Human SLITRK4 Antibody

Catalog # Availability Size / Price Qty
MAB2860
MAB2860-SP
Product Details
Citations (1)
FAQs
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Human SLITRK4 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SLITRK4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human SLITRK1, 2, 3, or 5 is observed.
Source
Monoclonal Mouse IgG2A Clone # 319514
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human SLITRK4
Asp19-Pro616
Accession # Q8IW52
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human SLITRK4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SLITRK4

Slit and Trk like gene 4 (SLITRK4) is one of six type I transmembrane (TM) proteins that belong to the SLITRK family of neurite guidance molecules. The extracellular region contains two blocks of leucine-rich repeats that are bounded by small cysteine-rich domains. The cytoplasmic region contains potential tyrosine kinase motifs reminiscent of the motifs on Trk receptors. Human SLITRK4 extracellular domain shares 98% aa sequence identity with the extracellular domains of both canine and mouse SLITRK4.

Long Name
SLIT and NTRK-like Family, Member 4
Entrez Gene IDs
139065 (Human); 245446 (Mouse)
Alternate Names
DKFZp547M2010; SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4; slit and trk like gene 4; SLITRK4

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Citation for Human SLITRK4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins
    Authors: PS Caceres, D Gravotta, PJ Zager, N Dephoure, E Rodriguez-
    Proc. Natl. Acad. Sci. U.S.A., 2019-05-29;116(24):11796-11805.
    Species: Canine
    Sample Types: Cell Lysates
    Applications: Western Blot

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