Human Nectin-4 PE-conjugated Antibody Summary
Gly27-Val351
Accession # Q96NY8
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Nectin-4 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Nectin-4 PE-conjugated Monoclonal Antibody (Catalog # FAB2659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Nectin-4
Nectin-4 is a type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is both a homophilic and heterophilic (with Nectin-1) cell adhesion molecule that is expressed in the embryo and in breast carcinoma. A soluble form of Nectin-4 is generated from the membrane protein via the action of TACE/ADAM-17. The extracellular domain of human Nectin-4 shares 90% and 92% amino acid sequence homology with the corresponding regions of mouse and rat Nectin-4, respectively.
Product Datasheets
Citations for Human Nectin-4 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
9
Citations: Showing 1 - 9
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Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
Authors: Miguel Ángel Muñoz-Alía, Rebecca A. Nace, Lianwen Zhang, Stephen J. Russell
Cell Reports Medicine
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A recombinant Chinese measles virus vaccine strain rMV-Hu191 inhibits human colorectal cancer growth through inducing autophagy and apoptosis regulating by PI3K/AKT pathway
Authors: CD Zhang, YL Wang, DM Zhou, MY Zhu, Y Lv, XQ Hao, CF Qu, Y Chen, WZ Gu, BQ Wu, PC Chen, ZY Zhao
Translational Oncology, 2021-04-10;14(7):101091.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: Flow Cytometry, Western Blot -
Mev-stealth: A cd46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum
Authors: MÁ Muñoz-Alía, RA Nace, A Tischer, L Zhang, ES Bah, M Auton, SJ Russell
PloS Pathogens, 2021-02-03;17(2):e1009283.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis
Authors: BM Laksono, P Fortugno, BM Nijmeijer, RD de Vries, S Cordisco, T Kuiken, TBH Geijtenbee, WP Duprex, F Brancati, RL de Swart
PLoS Pathog, 2020-10-08;16(10):e1008253.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells
Authors: T Hiramoto, M Tahara, J Liao, Y Soda, Y Miura, R Kurita, H Hamana, K Inoue, H Kohara, S Miyamoto, Y Hijikata, S Okano, Y Yamaguchi, Y Oda, K Ichiyanagi, H Toh, H Sasaki, H Kishi, A Ryo, A Muraguchi, M Takeda, K Tani
Mol. Ther., 2019-09-12;28(1):129-141.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins
Authors: MA Muñoz-Alía, SJ Russell
Viruses, 2019-07-27;11(8):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis
Authors: G Gourru-Les, C Mathieu, T Thevenet, V Guillaume-, JF Jégou, CG Boer, K Tomczak, LM Bloyet, C Giraud, S Grande, C Goujon, C Cornu, B Horvat
J. Dermatol. Sci, 2017-02-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
J. Immunol., 2011-12-16;188(3):1002-10.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Authors: Noyce RS, Bondre DG, Ha MN
PLoS Pathog., 2011-08-25;7(8):e1002240.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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Detection of human Nectin-4 on the SKBR3 breast cancer cell line. SKBR3 cells were treated with the human Nectin-4 PE-conjugated antibody (catalog # FAB2659P) (BLUE) or mouse IgG2b PE-conjugated isotype control antibody (RED)
