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Human NPRA/NPR1 (NP_000897) VersaClone cDNA

Catalog #: RDC2877 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
RDC2877
Human NPRA/NPR1 (NP_000897) VersaClone cDNA
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Human NPRA/NPR1 (NP_000897) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

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Product Datasheet
COA
SDS

Background: NPRA/NPR1

Natriuretic peptide receptor A/guanylate cyclase A (NPRA), also called NPR-1 or GC-A, is a 120 - 140 kDa type I transmembrane glycoprotein that is the primary receptor for natrietic peptides ANP and BNP. Binding of ANP to the extracellular ligand binding domain (aa 54 - 415), plus ATP to the intracellular kinase homology domain (aa 528 - 805) activates a cytoplasmic guanylate cyclase (aa 840 - 1023). NPRA is expressed most highly in kidney, adrenal and adipose tissue. Human NPRA extracellular domain shows 86%, 44% and 34% aa identity with mouse NPRA, human NPRB and human NPRC, respectively.

Long Name
Natriuretic Peptide Receptor A
Entrez Gene IDs
4881 (Human); 18160 (Mouse); 24603 (Rat)
Alternate Names
ANPa; ANP-A; ANPRA; ANPR-A; ANPRAEC 4.6.1.2; atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor type A; atrionatriuretic peptide receptor A; GC-A; Guanylate cyclase A; GUC2A; GUCY2A; natriuretic peptide A type receptor; natriuretic peptide receptor A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A); NPR1; NPRA; NPR-A; Pndr

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