Human ROR alpha /NR1F1 Antibody Summary
Specificity
This antibody specifically recognizes human ROR alpha and does not cross-react
with human ROR beta or human ROR gamma. Not yet tested in other species.
Source
Monoclonal Mouse IgG2A Clone # H3910
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Recombinant human ROR alpha/NR1F1
aa 136-236
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Applications
Recommended Concentration
Sample
Western Blot
This antibody can be used at 1 μg/mL with the appropriatesecondary reagents to detect human ROR alpha.
Immunoprecipitation
Optimal dilutions should be determined by eachlaboratory.
Direct ELISA
This antibody can be used at 0.3 μg/mL with the appropriatesecondary reagents to detect human ROR alpha.
Please Note: Optimal dilutions should be determined by each laboratory for each application.
General Protocols
are available in the Technical Information section on our website.
Reconstitution Calculator
Reconstitution Calculator
Preparation and Storage
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
This antibody is stable for greater than six months when held at -20 °C in a
manual defrost freezer or at -70 °C. Upon thawing, the antibody can be
stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid
repeated freeze-thaw cycles.
Background: ROR alpha/NR1F1
Retinoic acid-related Orphan Receptor alpha (ROR alpha, RZR alpha, RORA; NR1F1)
is a member of the Orphan Nuclear Receptor family. ROR alpha is expressed in
the lung, muscle, brain, heart, peripheral blood leukocytes, spleen, liver, and
ovary. ROR alpha appears to have a general role in cell survival in the central
nervous system. Four isoforms are generated from the ROR alpha gene,
ROR alpha 1 - ROR alpha 4.
Long Name
Retinoic Acid-Related Orphan Receptor alpha
Entrez Gene IDs
6095 (Human)
Alternate Names
DKFZp686M2414; MGC119326; NR1F1; NR1F1MGC119329; nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; Retinoid-related orphan receptor-alpha; ROR alpha; ROR1; ROR2; ROR3; RORA; RZRA; RZR-ALPHA; RZRAROR-alpha; transcription factor RZR-alpha
Product Datasheets
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