Human NFAM1 Antibody

Catalog #: MAB4046 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB4046
MAB4046-SP

All NFAM1 Antibodies

Product Details

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human NFAM1 Antibody Summary

Species Reactivity

Human

Specificity

Detects human NFAM1 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG_2B Clone # 374301

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant human NFAM1
Gln43-Lys163
Accession # Q8NET5

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human NFAM1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NFAM1

NFAM1 is a ~30 kDa transmembrane ITAM-containing glycoprotein of the Ig superfamily that activates the NFAT family of transcription factors. NFAM1 is expressed in leukocytes, predominantly splenic B and T cells, and is involved in B cell activation and signaling. The 121 aa human NFAM1 extracellular domain contains one V‑type Ig-like domain and shows 45% aa identity with mouse NFAM1. The 86 aa cytoplasmic domain contains one ITAM consensus sequence.

Long Name

NFAT Activating Protein with ITAM Motif 1

Entrez Gene IDs

150372 (Human); 74039 (Mouse); 362966 (Rat)

Alternate Names

calcinerin/NFAT-activating ITAM-containing protein; Calcineurin/NFAT-activating ITAM-containing protein; CNAIP; CNAIPbK126B4.4; FLJ40652; NFAM1; NFAT activating protein with ITAM motif 1; NFAT activation molecule 1; NFAT-activating protein with ITAM motif 1