Human Podocalyxin Biotinylated Antibody Summary
Ser23-Arg427
Accession # AAB61574
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Podocalyxin
Podocalyxin, also known as Podocalyxin-like protein-1 (PCLP1 or PODXL), is a type I transmembrane glycoprotein. It belongs to the CD34/Podocalyxin family of sialomucins that share structural similarity and sequence homology. Podocalyxin is a major sialoprotein in the podocytes of the kidney glomerulus and is also expressed by both endothelium and multipotent hematopoietic progenitors. It has been identified as a novel cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells (1, 2).
Product Datasheets
Citations for Human Podocalyxin Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
8
Citations: Showing 1 - 8
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A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
Authors: Garreta E, Prado P, Stanifer ML et al.
Cell Metabolism
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Podocalyxin Expressed in Antigen Presenting Cells Promotes Interaction With T Cells and Alters Centrosome Translocation to the Contact Site
Authors: Laura Amo, Javier Díez-García, Estíbaliz Tamayo-Orbegozo, Natalia Maruri, Susana Larrucea
Frontiers in Immunology
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Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells
Authors: Garreta E, Prado P, Tarantino C et al.
Nature Materials
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Modeling of FAN1-Deficient Kidney Disease Using a Human Induced Pluripotent Stem Cell-Derived Kidney Organoid System
Authors: Lim, SW;Na, D;Lee, H;Fang, X;Cui, S;Shin, YJ;Lee, KI;Lee, JY;Yang, CW;Chung, BH;
Cells
Species: Human
Sample Types: Organoid, Whole Cells
Applications: IHC -
CRISPR-Cas9-Mediated Correction of SLC12A3 Gene Mutation Rescues the Gitelman's Disease Phenotype in a Patient-Derived Kidney Organoid System
Authors: SW Lim, X Fang, S Cui, H Lee, YJ Shin, EJ Ko, KI Lee, JY Lee, BH Chung, CW Yang
International Journal of Molecular Sciences, 2023-02-03;24(3):.
Species: Human
Sample Types: Organoid
Applications: IHC -
A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
Authors: Garreta E, Prado P, Stanifer ML et al.
Cell Metabolism
-
Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells
Authors: Garreta E, Prado P, Tarantino C et al.
Nature Materials
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Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system
Authors: S Cui, X Fang, H Lee, YJ Shin, ES Koh, S Chung, HS Park, SW Lim, KI Lee, JY Lee, CW Yang, BH Chung
Journal of Translational Medicine, 2023-02-22;21(1):138.
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