Home / Protogenin / Human Protogenin (NP_776175) VersaClone cDNA

Human Protogenin (NP_776175) VersaClone cDNA

Catalog #: RDC1953 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
RDC1953
R&D Systems VersaClone cDNA Plasmids
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Human Protogenin (NP_776175) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: Protogenin

Protogenin (Early/proto in expression, neogenin-like; also Prtg) is a 130 kDa (predicted), type I transmembrane member of the DCC/Neogenin family of proteins. It is expressed in mouse presomitic mesoderm, paraxial mesoderm, and neural tube. Mature mouse protogenin is 1168 amino acids (aa) in length. It contains a 920 aa extracellular domain (ECD) (aa 24 - 943) plus a 224 aa cytoplasmic region. The ECD contains four consecutive Ig-like domains (aa 24 - 405), followed by five sequential fibronectin type III domains (aa 413 - 908). The ECD of mouse protogenin shares 98%, 87% and 93% aa identity with the ECD of rat, chick and human protogenin, respectively.

Entrez Gene IDs
283659 (Human); 235472 (Mouse); 315806 (Rat)
Alternate Names
FLJ12795; FLJ13221; FLJ25756; IGDCC5; immunoglobulin superfamily, DCC subclass, member 5; Protein Shen-Dan; protogenin homolog (Gallus gallus); Protogenin; PRTG; RPTG; Shen-Dan

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