Human TMEFF1/Tomoregulin-1 Antibody

Catalog #: AF1919 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF1919
AF1919-SP

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TMEFF1/Tomoregulin-1 Antibody Summary

Species Reactivity

Human

Specificity

Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse TMEFF1 is observed and less than 1% cross‑reactivity with recombinant human TMEFF2 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1
Ser40-Thr328
Accession # Q8IYR6

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human TMEFF1/Tomoregulin‑1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TMEFF1/Tomoregulin-1

TMEFF1, also known as tomoregulin 1 is a type I transmembrane glycoprotein that contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain can be released as a soluble protein. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Entrez Gene IDs

8577 (Human); 230157 (Mouse)

Alternate Names

C9orf2; H7365member 1; TMEFF1; Tomoregulin1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1