Human/Mouse HIF-1 alpha/HIF1A Alexa Fluor® 647-conjugated Antibody
Human/Mouse HIF-1 alpha/HIF1A Alexa Fluor® 647-conjugated Antibody Summary
Arg575-Asn826
Accession # Q16665.1
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: HIF-1 alpha/HIF1A
The hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha ) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the broad impact of gene regulation by HIF-1 alpha.
Product Datasheets
Product Specific Notices
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
Citation for Human/Mouse HIF-1 alpha/HIF1A Alexa Fluor® 647-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasis
Authors: WB Wang, YD Lin, L Zhao, C Liao, Y Zhang, M Davila, J Sun, Y Chen, N Xiong
Nature Immunology, 2023-01-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
FAQs
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This HIF1a antibody does not work. There is no difference between our HIF1a KO cells nor between 20% and 1%. We have validated our KO cells through Sanger sequencing as well as we have used an antibody from a different company and that did show proper KO staining. I am hoping my lab can get a refund for this antibody as we wasted a lot of time and resources using it.
