Human S1P1/EDG-1 PE-conjugated Antibody
Human S1P1/EDG-1 PE-conjugated Antibody Summary
Met1-Ser382
Accession # P21453
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data

Detection of S1P1/EDG‑1 in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG-1 PE-conjugated Monoclonal Antibody (Catalog # FAB2016P). Quadrant markers were set based on control antibody staining (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: S1P1/EDG-1
S1P1, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.
Product Datasheets
Citations for Human S1P1/EDG-1 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 5
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A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models
Authors: J Jin, N Xue, Y Liu, R Fu, M Wang, M Ji, F Lai, J Hu, X Wang, Q Xiao, X Zhang, D Yin, L Bai, X Chen, S Rao
Acta Pharm Sin B, 2019-11-14;10(2):276-288.
Species: Hamster
Sample Types: Whole Cells
Applications: Flow Cytometry -
Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients
Authors: P Annunziata, C Cioni, G Masi, M Tassi, G Marotta, S Severi
Sci Rep, 2018-10-18;8(1):15371.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406.
Authors: Borge M, Remes Lenicov F, Nannini P, de los Rios Alicandu M, Podaza E, Ceballos A, Fernandez Grecco H, Cabrejo M, Bezares R, Morande P, Oppezzo P, Giordano M, Gamberale R
J Immunol, 2014-08-15;193(6):3165-74.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Authors: Llinas L, Lazaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P
Immunol. Lett., 2010-10-15;134(2):113-21.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases
Authors: King Faisal Yambire, Lorena Fernandez-Mosquera, Robert Steinfeld, Christiane Mühle, Elina Ikonen, Ira Milosevic et al.
eLife
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