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Human RTTN Antibody

Catalog #: MAB99661 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB99661-100
MAB99661-SP

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Human RTTN Antibody Summary

Species Reactivity
Human
Specificity
Detects human RTTN in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # 980404
Purification
Protein A or G purified from cell culture supernatant
Immunogen
Synthetic peptide containing human RTTN
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
ELISA

This antibody functions as an ELISA capture antibody when paired with Rabbit Anti-Human RTTN Monoclonal Antibody (Catalog # MAB9966).

This product is intended for assay development on various assay platforms requiring antibody pairs.

 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: RTTN

Human Rotatin, or RTTN, is a 2,226 amino acids (aa) protein discovered in a large-scale gene trap screen for factors that govern left-right specification. RTTN plays a role in the maintenance of a normal ciliary structure and is required for correct asymmetric expression of NODAL, LEFTY and PITX2.  In humans, RTTN mutations link aberrant ciliary function to abnormal development and organization of the cortex and might be a cause of Primary Microcephaly, Primordial Dwarfism and other brain malformations.

Long Name
Rotatin
Entrez Gene IDs
25914 (Human); 246102 (Mouse); 291377 (Rat)
Alternate Names
DKFZp434G145; FLJ26356; FLJ39085; MSSP; PMGYS; Rotatin; RTTN

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