán Kennedy, Aline F. Miller, Alberto Saiani et al.
Bioactive Materials
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Glutamine-dependent signaling controls pluripotent stem cell fate
Authors: Vivian Lu, Irena J. Roy, Alejandro Torres, James H. Joly, Fasih M. Ahsan, Nicholas A. Graham et al.
Developmental Cell
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A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects
Authors: Geetika Sahni, Shu‐Yung Chang, Jeremy Teo Choon Meng, Jerome Zu Yao Tan, Jean Jacques Clement Fatien, Carine Bonnard et al.
Advanced Science
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Generation of two isogenic patient-derived human-induced pluripotent stem cell clones with 6q27 deletion
Authors: Bianchini, L;Sieber, L;Hammad, R;Schäfer, R;Kutscher, LM;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of an induced pluripotent stem cell (iPSC) line (EXSURGi001-A) from a patient homozygous for the p.Ala165Thr mutation in the MTARC1 gene
Authors: Tang, P;Keshi, E;Wilken, S;Wutsdorff, L;Mougnekabol, J;Pratschke, J;Sauer, IM;Haep, N;
Stem cell research
Species: Human
Sample Types: Embryoid Bodies
Applications: Immunohistochemistry -
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells
Authors: McCreery, KP;Stubb, A;Stephens, R;Fursova, NA;Cook, A;Kruse, K;Michelbach, A;Biggs, LC;Keikhosravi, A;Nykänen, S;Hydén-Granskog, C;Zou, J;Lackmann, JW;Niessen, CM;Vuoristo, S;Miroshnikova, YA;Wickström, SA;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells, Embryo
Applications: Immunohistochemistry, Immunocytochemistry -
Non-apical mitoses contribute to cell delamination during mouse gastrulation
Authors: Despin-Guitard, E;Rosa, VS;Plunder, S;Mathiah, N;Van Schoor, K;Nehme, E;Merino-Aceituno, S;Egea, J;Shahbazi, MN;Theveneau, E;Migeotte, I;
Nature communications
Species: Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: Immunohistochemistry, Immunocytochemistry -
Generation of an induced pluripotent stem cell line (NCHi016-A) from a 5-year-old female with pulmonary atresia with intact ventricular septum and one-and-half ventricle palliation
Authors: Qin, H;Yu, Y;Ye, S;Alonzo, M;Garg, V;Zhao, MT;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of two induced pluripotent stem cell lines from patients with Li-Fraumeni Syndrome carrying TP53 mutation
Authors: Sun, J;Ren, L;Canel Rivero, G;Xu, L;Ladabaum, U;C Wu, J;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of two induced pluripotent stem cell lines from patients with Williams syndrome
Authors: Dai, Y;Zhu, W;Flores Banuelos, AG;Li, J;Mukherjee, S;Algaze, C;Wu, JC;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Temporally resolved single cell transcriptomics in a human model of amniogenesis
Authors: Sekulovski, N;Carleton, AE;Rengarajan, AA;Lin, CW;Juga, LN;Whorton, AE;Schmidt, JK;Golos, TG;Taniguchi, K;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Organoid
Applications: Immunocytochemistry -
Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids
Authors: Jo, K;Liu, ZY;Patel, G;Yu, Z;Yao, L;Teague, S;Johnson, C;Spence, J;Heemskerk, I;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Control of epiblast cell fate by mechanical cues
Authors: Guillot, C;Djeffal, Y;Serra, M;Pourquié, O;
bioRxiv : the preprint server for biology
Species: Chicken
Sample Types: Embryo
Applications: Immunohistochemistry -
CRISPR/Cas9-based GLA knockout to generate the female Fabry disease human induced pluripotent stem cell line MHHi001-A-15
Authors: Juchem, M;Lehmann, N;Behrens, YL;Bär, C;Thum, T;Hoepfner, J;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of iPSC line NCHi015-A from a patient with truncus arteriosus carrying heterozygous variants in KMT2D and NOTCH1
Authors: Wang, J;Bering, J;Alonzo, M;Ye, S;Texter, K;Garg, V;Zhao, MT;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a human induced pluripotent stem cell line from a patient with GM3 synthase deficiency using self-replicating RNA vector
Authors: Tonin, R;Feo, F;Falliano, S;Giunti, L;Calamai, M;Procopio, E;Mari, F;Sciruicchio, V;Conti, V;Fanelli, I;Bambi, F;Guerrini, R;Morrone, A;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of human induced pluripotent stem cell line MHHi029-A from a male Fabry disease patient carrying c.959A > T mutation
Authors: Jahn, C;Juchem, M;Sonnenschein, K;Gietz, A;Buchegger, T;Lachmann, N;Göhring, G;Behrens, YL;Bär, C;Thum, T;Hoepfner, J;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Distinct pathways drive anterior hypoblast specification in the implanting human embryo
Authors: Weatherbee, BAT;Weberling, A;Gantner, CW;Iwamoto-Stohl, LK;Barnikel, Z;Barrie, A;Campbell, A;Cunningham, P;Drezet, C;Efstathiou, P;Fishel, S;Vindel, SG;Lockwood, M;Oakley, R;Pretty, C;Chowdhury, N;Richardson, L;Mania, A;Weavers, L;Christie, L;Elder, K;Snell, P;Zernicka-Goetz, M;
Nature cell biology
Species: Human, Mouse
Sample Types: Embryo
Applications: Immunohistochemistry -
The shapes of elongating gastruloids are consistent with convergent extension driven by a combination of active cell crawling and differential adhesion
Authors: de Jong, MA;Adegeest, E;Bérenger-Currias, NMLP;Mircea, M;Merks, RMH;Semrau, S;
PLoS computational biology
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Generation of two hiPSCs lines of two patients carrying truncating mutations in the dimerization domain of filamin C
Authors: Daya, NM;Döring, K;Zhuge, H;Volke, L;Stab, V;Dietz, J;Athamneh, M;Roos, A;Zaehres, H;Güttsches, AK;Mavrommatis, L;Vorgerd, M;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Generation of the human induced pluripotent stem cell line (IBKMOLi003-A) from PBMCs of a vascular Ehlers-Danlos syndrome (vEDS) patient carrying the heterozygous nonsense mutation c.430C > T (p.Q105*) in the COL3A1 gene
Authors: Höpperger, S;Spathopoulou, A;Mayer-Suess, L;Suarez-Cubero, M;Sillaber, K;Spreiz, A;Kiechl, S;Edenhofer, F;Fellner, L;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Generation of induced pluripotent stem cell line from a patient suffering from arterial calcification due to deficiency of CD73 (ACDC)
Authors: Tripathi, D;Manhas, A;Noishiki, C;Wu, D;Adkar, S;Sallam, K;Fukaya, E;Leeper, NJ;Sayed, N;
Stem cell research
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of a human induced pluripotent stem cell line (SMUSHi002-A) from an ALS patient carrying a heterozygous mutation c.1562G > A in the FUS gene
Authors: Tang, M;Xiong, M;Zhou, W;Lei, J;Huang, M;Huang, C;Wang, F;Liu, J;Li, J;Xu, X;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: IHC/IF, Flow Cytometry -
Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson's disease
Authors: Park, S;Park, CW;Eom, JH;Jo, MY;Hur, HJ;Choi, SK;Lee, JS;Nam, ST;Jo, KS;Oh, YW;Lee, J;Kim, S;Kim, DH;Park, CY;Kim, SJ;Lee, HY;Cho, MS;Kim, DS;Kim, DW;
Cell stem cell
Species: Xenograft
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation
Authors: Melesio, J;Bonilauri, B;Li, A;Pang, PD;Liao, R;Witteles, RM;Wu, JC;Sallam, K;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of two induced pluripotent stem cell lines from a 33-year-old central core disease patient with a heterozygous dominant c.14145_14156delCTACTGGGACA (p.Asn4715_Asp4718del) deletion in the RYR1 gene
Authors: Driver, K;Vo, C;Scriba, CK;Saker, S;Larmonier, T;Malfatti, E;Romero, NB;Ravenscroft, G;Laing, NG;Taylor, RL;Clayton, JS;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation
Authors: Meyer, K;Lammers, NC;Bugaj, LJ;Garcia, HG;Weiner, OD;
Nature communications
Species: Mouse
Sample Types: Transfected Whole Cells, Whole Cells
Applications: ICC -
Generation of two human iPSC lines (HIMRi002-A and HIMRi003-A) derived from Caveolinopathy patients with rippling muscle disease
Authors: Boeing, A;Mavrommatis, L;Daya, NM;Zhuge, H;Volke, L;Kocabas, A;Kneifel, M;Athamneh, M;Krause, K;Südkamp, N;Döring, K;Theiss, C;Roos, A;Zaehres, H;Güttsches, AK;Vorgerd, M;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of novel human induced pluripotent stem cell (iPSC) lines originating from five asymptomatic individuals carrying the PLN-R14del pathogenic variant and a non-carrier relative
Authors: Balducci, V;Scardigli, F;Harakalova, M;Peter van Tintelen, J;Doevendans, PA;Costa, KD;Turnbull, IC;P G Sluijter, J;Stillitano, F;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell lines from Duchenne muscular dystrophy patients
Authors: Liu, W;Zeng, W;Kong, X;Htet, M;Yu, R;Wheeler, M;Day, JW;Wu, JC;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC, Flow Cytometry -
RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling
Authors: Militi, S;Nibhani, R;Jalali, M;Pauklin, S;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: ICC -
3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages
Authors: Karvas, RM;Zemke, JE;Ali, SS;Upton, E;Sane, E;Fischer, LA;Dong, C;Park, KM;Wang, F;Park, K;Hao, S;Chew, B;Meyer, B;Zhou, C;Dietmann, S;Theunissen, TW;
Cell stem cell
Species: Human
Sample Types: Protein
Applications: Immunocytochemistry -
Generation of an induced pluripotent stem cell line (NCHi010-A) from a 6-year-old female with Down syndrome and without congenital heart disease
Authors: Yu Y, Alonzo M, Ye S et al.
Stem Cell Research
-
Generation of iPSC line NCHi012-A from a patient with Alagille syndrome and heterozygous pathogenic variant in the JAG1 gene
Authors: Cunningham, D;Stanberry, I;Ye, S;Alonzo, M;Zhao, MT;Garg, V;Lilly, B;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of a human iPSC line (JUFMDOi007-A) from a patient with Usher syndrome due to mutation in USH2A
Authors: T Ukaji, M Takahashi-, D Arai, H Tsutsumi, S Tajima, W Akamatsu, F Matsumoto, K Ikeda, SI Usami, K Kamiya
Stem Cell Research, 2023-04-17;69(0):103100.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell lines from spinal muscular atrophy type 1 patients carrying no functional copies of SMN1 gene
Authors: W Zeng, X Kong, C Alamana, Y Liu, J Guzman, PD Pang, JW Day, JC Wu
Stem Cell Research, 2023-04-17;69(0):103095.
Species: Human
Sample Types: Transduced Whole Cells
Applications: ICC -
Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
Authors: JC Cossec, T Traboulsi, S Sart, Y Loe-Mie, M Guthmann, IA Hendriks, I Theurillat, ML Nielsen, ME Torres-Pad, CN Baroud, A Dejean
Cell Reports, 2023-04-15;42(4):112380.
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Generation of induced pluripotent stem cell line (UKWNLi008) derived from a patient carrying a c.1678C>G variant in the transient receptor potential cation channel subfamily A member (TRPA1) gene potentially associated with small fiber neuropathy
Authors: NM Schottmann, K Klug, E Klopocki, N Üçeyler
Stem Cell Research, 2023-04-12;69(0):103094.
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Cynomolgus monkey embryo model captures gastrulation and early pregnancy
Authors: J Li, Q Zhu, J Cao, Y Liu, Y Lu, Y Sun, Q Li, Y Huang, S Shang, X Bian, C Li, L Zhang, Y Wang, Y Nie, J Fu, W Li, MA Mazid, Y Jiang, W Jia, X Wang, Y Sun, MA Esteban, Q Sun, F Zhou, Z Liu
Cell Stem Cell, 2023-04-06;30(4):362-377.e7.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Embryo
Applications: Immunohistochemistry -
Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities
Authors: V Garg, Y Yang, S Nowotschin, M Setty, YY Kuo, R Sharma, A Polyzos, E Salataj, D Murphy, A Jang, D Pe'er, E Apostolou, AK Hadjantona
bioRxiv : the preprint server for biology, 2023-03-29;0(0):.
Species: Mouse
Sample Types: Cell Lysates, Whole Cells
Applications: ChIP, Flow Cytometry, ICC -
Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A
Authors: AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver
Stem Cell Research, 2023-03-26;69(0):103083.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Establishment of TUBB3-mCherry knock-in human pluripotent stem cell line using CRISPR/Cas9 (SNUe003-A-4)
Authors: AH Kim, HM Lee, HS Kim, J Jung, H Seol, E Choi, S Lee, Y Min Choi, JK Jun, HS Kim, J Jang
Stem Cell Research, 2023-03-08;69(0):103064.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023-03-02;30(3):264-282.e9.
Species: Human, Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: Flow Cytometry, ICC, IHC -
Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
Authors: P Madrigal, S Deng, Y Feng, S Militi, KJ Goh, R Nibhani, R Grandy, A Osnato, D Ortmann, S Brown, S Pauklin
Nature Communications, 2023-01-25;14(1):405.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell lines UKWNLi006 and UKWNLi007 derived from two patients with an active site GLA mutation leading to a pain and no pain phenotype in Fabry disease
Authors: K Klug, M Breyer, E Klopocki, N Üçeyler
Stem Cell Research, 2023-01-09;67(0):103025.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023;30(3):264-282.e9.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation
Authors: L Li, X Si, J Yang, M Lei, H Liu, J Ruan, H Fu, W Li, H Yang, X Lei, H Sang
Stem Cell Research, 2022-12-09;66(0):102995.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A reference human induced pluripotent stem cell line for large-scale collaborative studies
Authors: CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendra, L Peng, H Oguro, J Kanaujiya, J Zou, D Sebesta, G Pratt, E Cross, J Blockwick, P Buxton, L Kinner-Bib, C Medura, C Tompkins, S Hughes, M Santiana, F Faghri, MA Nalls, D Vitale, S Ballard, YA Qi, DM Ramos, KM Anderson, J Stadler, P Narayan, J Papademetr, L Reilly, MP Nelson, S Aggarwal, LU Rosen, P Kirwan, V Pisupati, SL Coon, SW Scholz, T Priebe, M Öttl, J Dong, M Meijer, LJM Janssen, VS Lourenco, R van der Ka, D Crusius, D Paquet, AC Raulin, G Bu, A Held, BJ Wainger, RMC Gabriele, JM Casey, S Wray, D Abu-Bonsra, CL Parish, MS Beccari, DW Cleveland, E Li, IVL Rose, M Kampmann, C Calatayud, P Verstreken, L Heinrich, MY Chen, B Schüle, D Dou, ELF Holzbaur, MC Zanellati, R Basundra, M Deshmukh, S Cohen, R Khanna, M Raman, ZS Nevin, M Matia, J Van Lent, V Timmerman, BR Conklin, K Johnson Ch, K Zhang, S Funes, DA Bosco, L Erlebach, M Welzer, D Kronenberg, G Lyu, E Arenas, E Coccia, L Sarrafha, T Ahfeldt, JC Marioni, WC Skarnes, MR Cookson, ME Ward, FT Merkle
Cell Stem Cell, 2022-12-01;29(12):1685-1702.e22.
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Generation of induced pluripotent stem cells from three individuals with Huntington's disease
Authors: DC Miller, P Lisowski, S Lickfett, B Mlody, M Bünning, C Genehr, C Ulrich, EE Wanker, S Diecke, J Priller, A Prigione
Stem Cell Research, 2022-11-17;65(0):102976.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension
Authors: M Bao, J Cornwall-S, E Sanchez-Va, DY Chen, J De Jonghe, S Shadkhoo, F Hollfelder, M Thomson, DM Glover, M Zernicka-G
Nature Cell Biology, 2022-09-13;24(9):1341-1349.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
LRP1 is a neuronal receptor for alpha-synuclein uptake and spread
Authors: K Chen, YA Martens, A Meneses, DH Ryu, W Lu, AC Raulin, F Li, J Zhao, Y Chen, Y Jin, C Linares, M Goodwin, Y Li, CC Liu, T Kanekiyo, DM Holtzman, TE Golde, G Bu, N Zhao
Molecular Neurodegeneration, 2022-09-02;17(1):57.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Spatial molecular anatomy of germ layers in the gastrulating cynomolgus monkey embryo
Authors: G Cui, S Feng, Y Yan, L Wang, X He, X Li, Y Duan, J Chen, K Tang, P Zheng, PPL Tam, W Si, N Jing, G Peng
Cell Reports, 2022-08-30;40(9):111285.
Species: Cynomolgus Monkey
Sample Types: Whole Cells
Applications: ICC/IF -
Generation of an induced pluripotent stem cell line NCHi003-A from a 11-year-old male with pulmonary atresia with intact ventricular septum (PA-IVS)
Authors: J Contreras, M Alonzo, S Ye, H Lin, L Hernandez-, KL McBride, K Texter, V Garg, MT Zhao
Stem Cell Research, 2022-08-10;64(0):102893.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS)
Authors: M Alonzo, J Contreras, S Ye, H Lin, L Hernandez-, KL McBride, K Texter, V Garg, MT Zhao
Stem Cell Research, 2022-08-09;64(0):102892.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Production of a human iPSC line from an early-onset Parkinson's disease patient with a novel CHCHD2 gene truncated mutation
Authors: Z Jiang, XJ Gu, WM Su, QQ Duan, JY Lin, B Cao, HF Shang, YP Chen
Stem Cell Research, 2022-08-04;64(0):102881.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing
Authors: J Liu, GC Black, SJ Kimber, PI Sergouniot
Stem Cell Research, 2022-07-30;64(0):102880.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
In�vitro atlas of dorsal spinal interneurons reveals Wnt signaling as a critical regulator of progenitor expansion
Authors: S Gupta, R Kawaguchi, E Heinrichs, S Gallardo, S Castellano, I Mandric, BG Novitch, SJ Butler
Oncogene, 2022-07-19;40(3):111119.
Species: Human
Sample Types: Embryoid Bodies
Applications: IHC -
Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1
Authors: YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen
Oncogene, 2022-06-14;63(0):102845.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A gastruloid model of the interaction between embryonic and extra-embryonic cell types
Authors: NM Bérenger-C, M Mircea, E Adegeest, PR van den Be, M Feliksik, M Hochane, T Idema, SJ Tans, S Semrau
Journal of tissue engineering, 2022-06-11;13(0):2041731422110.
Species: Mouse
Sample Types: Organoids
Applications: IHC -
In�vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells
Authors: M Simunovic, ED Siggia, AH Brivanlou
Cell Stem Cell, 2022-06-02;29(6):962-972.e4.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus
Authors: Y Shi, S Wu, B Yang, B Yu, Y Yan, J Yang, M Chu, X Hu
Stem Cell Research, 2022-05-04;62(0):102801.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of alphaMHC-EGFP knock-in in human pluripotent stem cell line, SNUe003-A-3 using CRISPR/Cas9-based gene targeting
Authors: HM Lee, AH Kim, S Hwang, J Jung, H Seol, JJ Sung, SM Jeong, YM Choi, JK Jun, HS Kim, J Jang
Stem Cell Research, 2022-04-04;61(0):102779.
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line FMUPDCi001-A from a patient with mental retardation, autosomal recessive 36 (MRT36) carrying the variants c.219dupA and c.587C�>�T in ADAT3
Authors: X Hu, S Xiong, X Zhou, L Sun
Stem Cell Research, 2022-04-04;61(0):102777.
Species: Human
Sample Types: Spheroid
Applications: ICC -
Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants
Authors: A Manhas, JWS Jahng, CD Vera, SP Shenoy, JW Knowles, JC Wu
Stem Cell Research, 2022-03-31;61(0):102774.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease
Authors: M Breyer, T Klein, K Klug, E Klopocki, N Üçeyler
Stem Cell Research, 2022-03-14;61(0):102747.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology
Authors: W Chiu, A Li, T Wang, W Li, X Zhang
Stem Cell Research, 2022-02-26;60(0):102729.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts
Authors: S Chumchuen, C Satirapod, A Tangprasit, S Hongeng
Stem Cell Research, 2022-01-19;60(0):102675.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of iPSC line (FAMRCi009-A) from patient with familial progressive cardiac conduction disorder carrying genetic variant FLNC p.Val2264Met
Authors: N Rodina, A Khudiakov, K Perepelina, A Muravyev, A Boytsov, A Zlotina, P Sokolnikov, A Kostareva
Stem Cell Research, 2021-12-27;59(0):102640.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL
Authors: G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker
Stem Cell Research, 2021-12-23;59(0):102635.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant
Authors: C Lee, S Cho, C Lai, S Shenoy, R Vagelos, JC Wu
Stem Cell Research, 2021-12-21;59(0):102638.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of iPSC line FAMRCi010-A from patient with restrictive cardiomyopathy carrying genetic variant FLNC p.Gly2011Arg
Authors: K Perepelina, A Khudiakov, N Rodina, A Boytsov, T Vavilova, A Zlotina, P Sokolnikov, A Kostareva
Stem Cell Research, 2021-12-21;59(0):102639.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations
Authors: N Belbachir, C Lai, JW Rhee, Y Zhuge, MV Perez, K Sallam, JC Wu
Stem Cell Research, 2021-11-23;57(0):102605.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
StemBond hydrogels control the mechanical microenvironment for pluripotent stem cells
Authors: C Labouesse, BX Tan, CC Agley, M Hofer, AK Winkel, GG Stirparo, HT Stuart, CM Verstreken, C Mulas, W Mansfield, P Bertone, K Franze, JCR Silva, KJ Chalut
Nature Communications, 2021-10-21;12(1):6132.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Comparison of Differentiation Pattern and WNT/SHH Signaling in Pluripotent Stem Cells Cultured under Different Conditions
Authors: B ?wierczek-, D Dudka, D Bauer, T Czajkowski, K Ilach, W Streminska, A Kominek, K Piwocka, MA Ciemerych, K Archacka
Cells, 2021-10-14;10(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Immunolocalization -
Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing
Authors: L Scaramuzzi, V Lucchino, S Scalise, M Lo Conte, C Zannino, A Sacco, F Biamonte, EI Parrotta, FS Costanzo, G Cuda
Cells, 2021-09-15;10(9):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Rapid target validation in a Cas9-inducible hiPSC derived kidney model
Authors: Y Shamshirga, A Jonebring, A Svensson, I Leefa, M Bohlooly-Y, M Firth, KJ Woollard, A Hofherr, IM Rogers, R Hicks
Scientific Reports, 2021-08-16;11(1):16532.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells
Authors: BC Liu, FY Liu, XY Gao, YL Chen, QQ Meng, YL Song, XH Li, SQ Bao
International Journal of Molecular Sciences, 2021-07-12;22(14):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Dynamics of primitive streak regression controls the fate of neuromesodermal progenitors in the chicken embryo
Authors: C Guillot, Y Djeffal, A Michaut, B Rabe, O Pourquié
Elife, 2021-07-06;10(0):.
Species: Chicken
Sample Types: Embryo
Applications: IHC -
Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity
Authors: G Iannello, A Patel, D Sirabella, B Corneo, V Thaker
Stem Cell Research, 2021-06-21;54(0):102432.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
Authors: L Ma, M Schmidt, EM Morrow
Stem Cell Research, 2021-06-18;54(0):102435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1
Authors: PS Huang, MH Wen, X Xie, A Xu, DF Lee, TY Chen
Stem Cell Research, 2021-06-06;54(0):102415.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of an arrhythmogenic right ventricular cardiomyopathy derived iPSC cell line (USFi004-A) carrying a heterozygous mutation in PKP2 (c.1799delA)
Authors: J Yang, E Samal, M Burgos Ang, A Bertalovit, TV McDonald
Stem Cell Research, 2021-05-19;54(0):102398.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an iPSC cell line (USFi003-A) from a patient with dilated cardiomyopathy carrying a heterozygous mutation in LMNA (p.R541C)
Authors: J Yang, M Burgos Ang, MA Argenziano, A Bertalovit, M Najari Bei, TV McDonald
Stem Cell Research, 2021-05-13;54(0):102396.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a heterozygous FLNC mutation-carrying human iPSC line, USFi002-A, for modeling dilated cardiomyopathy
Authors: MA Argenziano, M Burgos Ang, M Najari Bei, J Yang, AC Bertalovit, TV McDonald
Stem Cell Research, 2021-05-12;53(0):102394.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cells from subjects with Lesch-Nyhan disease
Authors: DJ Sutcliffe, AR Dinasarapu, JE Visser, JD Hoed, F Seifar, P Joshi, I Ceballos-P, T Sardar, EJ Hess, YV Sun, Z Wen, ME Zwick, HA Jinnah
Scientific Reports, 2021-04-19;11(1):8523.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of human induced pluripotent stem cell lines (UNIMGi003-A and UNIMGi004-A) from two Italian siblings affected by Unverricht-Lundborg disease
Authors: V Lucchino, L Scaramuzzi, S Scalise, K Grillone, M Lo Conte, C Esposito, U Aguglia, E Ferlazzo, N Perrotti, P Malatesta, EI Parrotta, G Cuda
Stem Cell Research, 2021-04-09;53(0):102329.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of pathogenic TPP1 mutations in human stem cells as a model for neuronal ceroid lipofuscinosis type 2 disease
Authors: L Ma, AM Prada, M Schmidt, EM Morrow
Stem Cell Research, 2021-04-06;53(0):102323.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder
Authors: LG Devito, L Healy, S Mohammed, F Guillemot, C Dias
Stem Cell Research, 2021-03-20;53(0):102304.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene
Authors: JWS Jahng, KE Black, L Liu, HR Bae, M Perez, EA Ashley, K Sallam, JC Wu
Stem Cell Research, 2021-03-12;53(0):102284.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy
Authors: L Liu, SP Shenoy, JWS Jahng, Y Liu, JW Knowles, Y Zhuge, JC Wu
Stem Cell Research, 2021-03-11;53(0):102279.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (?2/?3/?4) and knock-out for the study of APOE biology in health and disease
Authors: B Schmid, B Holst, C Clausen, L Bahnassawy, P Reinhardt, MHM Bakker, E Díaz-Guerr, C Vicario, PV Martino-Ad, M Thoenes, A Ramirez, K Flissbach, C Grezella, O Brüstle, M Peitz, A Ebneth, A Cabrera-So
Stem Cell Research, 2021-02-02;52(0):102180.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
Authors: M Kinoshita, M Barber, W Mansfield, Y Cui, D Spindlow, GG Stirparo, S Dietmann, J Nichols, A Smith
Cell Stem Cell, 2020-12-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of iPSC lines from two patients affected by febrile seizure due to inherited missense mutation in SCN1A gene
Authors: S Scalise, L Scaramuzzi, V Lucchino, C Esposito, P Malatesta, K Grillone, N Perrotti, G Cuda, EI Parrotta
Stem Cell Research, 2020-11-07;49(0):102083.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
Authors: FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, C Villacorta, A Berical, JC Jean, J Le Suer, T Matte, C Simone-Roa, Y Tang, TM Schlaeger, AM Crane, N Matthias, SXL Huang, SH Randell, J Wu, JR Spence, G Carraro, BR Stripp, A Rab, EJ Sorsher, A Horani, SL Brody, BR Davis, DN Kotton
Cell Stem Cell, 2020-10-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Molecular Analysis of Fetal and Adult Primary Human Liver Sinusoidal Endothelial Cells: A Comparison to Other Endothelial Cells
Authors: MA Jamil, H Singer, R Al-Rifai, N Nüsgen, M Rath, S Strauss, I Andreou, J Oldenburg, O El-Maarri
Int J Mol Sci, 2020-10-21;21(20):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome
Authors: SR Sripathy, Y Wang, RL Moses, A Fatemi, DA Batista, BJ Maher
Stem Cell Res, 2020-09-17;48(0):102001.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson�s disease patient carrying the heterozygous p.A30P mutation in SNCA
Authors: PA Barbuti, BFR Santos, CM Dording, G Cruciani, F Massart, A Hummel, R Krüger
Stem Cell Res, 2020-08-08;48(0):101951.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two iPSC lines (FAMRCi007-A and FAMRCi007-B) from patient with Emery-Dreifuss muscular dystrophy and heart rhythm abnormalities carrying genetic variant LMNA p.Arg249Gln
Authors: K Perepelina, A Kostina, P Klauzen, A Khudiakov, M Rabino, S Crasto, A Zlotina, Y Fomicheva, A Sergushich, M Oganesian, A Dmitriev, A Kostareva, E Di Pasqual, A Malashiche
Stem Cell Res, 2020-06-29;47(0):101895.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation and characterization of four Chediak-Higashi Syndrome (CHS) induced pluripotent stem cell (iPSC) lines
Authors: J Serra-Vina, MB Sandler, E Pak, W Zheng, A Dutra, W Introne, WA Gahl, MC Malicdan
Stem Cell Res, 2020-06-22;47(0):101883.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Crisponi syndrome/cold-induced sweating syndrome type 2: Reprogramming of CS/CISS2 individual derived fibroblasts into three clones of one iPSC line
Authors: I Buers, L Schöning, N Tomas Loge, Y Nitschke, IM Höben, A Röpke, L Crisponi, H Omran, F Rutsch
Stem Cell Res, 2020-06-01;46(0):101855.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of induced pluripotent stem cell lines from a Crisponi/Cold induced sweating syndrome type 1 individual
Authors: L Schöning, NT Loges, Y Nitschke, IM Höben, A Röpke, L Crisponi, H Omran, F Rutsch, I Buers
Stem Cell Res, 2020-05-28;46(0):101820.
Species: Human
Sample Types: Whole Cell
Applications: Flow Cytometry, ICC -
GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
Authors: A Gunne-Brad, A Sullivan, B Gharibi, RSM Sheriff, A Maity, YF Wang, A Edwards, M Jiang, M Howell, R Goldstone, R Wollman, P East, SDM Santos
Cell Stem Cell, 2020-04-16;26(5):693-706.e9.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Gut Microbiota Modulate CD8�T Cell Responses to Influence Colitis-Associated Tumorigenesis
Authors: AI Yu, L Zhao, KA Eaton, S Ho, J Chen, S Poe, J Becker, A Gonzalez, D McKinstry, M Hasso, J Mendoza-Ca, J Whitfield, C Koumpouras, PD Schloss, EC Martens, GY Chen
Cell Rep, 2020-04-07;31(1):107471.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation
Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
Stem Cell Res, 2020-03-29;45(0):101781.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell lines (FAMRCi005-A and FAMRCi005-B) from patient carrying genetic variant LMNA p.Asp357Val
Authors: P Klauzen, K Perepelina, A Khudiakov, A Zlotina, Y Fomicheva, T Pervunina, T Vershinina, A Kostareva, A Malashiche
Stem Cell Res, 2020-02-05;43(0):101719.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two iPSC lines (FAMRCi004-A and FAMRCi004-B) from patient with familial progressive cardiac conduction disorder carrying genetic variant DSP p.His1684Arg
Authors: A Khudiakov, K Perepelina, P Klauzen, A Zlotina, K Gusev, E Kaznacheye, A Malashiche, A Kostareva
Stem Cell Res, 2020-02-04;43(0):101720.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, IF/ICC -
Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro
Authors: K Perepelina, P Klauzen, A Khudiakov, A Zlotina, Y Fomicheva, D Rudenko, M Gordeev, A Sergushich, A Malashiche, A Kostareva
Stem Cell Res, 2020-01-31;43(0):101714.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Chromosome Transplantation: A Possible Approach to Treat Human X-linked Disorders
Authors: M Paulis, L Susani, A Castelli, T Suzuki, T Hara, L Straniero, S Duga, D Strina, S Mantero, E Caldana, LS Sergi, A Villa, P Vezzoni
Mol Ther Methods Clin Dev, 2020-01-21;17(0):369-377.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In Vitro Fabrication of Hybrid Bone/Cartilage Complex Using Mouse Induced Pluripotent Stem Cells
Authors: P Limraksasi, T Kondo, M Zhang, H Okawa, T Osathanon, P Pavasant, H Egusa
Int J Mol Sci, 2020-01-16;21(2):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual
Authors: NV Fuchs, M Schieck, M Neuenkirch, C Tondera, H Schmitz, D Steinemann, G Göhring, R König
Stem Cell Res, 2019-12-04;42(0):101679.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings
Authors: Y Hu, CM Domínguez, J Bauer, S Weigel, A Schipperge, C Oelschlaeg, N Willenbach, S Keppler, M Bastmeyer, S Hei beta ler, C Wöll, T Scharnwebe, KS Rabe, CM Niemeyer
Nat Commun, 2019-12-04;10(1):5522.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells
Authors: P Wörsdörfer, N Dalda, A Kern, S Krüger, N Wagner, CK Kwok, E Henke, S Ergün
Sci Rep, 2019-10-30;9(1):15663.
Species: Human
Sample Types: Cell Lysates, Whole Tissue
Applications: IHC-P, Western Blot -
Induced pluripotent stem cell line (INSAi001-A) from a Gaucher disease type 3 patient compound heterozygote for mutations in the GBA1 gene
Authors: AJ Duarte, D Ribeiro, R Santos, L Moreira, J Bragança, O Amaral
Stem Cell Res, 2019-10-18;41(0):101595.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
Authors: S Chhabra, L Liu, R Goh, X Kong, A Warmflash
PLoS Biol., 2019-10-15;17(10):e3000498.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A)
Authors: NV Fuchs, M Schieck, M Neuenkirch, C Tondera, H Schmitz, V des Portes, D Germanaud, D Steinemann, G Göhring, R König
Stem Cell Res, 2019-10-15;41(0):101592.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus
Authors: MT De Angelis, G Santamaria, EI Parrotta, S Scalise, M Lo Conte, S Gasparini, E Ferlazzo, U Aguglia, C Ciampi, A Sgura, G Cuda
J. Cell. Mol. Med., 2019-09-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (FRIMOi007-A) derived from an incomplete achromatopsia patient carrying a novel homozygous mutation in PDE6C gene
Authors: J Domingo-Pr, V Abad-Moral, M Riera, R Navarro, B Corcostegu, E Pomares
Stem Cell Res, 2019-09-04;40(0):101569.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of Best disease-derived induced pluripotent stem cell line (FRIMOi006-A) carrying a novel dominant mutation in BEST1 gene
Authors: J Domingo-Pr, M Riera, V Abad-Moral, S Ruiz-Nogal, B Corcostegu, E Pomares
Stem Cell Res, 2019-09-04;40(0):101570.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of PITX3-mCherry knock-in reporter human embryonic stem cell line (WAe009-A-23)
Authors: S Park, JE Yoo, DR Lee, J Jang, MS Cho, DS Kim, DW Kim
Stem Cell Res, 2019-07-18;39(0):101499.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Authors: M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizad, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespad, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss
Cell Stem Cell, 2019-06-13;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Establishment of an induced pluripotent stem cell line (FRIMOi005-A) derived from a retinitis pigmentosa patient carrying a dominant mutation in RHO gene
Authors: J Domingo-Pr, M Riera, A Burés-Jels, B Corcostegu, E Pomares
Stem Cell Res, 2019-05-22;38(0):101468.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency
Authors: T Kalkan, S Bornelöv, C Mulas, E Diamanti, T Lohoff, M Ralser, S Middelkamp, P Lombard, J Nichols, A Smith
Cell Stem Cell, 2019-04-25;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
User-defined morphogen patterning for directing human cell fate stratification
Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
Sci Rep, 2019-04-23;9(1):6433.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells
Authors: Garreta E, Prado P, Tarantino C et al.
Nature Materials
-
Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells
Authors: X Wei, J Guo, Q Li, Q Jia, Q Jing, Y Li, B Zhou, J Chen, S Gao, X Zhang, M Jia, C Niu, W Yang, X Zhi, X Wang, D Yu, L Bai, L Wang, J Na, Y Zou, J Zhang, S Zhang, D Meng
Sci Adv, 2019-03-13;5(3):eaau7887.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Generation of two iPS cell lines (FRIMOi003-A and FRIMOi004-A) derived from Stargardt patients carrying ABCA4 compound heterozygous mutations
Authors: M Riera, A Patel, A Burés-Jels, B Corcostegu, S Chang, E Pomares, B Corneo, JR Sparrow
Stem Cell Res, 2019-02-13;36(0):101389.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations
Authors: M Riera, A Patel, B Corcostegu, S Chang, JR Sparrow, E Pomares, B Corneo
Stem Cell Res, 2019-01-17;35(0):101385.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (FRIMOi002-A) from a retinitis pigmentosa patient carrying compound heterozygous mutations in USH2A gene
Authors: M Riera, A Patel, B Corcostegu, S Chang, B Corneo, JR Sparrow, E Pomares
Stem Cell Res, 2019-01-17;35(0):101386.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
Stem Cell Res, 2018-12-10;34(0):101361.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Lineage-Specific Chiral Biases of Human Embryonic Stem Cells during Differentiation
Authors: KE Worley, AS Chin, LQ Wan
Stem Cells Int, 2018-12-02;2018(0):1848605.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143.
Authors: Baulier E, Garcia Diaz A, Corneo B, Farber D
Stem Cell Res, 2018-11-28;33(0):274-277.
-
Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
Authors: X Gao, JJ Yourick, RL Sprando
Stem Cell Res, 2018-07-27;31(0):193-196.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
Authors: AL Gagne, JA Maguire, S Gandre-Bab, ST Chou, SK Tasian, ML Loh, MJ Weiss, P Gadue, DL French
Stem Cell Res, 2018-07-05;31(0):157-160.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In vitro generation of mouse polarized embryo-like structures from embryonic and trophoblast stem cells
Authors: SE Harrison, B Sozen, M Zernicka-G
Nat Protoc, 2018-07-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
The non-canonical Wnt-PCP pathway shapes the caudal neural plate
Authors: B López-Esco, JM Caro-Vega, DS Vijayragha, TF Plageman, JA Sanchez-Al, RC Moreno, D Savery, J Márquez-Ri, LA Davidson, P Ybot-Gonzá
Development, 2018-05-08;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks
Authors: N Briand, AC Guénantin, D Jeziorowsk, A Shah, M Mantecon, E Capel, M Garcia, A Oldenburg, J Paulsen, JS Hulot, C Vigouroux, P Collas
Hum. Mol. Genet., 2018-04-15;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
Cell Stem Cell, 2018-04-05;22(4):543-558.e12.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling
Authors: S Schmidt, N Schumacher, J Schwarz, S Tangermann, L Kenner, M Schlederer, M Sibilia, M Linder, A Altendorf-, T Knösel, ES Gruber, G Oberhuber, J Bolik, A Rehman, A Sinha, J Lokau, P Arnold, AS Cabron, F Zunke, C Becker-Pau, A Preaudet, P Nguyen, J Huynh, S Afshar-Ste, AL Chand, J Westermann, PJ Dempsey, C Garbers, D Schmidt-Ar, P Rosenstiel, T Putoczki, M Ernst, S Rose-John
J. Exp. Med., 2018-02-22;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
Mol. Syst. Biol., 2018-01-29;14(1):e7952.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells
Authors: MT De Angelis, EI Parrotta, G Santamaria, G Cuda
Cell Death Dis, 2018-01-05;9(1):6.
Species: Human
Sample Types: Embryoid Bodies
Applications: ICC -
Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75year old female
Authors: S Martins, M Bohndorf, F Schröter, F Assar, W Wruck, K Sleegers, C Van Broeck, J Adjaye
Stem Cell Res, 2017-12-13;26(0):76-79.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency
Authors: CY Yu, TC Li, YY Wu, CH Yeh, W Chiang, CY Chuang, HC Kuo
Nat Commun, 2017-10-27;8(1):1149.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
Sci Rep, 2017-08-17;7(1):8491.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells
Authors: KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima
Stem Cell Reports, 2017-06-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Guided self-organization and cortical plate formation in human brain organoids
Authors: MA Lancaster, NS Corsini, S Wolfinger, EH Gustafson, AW Phillips, TR Burkard, T Otani, FJ Livesey, JA Knoblich
Nat. Biotechnol., 2017-05-31;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos
Authors: M Oginuma, P Moncuquet, F Xiong, E Karoly, J Chal, K Guevorkian, O Pourquié
Dev. Cell, 2017-02-27;40(4):342-353.e10.
Species: Chicken
Sample Types: Whole Tissue
Applications: IHC -
The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells
Authors: Joan Massagué
Cell Stem Cell, 2016-11-23;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Real-time and Non-invasive Monitoring of Embryonic Stem Cell Survival during the Development of Embryoid Bodies with Smart Nanosensor
Authors: Dong-An Wang
Acta Biomater, 2016-11-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Jak1/Stat3 signaling acts as a positive regulator of pluripotency in chicken pre-gastrula embryos
Authors: Kiyokazu Agata
Dev. Biol., 2016-11-03;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells
PLoS ONE, 2016-11-01;11(11):e0165715.
Species: Human
Sample Types: Whole Cells
Applications: IHC-P -
ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation
Stem Cell Res, 2016-08-04;17(2):222-227.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells
PLoS ONE, 2016-07-13;11(7):e0159246.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Response to Extrinsic Bone Morphogenetic Protein (BMP) Signaling
Authors: L Song, J Chen, G Peng, K Tang, N Jing
J. Biol. Chem., 2016-05-16;291(29):15212-25.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
Authors: Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, Cui W
Nat Commun, 2015-05-22;6(0):7212.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: IHC, Western Blot -
An alternative pluripotent state confers interspecies chimaeric competency.
Authors: Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause M, Nery J, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim N, Lajara J, Guillen P, Campistol J, Esteban C, Ross P, Saghatelian A, Ren B, Ecker J, Izpisua Belmonte J
Nature, 2015-05-06;521(7552):316-21.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: IHC -
Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation.
Authors: Garriock R, Chalamalasetty R, Kennedy M, Canizales L, Lewandoski M, Yamaguchi T
Development, 2015-05-01;142(9):1628-38.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
Authors: Maury Y, Come J, Piskorowski R, Salah-Mohellibi N, Chevaleyre V, Peschanski M, Martinat C, Nedelec S
Nat Biotechnol, 2014-11-10;33(1):89-96.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
PLoS Biol, 2014-08-26;12(8):e1001937.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
SRF is essential for mesodermal cell migration during elongation of the embryonic body axis.
Authors: Schwartz B, Marks M, Wittler L, Werber M, Wahrisch S, Nordheim A, Herrmann B, Grote P
Mech Dev, 2014-07-11;133(0):23-35.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
T-box transcription factor brachyury is associated with prostate cancer progression and aggressiveness.
Authors: Pinto F, Pertega-Gomes N, Pereira M, Vizcaino J, Monteiro P, Henrique R, Baltazar F, Andrade R, Reis R
Clin Cancer Res, 2014-07-09;20(18):4949-61.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8.
Authors: Abe T, Shin J, Hosur K, Udey M, Chavakis T, Hajishengallis G
J Immunol, 2014-06-23;193(3):1383-91.
Species: Mouse
Sample Types: Whole Organism
Applications: In Vivo -
Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm.
Authors: Engels M, Rajarajan K, Feistritzer R, Sharma A, Nielsen U, Schalij M, de Vries A, Pijnappels D, Wu S
Stem Cells, 2014-06-01;32(6):1493-502.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm.
Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
Nat Commun, 2014-04-24;5(0):3678.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.
Authors: Tsakiridis, Anestis, Huang, Yali, Blin, Guillaum, Skylaki, Stavroul, Wymeersch, Filip, Osorno, Rodrigo, Economou, Costas, Karagianni, Eleni, Zhao, Suling, Lowell, Sally, Wilson, Valerie
Development, 2014-03-01;141(6):1209-21.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function.
Authors: Fang F, Wasserman S, Torres-Vazquez J, Weinstein B, Cao F, Li Z, Wilson K, Yue W, Wu J, Xie X, Pei X
J Cell Sci, 2014-01-24;127(0):1428-40.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Oct4 is required ~E7.5 for proliferation in the primitive streak.
Authors: DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra P, Nagy A, van der Kooy D
PLoS Genet, 2013-11-14;9(11):e1003957.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation.
Authors: Comes, Stefania, Gagliardi, Miriam, Laprano, Nicola, Fico, Annalisa, Cimmino, Amelia, Palamidessi, Andrea, De Cesare, Dario, De Falco, Sandro, Angelini, Claudia, Scita, Giorgio, Patriarca, Eduardo, Matarazzo, Maria R, Minchiotti, Gabriell
Stem Cell Reports, 2013-10-10;1(4):307-21.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells.
Authors: Evans AL, Faial T, Gilchrist MJ
PLoS ONE, 2012-03-30;7(3):e33346.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
Stem Cells Dev, 2012-02-21;21(12):2312-21.
Species: Human
Sample Types: Whole Cells
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A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
Authors: Bone HK, Nelson AS, Goldring CE, Tosh D, Welham MJ
J. Cell. Sci., 2011-05-24;124(0):1992-2000.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.
Authors: Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P
Dev. Biol., 2009-04-07;330(2):286-304.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells.
Authors: Vijayaragavan K, Szabo E, Bosse M, Ramos-Mejia V, Moon RT, Bhatia M
Cell Stem Cell, 2009-03-06;4(3):248-62.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
Authors: Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL
Nat. Cell Biol., 2008-06-22;10(7):837-48.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
Blood, 2007-11-27;111(4):1933-41.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Creation of engineered human embryonic stem cell lines using phiC31 integrase.
Authors: Thyagarajan B, Liu Y, Shin S, Lakshmipathy U, Scheyhing K, Xue H, Ellerstrom C, Strehl R, Hyllner J, Rao MS, Chesnut JD
Stem Cells, 2007-10-25;26(1):119-26.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking.
Authors: De Bank PA, Hou Q, Warner RM, Wood IV, Ali BE, Macneil S, Kendall DA, Kellam B, Shakesheff KM, Buttery LD
Biotechnol. Bioeng., 2007-08-15;97(6):1617-25.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
A porous photocurable elastomer for cell encapsulation and culture.
Authors: Gerecht S, Townsend SA, Pressler H, Zhu H, Nijst CL, Bruggeman JP, Nichol JW, Langer R
Biomaterials, 2007-08-09;28(32):4826-35.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
Authors: McLean AB, D'Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S
Stem Cells, 2007-01-01;25(1):29-38.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
FEBS Lett., 2006-10-02;580(25):5869-74.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
Proc. Natl. Acad. Sci. U.S.A., 2006-04-21;103(18):6907-12.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.
Authors: Bertero A, Fields P A et al.
J Cell Biol
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Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Authors: Gianluca Amadei, Kasey Y.C. Lau, Joachim De Jonghe, Carlos W. Gantner, Berna Sozen, Christopher Chan et al.
Developmental Cell
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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning
Authors: Sophie M Morgani, Jakob J Metzger, Jennifer Nichols, Eric D Siggia, Anna-Katerina Hadjantonakis
eLife
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Endothelial Differentiation of CCM1 Knockout iPSCs Triggers the Establishment of a Specific Gene Expression Signature
Authors: Robin A. Pilz, Dariush Skowronek, Lara Mellinger, Sander Bekeschus, Ute Felbor, Matthias Rath
International Journal of Molecular Sciences
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SMAD4 Is Essential for Human Cardiac Mesodermal Precursor Cell Formation
Authors: Jiejia Xu, Peter J. Gruber, Kenneth R. Chien
Stem Cells
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Mesendogen, a novel inhibitor of TRPM6, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells through alteration of magnesium homeostasis
Authors: Yijie Geng, Bradley Feng
Heliyon
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Establishment of NCHi009-A, an iPSC line from a patient with hypoplastic left heart syndrome (HLHS) carrying a heterozygous NOTCH1 mutation
Authors: S Adhicary, S Ye, H Lin, K Texter, V Garg, MT Zhao
Stem Cell Research, 2022-12-31;66(0):103013.
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A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse
Authors: Claire S. Simon, Lu Zhang, Tao Wu, Weibin Cai, Nestor Saiz, Sonja Nowotschin et al.
Biology Open
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Generation of three induced pluripotent stem cell lines to model and investigate diseases affecting Hispanics
Authors: Ian Y. Chen, Joseph Olshausen, Dilip Thomas, Celine Lai, Tracey L. McLaughlin, Joseph C. Wu
Stem Cell Research
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beta-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
Authors: LeBlanc L, Kim M, Kambhampati A Et al.
iScience
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Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
Authors: Jonathon M. Muncie, Nadia M.E. Ayad, Johnathon N. Lakins, Xufeng Xue, Jianping Fu, Valerie M. Weaver
Developmental Cell
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A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice
Authors: Laina Freyer, Christian Schröter, Néstor Saiz, Nadine Schrode, Sonja Nowotschin, Alfonso Martinez-Arias et al.
BMC Developmental Biology
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Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors
Authors: Ortwin Naujok, Jana Lentes, Ulf Diekmann, Claudia Davenport, Sigurd Lenzen
BMC Research Notes
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Generation of bicistronic reporter knockin mice for visualizing germ layers
Authors: Hayate Suzuki, Tra Thi Huong Dinh, Yoko Daitoku, Yoko Tanimoto, Kanako Kato, Takuya Azami et al.
Experimental Animals
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Asymmetry in the frequency and position of mitosis in the mouse embryo epiblast at gastrulation
Authors: Navrita Mathiah, Evangéline Despin‐Guitard, Matthew Stower, Wallis Nahaboo, Sema Elif Eski, Sumeet Pal Singh et al.
EMBO reports
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Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling
Authors: Xin Huang, Sophie Balmer, Fan Yang, Miguel Fidalgo, Dan Li, Diana Guallar et al.
eLife
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High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
Authors: KT Minn, YC Fu, S He, S Dietmann, SC George, MA Anastasio, SA Morris, L Solnica-Kr
Elife, 2020-11-18;9(0):.
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SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)
Authors: Kohei Yamamizu, David Schlessinger, Minoru S. H. Ko
Development
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Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells
Authors: Laura Prochazka, Yale S Michaels, Charles Lau, Ross D Jones, Mona Siu, Ting Yin et al.
Molecular Systems Biology
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Accelerated differentiation of human pluripotent stem cells into neural lineages via an early intermediate ectoderm population
Authors: Patrick Walsh, Vincent Truong, Sushmita Nayak, Marietta Saldías Montivero, Walter C. Low, Ann M. Parr et al.
Stem Cells
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Targeting the Cohesive Cluster Phenotype in Chordoma via beta 1 Integrin Increases Ionizing Radiation Efficacy12
Authors: William L. Harryman, Jaime M.C. Gard, Kelvin W. Pond, Skyler J. Simpson, Lucas H. Heppner, Daniel Hernandez-Cortes et al.
Neoplasia
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Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
Authors: Michèle Romanos, Guillaume Allio, Myriam Roussigné, Léa Combres, Nathalie Escalas, Cathy Soula et al.
eLife
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Generation and characterization of a human induced pluripotent stem cell (iPSC) line from a patient with congenital heart disease (CHD)
Authors: H Lin, SQ Ye, ZH Xu, JS Penaloza, M Aljuhani, T Vetter, MT Zhao, KL McBride
Stem Cell Research, 2022-10-31;65(0):102958.
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Excitable Dynamics and Yap-Dependent Mechanical Cues Drive the Segmentation Clock
Authors: Alexis Hubaud, Ido Regev, L. Mahadevan, Olivier Pourquié
Cell
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Directed Endothelial Progenitor Differentiation from Human Pluripotent Stem Cells Via Wnt Activation Under Defined Conditions
Authors: Xiaoping Bao, Xiaojun Lian, Sean P. Palecek
Methods in Molecular Biology
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WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
Elife, 2018-10-12;7(0):.
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Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
Authors: Q Li, Q Huang
PLoS ONE, 2019-10-10;14(10):e0223724.
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Lineage tracing of axial progenitors using Nkx1-2CreERT2 mice defines their trunk and tail contributions
Authors: Aida Rodrigo Rodrigo Albors, Pamela A. Halley, Kate G. Storey
Development
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Tnfaip2/exoc3 ‐driven lipid metabolism is essential for stem cell differentiation and organ homeostasis
Authors: Sarmistha Deb, Daniel A Felix, Philipp Koch, Maharshi Krishna Deb, Karol Szafranski, Katrin Buder et al.
EMBO reports
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Generation of two human iPSC lines with Exon 3 mutations in BCL2-Associated Athanogene 3 (BAG3) from dilated cardiomyopathy patients
Authors: PH Zushin, Y Zhou, A Li, EA Ashley, MT Wheeler, JC Wu
Stem Cell Research, 2023-01-05;67(0):103019.
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Epiblast-like stem cells established by Wnt/ beta -catenin signaling manifest distinct features of formative pluripotency and germline competence
Authors: Qing Luo, Han-pin Pui, Jiayu Chen, Leqian Yu, Paulo R. Jannig, Yu Pei et al.
Cell Reports
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Emergence and patterning dynamics of mouse-definitive endoderm
Authors: Maayan Pour, Abhishek Sampath Kumar, Naama Farag, Adriano Bolondi, Helene Kretzmer, Maria Walther et al.
iScience
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SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate
Authors: Naoko Irie, Leehee Weinberger, Walfred W.C. Tang, Toshihiro Kobayashi, Sergey Viukov, Yair S. Manor et al.
Cell
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Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
Authors: Wai Hoe Ng, Elizabeth K Johnston, Jun Jie Tan, Jacqueline M Bliley, Adam W Feinberg, Donna B Stolz et al.
eLife
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Diverse Routes toward Early Somites in the Mouse Embryo
Authors: Carolina Guibentif, Jonathan A. Griffiths, Ivan Imaz-Rosshandler, Shila Ghazanfar, Jennifer Nichols, Valerie Wilson et al.
Developmental Cell
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A dorsal-ventral gradient of Wnt3a/ beta -catenin signals controls mouse hindgut extension and colon formation
Authors: Robert J. Garriock, Ravindra B. Chalamalasetty, JianJian Zhu, Mark W. Kennedy, Amit Kumar, Susan Mackem et al.
Development
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BRACHYURY directs histone acetylation to target loci during mesoderm development
Authors: Arica Beisaw, Pavel Tsaytler, Frederic Koch, Sandra U Schmitz, Maria‐Theodora Melissari, Anna D Senft et al.
EMBO reports
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Immunohistochemistry on fixed 2D cell culture.
Primary antibody was used at 5ug/mL and incubated overnight. Brachyury-positive cells are visualized in red, nuclei are counterstained by Dapi (blue).