Home / Park7/DJ-1 / Human Park7/DJ-1 Biotinylated Antibody

Human Park7/DJ-1 Biotinylated Antibody

Catalog #: BAF3995
2 Citations Datasheet / COA / SDS
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BAF3995
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Citations (2)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Park7/DJ-1 Biotinylated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Park7/DJ-1 in Western blots. In this format, approximately 40% cross-reactivity with recombinant mouse Park7 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human Park7/DJ-1
Met1-Asp189
Accession # Q99497
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human Park7/DJ‑1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Park7/DJ-1

Park7, also known as DJ-1, is a cytoplasmic protein that belongs to the ThiJ/Pfp1/DJ-1 superfamily of highly conserved proteins that function as protein chaperones, catalases, proteases and kinases. Park7 is widely expressed in the brain as well as in peripheral tissues. It exists as a homodimer that can be localized in the cytoplasm, nucleus and mitochondria. Park7 is a redox-sensitive protein that has been ascribed various functions including that as a redox sensor and antioxidant protein. Mutations in Park7 are associated with a small percentage of hereditary early onset Parkinson’s disease.

Long Name
Parkinson Disease 7
Entrez Gene IDs
11315 (Human); 57320 (Mouse); 117287 (Rat)
Alternate Names
DJ1; DJ-1; DJ1FLJ34360; EC 3.4; FLJ27376; FLJ92274; Oncogene DJ1; Park7; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; protein DJ-1

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Citations for Human Park7/DJ-1 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Salivary DJ-1 could be an indicator of Parkinson's disease progression
    Authors: Wen-Yan Kang, Qiong Yang, Xu-Feng Jiang, Wei Chen, Lin-Yuan Zhang, Xiao-Ying Wang et al.
    Frontiers in Aging Neuroscience
  2. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease.
    Authors: Hong, Zhen, Shi, Min, Chung, Kathryn, Quinn, Joseph F, Peskind, Elaine R, Galasko, Douglas, Jankovic, Joseph, Zabetian, Cyrus P, Leverenz, James B, Baird, Geoffrey, Montine, Thomas J, Hancock, Aneeka M, Hwang, Hyejin, Pan, Catherin, Bradner, Joshua, Kang, Un J, Jensen, Poul H, Zhang, Jing
    Brain, 2010-02-15;133(0):713-26.
    Species: Human
    Sample Types: CSF
    Applications: Luminex Development

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