Human NRL Biotinylated Antibody Summary
Met1-Leu237
Accession # P54845
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: NRL
NRL is a 30 kDa nuclear transcription factor that belongs to the Maf subfamily within the bZIP (basic motif-leucine zipper) transcription factor family. It contains an N‑terminal transcriptional activation domain and a C-terminal DNA-binding bZIP domain that is also involved in homo- or heterodimerization. NRL regulates the expression of rod-specific genes and is expressed specifically in rod photoreceptors. NRL is phosphorylated at multiple sites, which likely regulates its activity. The amino acid sequence of human NRL is 92%, 94%, 90% and 90% identical to that of bovine, canine, rat and mouse NRL, respectively.
Product Datasheets
Citations for Human NRL Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness
Sci Rep, 2016-07-29;6(0):30742.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13
Authors: Kent W. Small, Adam P. DeLuca, S. Scott Whitmore, Thomas Rosenberg, Rosemary Silva-Garcia, Nitin Udar et al.
Ophthalmology
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