Human NK1R PE-conjugated Antibody Summary
Accession # P25103
Customers also Viewed
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
View Larger
Detection of NK1R in HEK293 Human Cell Line Transfected with Human NK1R and eGFP by Flow Cytometry HEK293 human embryonic kidney cell line transfected with (A) human NK1R or (B) irrelevant protein, and eGFP was stained with Mouse Anti-Human NK1R PE-conjugated Monoclonal Antibody (Catalog # FAB66871P) or Mouse IgG3PE-conjugated Isotype Control (Catalog # IC007P, data not shown). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: NK1R
NK1R (Neurokinin-1 receptor), gene name TACR1 (tachykinin receptor-1), is an ~80 kDa 7-transmembrane glycoprotein receptor for the proinflammatory tachykinin neuropeptide, substance P. NK1R is constitutively or inducibly expressed on a wide variety of cells, including monocytes, macrophages, microglia, lymphocytes, neutrophils, mast cells, and neurons. The 407 amino acid (aa) human NK1R contains 89 extracellular aa over multiple segments which collectively share 92% aa identity with corresponding regions of mouse and rat NK1R. A ~50 kDa short isoform that ends at aa 311 lacks almost all of the C-terminal cytoplasmic signaling region. It is the only form expressed in human monocytes and undifferentiated THP-1 cells, and its function appears to differ from the long isoform.
Product Datasheets
FAQs
No product specific FAQs exist for this product, however you may
View all Antibody FAQsIsotype Controls
Staining Reagents
Reviews for Human NK1R PE-conjugated Antibody
There are currently no reviews for this product. Be the first to review Human NK1R PE-conjugated Antibody and earn rewards!
Have you used Human NK1R PE-conjugated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
