Human Somatostatin R3/SSTR3 Antibody

Catalog #: MAB7018 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB7018
MAB7018-SP

Detection of SSTR3 in PC‑3 Human Cell Line by Flow Cytometry.

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Human Somatostatin R3/SSTR3 Antibody Summary

Species Reactivity

Human

Specificity

Detects human Somatostatin R3/SSTR3

Source

Monoclonal Mouse IgG_2A Clone # 576017

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

NS0 mouse myeloma cell line transfected with human Somatostatin R3/SSTR3
Accession # P32745

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Flow Cytometry

2.5 µg/10⁶ cells

See below

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of SSTR3 in PC‑3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Somatostatin R3/ SSTR3 Monoclonal Antibody (Catalog # MAB7018, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

Reconstitution Calculator

Preparation and Storage

Reconstitution

Sterile PBS to a final concentration of 0.5 mg/mL.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Somatostatin R3/SSTR3

Somatostatin Receptor 3 (SSTR3) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR3 shares 80% aa identity with mouse SSTR3 within the extracellular domains. SSTR3 protein has been detected in anterior pituitary, lymphocytes, thyroid, parathyroid, stomach, small intestine, and pancreatic islets. In neurons, it is located within cilia and is implicated in object recognition memory. It is an inhibitory receptor that transduces the antiproliferative and antisecretive effects of somatostatins in the pituitary.

Long Name

Somatostatin Receptor Type 3

Entrez Gene IDs

6753 (Human); 20607 (Mouse); 171044 (Rat)

Alternate Names

Somatostatin R3; somatostatin receptor 3; SomatostatinR3; SS-3-R; SS3-R; SSR-28; SST3; SSTR3

Product Datasheets

Product Datasheet

COA

SDS

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