Human RAR gamma /NR1B3 Antibody

Catalog #: PP-H5620-00 Datasheet / COA / SDS

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PP-H5620-00

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human RAR gamma /NR1B3 Antibody Summary

Species Reactivity

Human

Specificity

This antibody specifically recognizes human RAR gamma and does not cross-react with human RAR alpha or RAR beta. Not yet tested in other species.

Source

Monoclonal Mouse IgG_2A Clone # H5620

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Recombinant human RAR gamma/NR1B3

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

This antibody can be used at 1 μg/mL under reducingconditions with the appropriate secondary reagents to detect human RAR gamma.

Immunoprecipitation

Optimal dilutions should be determined by eachlaboratory.

Direct ELISA

This antibody can be used at 60 ng/mL with the appropriatesecondary reagents to detect human RAR gamma.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RAR gamma/NR1B3

Retinoic Acid Receptor gamma (RAR gamma ; NR1B3) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR gamma is expressed in both adult and fetal skin. Along with other members of the RAR family, RAR gamma is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.

Long Name

Retinoic Acid Receptor, gamma

Entrez Gene IDs

5916 (Human)

Alternate Names

NR1B3; NR1B3RARC; Nuclear receptor subfamily 1 group B member 3; RAR gamma; RARC; RARG; RAR-gamma; retinoic acid receptor gamma; retinoic acid receptor, gamma