Home / TR alpha/NR1A1 / Human TR alpha /NR1A1 Antibody

Human TR alpha /NR1A1 Antibody

Catalog #: PP-H2804-00
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
PP-H2804-00
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TR alpha /NR1A1 Antibody Summary

Species Reactivity
Human
Specificity
This antibody specifically recognizes human TR alpha and cross-reacts with mouse and rat TR alpha. The antibody does not cross-react with human TR beta. Not yet tested in other species.
Source
Monoclonal Mouse IgG2A Clone # H2804
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Recombinant human TR alpha/NR1A1
aa 2-51
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
This antibody can be used at 1 μg/mL under reducingconditions and at 3 μg/mL under non-reducing conditions with the appropriatesecondary reagents to detect human TR alpha.
 
Immunohistochemistry
This antibody can be used at 20 - 50 μg/mL withthe appropriate secondary reagents to detect human TR alpha.
 
Direct ELISA
This antibody can be used at 0.1 μg/mL with the appropriatesecondary reagents to detect human TR alpha.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: TR alpha/NR1A1

Thyroid Hormone Receptor alpha (TR alpha, THRA; NR1A1) is a member of the Nuclear Hormone Receptor superfamily. The ligands for TR alpha are the thyroid hormones, which exist in two forms: T4 and T3. TR alpha plays a critical role in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the Retinoid X Receptors (RXRs), which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of TR.

Long Name
Thyroid Hormone Receptor alpha
Entrez Gene IDs
7067 (Human)
Alternate Names
AR7; c-ERBA-1; c-erbA-alpha; EAR7; EAR-7; EAR-7.1/EAR-7.2; ERBA; ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog); ERBA-related 7; MGC000261; MGC43240; NR1A 1; NR1A1; NR1A1THRA3; Nuclear receptor subfamily 1 group A member 1; THRA; THRA1ERB-T-1; THRA2; thyroid hormone receptor alpha; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian); TR alpha; triiodothyronine receptor; v-ErbA1; V-erbA-related protein 7

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citation for Human TR alpha /NR1A1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Thyroid Hormone Receptor beta Knockdown Reduces Suppression of Progestins by Activating the mTOR Pathway in Endometrial Cancer Cells
    Authors: B Ren, J Zhou, Y Hu, R Zhong, Q Lv, S Xie, G Li, B Yang, X Chen, Y Zhu
    International Journal of Molecular Sciences, 2022-10-19;23(20):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human TR alpha /NR1A1 Antibody

There are currently no reviews for this product. Be the first to review Human TR alpha /NR1A1 Antibody and earn rewards!

Have you used Human TR alpha /NR1A1 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review