Human Orai1 (NP_116179) VersaClone cDNA

Catalog #: RDC0434 Datasheet / COA / SDS

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RDC0434

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Human Orai1 (NP_116179) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Orai1

Orai1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Orai1 is a pore subunit of Ca(2+) release-activated Ca(2+) CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. This type of channel is the primary way for calcium influx into T-cells. Defects in Orai1 are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1.

Long Name

ORAI Calcium Release-activated Calcium Modulator 1

Entrez Gene IDs

84876 (Human); 109305 (Mouse)

Alternate Names

CRACM1; CRACM1ORAT1; FLJ14466; ORAI calcium release-activated calcium modulator 1; Orai1; ORAT1; Protein orai-1; TMEM142A; TMEM142Acalcium release-activated calcium modulator 1; Transmembrane protein 142Acalcium release-activated calcium channel protein 1

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