Human NgR3/NgRH2 Biotinylated Antibody

Catalog #: BAF2920 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
BAF2920

All NgR3/NgRH2 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human NgR3/NgRH2 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human NgR3/NgRH2 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) NgRH1 is observed and less than 1% cross-reactivity with rhNgR is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human NgR3/NgRH2
Cys25-Ala419
Accession # Q86UN2

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human NgR3/NgRH2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NgR3/NgRH2

NgR3, also known as Nogo 66 receptor homolog 2 (NgRH2) and reticulon 4 receptor-like 1 (RTN4RL1), is a 60 kDa GPI-linked glycoprotein belonging to the family of leucine-rich repeat (LRR) proteins. It contains eight central LRRs that are flanked by a LRR N-terminal subdomain and a cysteine-rich C-terminal subdomain. Human NgR3 shares approximately 89% amino acid sequence homology with the mouse or rat protein.

Long Name

Nogo-66 Receptor-related Protein 3/Nogo-66 Receptor Homolog 2/Reticulon-4 Receptor-like 1

Entrez Gene IDs

146760 (Human); 237847 (Mouse)

Alternate Names

DKFZp547J144; NgR3; NgRH2; NGRL2; nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; reticulon 4 receptor-like 1; reticulon-4 receptor-like 1; RTN4RL1