Human/Mouse Osteocrin Antibody

Catalog #: MAB26201 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB26201
MAB26201-SP

All Osteocrin Antibodies

Product Details

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse Osteocrin Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects only the pro form (11 kDa) of human and mouse Osteocrin in direct ELISAs and Western blots.

Source

Monoclonal Rat IgG_2A Clone # 311413

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant mouse Osteocrin
Val28-Gly130
Accession # P61364

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Osteocrin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Osteocrin

Mouse Osteocrin, also known as Musclin, is a secreted protein that is primarily expressed in bone and muscle. It is synthesized as a proprotein (11 kDa) that undergoes proteolytic processing to generate a mature 50 amino acid 5 kDa C-terminal active peptide. It was found to modulate osteoblast differentation and to regulate glucose metabolism in muscles. Mouse Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and human protein, respectively.

Entrez Gene IDs

344901 (Human); 239790 (Mouse)

Alternate Names

Musclin; Osteocrin; OSTN