Human/Mouse Kirrel2/NEPH3 Antibody

Catalog #: MAB2564
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB2564
MAB2564-SP

Product Details

Citations (2)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse Kirrel2/NEPH3 Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse Kirrel2/NEPH3 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG₁ Clone # 318311

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Kirrel2
Gly21-Arg503
Accession # Q6UWL6

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Kirrel2 (Catalog # 2564-K2)
Recombinant Mouse Kirrel2 (Catalog # 2930-K2)
under non-reducing conditions only

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Kirrel2/NEPH3

Kirrel2, also known as nephrin-like 3, nephrin-like gene 1 and filtrin, is a type I transmembrane protein belonging to the immunoglobulin superfamily. By alternative splicing, at least 5 isoforms that differ in their extracellular and/or intracellular regions have been described. Kirrel2 is expressed in the pancreas, lymph nodes, kidney glomerulus, as well as brain. The extracellular domains of human and mouse Kirrel2 share 86% amino acid sequence identity.

Long Name

Kin of Irregular Chiasm-like 2, Splice Variant A

Entrez Gene IDs

84063 (Human); 243911 (Mouse)

Alternate Names

DKFZp564A1164; Filtrin; FILTRINkin of IRRE-like protein 2; kin of IRRE like 2 (Drosophila); Kin of irregular chiasm-like protein 2; Kirrel2; MGC15718; NEPH3; NEPH3Nephrin-like protein 3; nephrin-like 3; nephrin-like gene 1; NLG1; NLG1kin of irregular chiasm-like 2

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human/Mouse Kirrel2/NEPH3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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